Browsing by Author "Jain, Akash"
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Item High-grade myxofibrosarcoma-presented as a large mass of right upper arm.(2015-01) Jagtap, Sunil Vitthalrao; Jain, Akash; Jagtap, Swati S; Kshirsagar, Ashok YMyxofi brosarcoma is one of the rare soft tissue sarcomas. We present a case of a 65-year-old male having large soft tissue mass over right upper arm associated with surface ulceration. On histopathological study tumor was diagnosed as myxofi brosarcoma – high grade according to modifi ed FNCLCC grading system. Like many other tumors of connective tissue, soft tissue sarcoma exhibits high recurrence. In our case, tumor showed features of high grade with local recurrence, large size; however, no evidence of metastasis was noted. For this unpredictable clinical behavior, we are presenting this case.Item Novel 4-hydroxy-N'-[(1E)-substituted-phenylmethylidene] benzohydrazide analogs (hydrazones) as potent antibacterial and anti-oxidant agents(Open Science Publishers LLP, 2019-12) Chaudhary, Jasmine; Jain, Akash; Manuja, RohiniIn the present study, a series of 4-hydroxy-Nʹ-[(1E)-substituted-phenylmethylidene] benzohydrazide analogs was synthesized, characterized, and evaluated for their antibacterial and anti-oxidant activity. All the tested compounds show high antibacterial activity with compound AR7 , Nʹ-(3,4,5-trimethoxybenzylidene)-4-hydroxybenzohydrazide as the most active compound, whereas compounds AR10 (hydrogen peroxide scavenging) and AR8 (2,2-diphenyl-1- picrylhydrazyl radical scavenging activity method) were found to possess maximum anti-oxidant activity indicating that different mechanisms are involved in different anti-oxidant determination methods.