Browsing by Author "Jain, R."
Now showing 1 - 3 of 3
Results Per Page
Sort Options
Item Assessing Success Of Vaginal Birth After Cesarean By FLAMM Model In A Retrospective Observational Design(Association of Health Professionals and Health Educators, 2021-07) Mahadik, K; Tyagi, A; Yadav, A; Sultana, R; Jain, R.Background: After year 2000 cesareanrates have increased from 15% to 30-50% worldwide. Practice of Trial of labor after cesarean has decreased from last two decades of 20thcentury. Predictors of vaginal birth after cesarean are not uniform and not suitable equally for all populations. FLAMM model was tested in this study for its predictability for a successful vaginal birth after previous one cesarean. Material And Methods:For an observational, retrospective study 72 patient files admitted in 2018 in Obstetric Department of C R Gardi Hospital were included which fulfille d criteria of having second pregnancy after cesarean for non recurrent indications like fataldistress, failure of induction of labor, pre-eclampsia, eclampsia, twins and others. Indication of contracted pelvis, rupture uterus, previous classical cesarean section; and multiple pregnancy, medical complications and obstetric complications in this pregnancywere excluded. FLAMM scoreparameters; cervical dilatation, effacement, presence of previous vaginal birth before cesarean, indication of it and age of woman wereused. Observations of successful and failed trial were done by scoring system. Chi square test was used to compare data. Study variables were success of trial in various FLAMM parameters. Result:Higher scores in cervical dilatation (p<0.001), effacement (p<0.001) and prior vaginal delivery (p=0.03) were significantly associated with a successful outcome. Higher theaggregate FLAMM score, higher were chances of successful trial. A non-recurrent indication other than non-progress of labor for previous cesarean had no statistical association with success of trial. Aggregate score of 6 and more has 100 % predictability for a successful vaginal birth. Conclusion:Prediction by FLAMM model resulted in 62. 5%successful trial. FLAMM model maybe used for near to accurate prediction of successful trial of labor after cesarean.Item Morphological and anatomical aberrations induced by waterlogging in sugarcane(Triveni Enterprises, 2019-07) Jain, R.; Singh, A.; Singh, S.P.; Chandra, A.; Pathak, A.D.Aim: The present investigation was carried out to study root anatomy of sugarcane cultivars (CoLk 94184 and CoJ64) planted under waterlogged condition through Scanning Electron Microscopy (SEM). Methodology: Two sugarcane (Saccharum spp. hybrid) cultivars, CoLk 94184 and CoJ 64 were evaluated for changes in root anatomy in response to waterlogging during 2017-2018. For waterlogging treatment, crop was grown in deep plot which was waterlogged upto a depth of 1 m during active grand growth stage (monsoon season) along with untreated control plot. After three months of waterlogging, the plants were uprooted to study the root morphology and anatomy through SEM. Results: Waterlogged plants showed aerial root formation in both the cultivars but number and mass were higher in CoJ64. Aerenchyma was formed in the cortical region of both control and waterlogging roots but the size was relatively increased in waterlogged. Irregular and damaged surface cells with longer root hairs were observed in waterlogging treatment. Waterlogged roots exhibited cell distortion, loss of uniformity in endodermis and pericycle regions and higher number of metaxylem vessels. Interpretation: The study concluded that waterlogging treatment caused structural anomalies and induced anatomical and surface ultra-structural changes in both the cultivars, but the level of deformation was relatively higher in genotype CoJ 64, indicating sensitivity towards waterlogging as compared to cultivar CoLk 94184.Item Novel Hptlc-Densitometric Method For The Estimation Of Teriflunomide In Tablet Dosage Form(Innovare Academic Sciences Pvt. Ltd., 2019-06) Vishwas, T. S.; Gurupadayya, B. M.; Jain, R.Objective: The current work is intended towards the development of a novel, simple and precise high-performance thin layer chromatographic (HPTLC) method coupled with a densitometer for the estimation of teriflunomide (TEF) present in the marketed formulation. Methods: The chromatographic development was performed on aluminum plates coated with silica gel 60 F254 using toluene: ethyl acetate: glacial acetic acid (7.5:2: 0.5 v/v/v) as the mobile phase. Densitometric scanning was achieved at the absorbance maxima, UV 284 nm. Results: Well separated band was observed with Rf value 0.46. The calibration curve plotted in the concentration range 100-700ng/band exhibited an excellent linear relationship with the r2 value of 0.9928. The method was found to comply with all the validation parameters as per the ICH guidelines. Conclusion: The method ensures minimal use of mobile phase with minimal run time compared to other reported analytical methods. This validated method can be used by quality control laboratories for the routine quantitative analysis of tablets consisting of Teriflunomide.