Browsing by Author "Hussain, S"

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    Al-Adwiyah Al-Qalbiyah: introduction and commentary.
    (1994-07-01) Azmi, K A; Hussain, S
    Avicenna was a great scientist and philosopher of the 10th century A.D. He wrote about 456 books in various fields of learning. Al-Adwiyah Al-Qalbiyah is perhaps the most important work of Avicenna after Al-Qanun fil Tibb or canon of medicine. Like Al-Qanun, it was also very popular in Europe and was translated into Latin. It has also been translated in Turkish, Uzbbek, and later on in Persian and Urdu.
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    Assessment of drug prescribing pattern using world health organization indicators in a tertiary care teaching hospital
    (Indian Public Health Association, 2018-06) Hussain, S; Yadav, SS; Sawlani, KK; Khattri, S
    This cross-sectional study was carried out to assess drug prescribing pattern at a tertiary care teaching medical institute. One thousand prescriptions were randomly collected and analyzed using the world health organization prescribing indicators. The average number of drugs per prescription was 2.91. The percentage of drugs prescribed by generic name, from the essential drug list (National) and as fixed dose combinations (FDCs) was 10.05%, 22.57%, and 49.22%, respectively. The total percentage of encounters with antibiotics, injectables, and FDCs was 19.70%, 2.20%, and 73.60%, respectively. The most common group of drug prescribed was gastrointestinal tract drugs (26.38%) followed by Vitamins and Minerals (23.12%), cardiovascular system drugs (11.56%) and antimicrobials (9.63%). The prescribing practices were not appropriate as they consist of polypharmacy, lesser prescription by generic name, and overprescription of FDCs. There is a need for improvement in the standards of prescribing patterns in many aspects.
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    Body fluids according to Avicenna.
    (1983-07-01) Hussain, S
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    Comparison of fasting versus postprandial thyroid function test and growth hormone status in known subclinical hypothyroid patients based on hormonal changes in medical college and hospital, Kolkata
    (?Eldaghayes Publisher, 2024-10) Karar, N; Datta, S; Datta, S; Biswas, S; Hussain, S; Sen, P; Samaddar, R; Samaddar, A.
    Background: Thyroxine (T4) and triiodothyronine are the main thyroid hormones that play an essential role in cellular metabolism, growth, and tissue development, and subclinical hypothyroidism (SCH) is often defined by a thyroid-stimulating hormone (TSH) level above the upper limit of the reference range (usually around 4.0 or 4.5 mIU/L, usually TSH level in between 4 and 10 mIU/mL) along with a normal free T4 (fT4) level. Previous studies undertaken in various parts of the world have shown food intake can influence the TSH level at different percentages and these studies speculated that if we measure TSH level 2 h after breakfast (9:00 am) compared with the fasting blood samples that is generally collected in the morning (7:00 am), the TSH level is significantly reduced by about 30%, and this significant difference created reasonable doubt in the diagnosis of SCH. Aims and Objectives: The study aimed to evaluate the difference in serum TSH, fT4, leptin, cortisol, insulin, adiponectin, and glucagon-like peptide-1 (GLP-1) between fasting and post-prandial blood samples in known subclinical hypothyroid patients. Materials and Methods: This descriptive, cross-sectional, non-interventional study was done on 50 diagnosed subclinical hypothyroid patients after screening them through the inclusion–exclusion criteria. The estimations were done by chemiluminescence immunoassay or enzyme-linked immunosorbent assay method, statistical analysis was done using Statistical Packages for the Social Sciences. Results: After analysis of blood samples, it showed that the serum TSH decreased progressively after food intake for almost 2 h, the level of decrease is statistically significant (from 7.38 ± 1.22 mIU/mL to 5.9 ± 1.03 mIU/mL) (P < 0.001). Serum fT4 level remained almost unchanged after food intake. Conclusion: As per previous and our study a possible explanation of this post-prandial fall of TSH can be that food consumption causes an alteration in circulating glucose levels, insulin, leptin, gastric inhibitory polypeptide (cholecystokinin and GLP-1), and cortisol. Growth hormone (GH) and somatostatin levels also suppress TSH secretion from the pituitary. As both over- and under-treatment with eltroxin can be detrimental for subclinical hypothyroid children and pregnant women, so further studies with larger sample sizes and somatostatin and GH estimation should be done to authenticate the findings of this study.
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    A Comprehensive Guide to Interpreting Quality of Life in Elderly patients with Controlled and Uncontrolled Diabetes
    (?Eldaghayes Publisher, 2024-12) Hussain, MS; Hussain, S; Jakhar, A; Usman, K; Sawlani, KK; Khattri, S.
    Background: Because old adults with type 2 diabetes are associated with an increase in mortality and complications when compared to young diabetics and non-diabetic people of the same age group, the elderly are at a high risk for this condition. Diabetes affected nearly 19 million people in 2010, accounting for 26.9% of all those in this age range. The most important factor in determining a person’s level of health is their quality of life (QOL). Aim and objectives: The aims of this study are to determine the QOL in controlled and uncontrolled geriatric type 2 diabetes mellitus patients receiving antidiabetic drug therapy using the World Health Organization Quality of Life— BREF (WHOQOL-BREF) and Appraisal of Diabetes Scale (ADS) questionnaire. Materials and methods: This prospective, cross-sectional, observational study began following ethical approval. The study covered 182 patients. Categorical data were compared using the chi-square test, whilst normally distributed con- tinuous data were examined using the unpaired t-test. The odd ratios for quality-of-life impairment were determined using univariate binary logistic regression analysis (QOL). Results: Across the groups of people with controlled and uncontrolled diabetes, there were significant differences in family structure and marital status (p<0.05). When compared to the group with controlled diabetes (133.55 ± 49.01 and 6.16 ± 0.33) the FPG and HbA1c were considerably higher in the uncontrolled diabetes group (154.73 ± 55.18 and 7.81 ± 1.11). In the two groups, there was a substantially different duration of diabetes mellitus (p = 0.004). Conclusions: There were significant variations in the mean age, HbA1c (%), FPG, and duration of diabetes mellitus and widowed patients between the uncontrolled and controlled diabetes groups, resulting in a reduced quality of life in uncontrolled diabetes patients.
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    Cortical blindness: an unusual presentation of eclampsia.
    (2001-12-09) Hassan, A; Hussain, S; Khalid, A
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    Dicrotic notch in females.
    (1998-07-19) Hussain, S; Subhash, E
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    Dicrotic wave and anthropometry.
    (1997-04-01) Hussain, S; Ahmed, M Y
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    The direct cost of treating bronchial asthma in a teaching hospital in Malaysia.
    (2002-09-16) Chan, P W K; Hussain, S; Ghani, N H; Debruyne, J A; Liam, C K
    A pilot study to evaluate the direct cost of treating 51 adults and 50 children with bronchial asthma was conducted. All aspects of the medical care provided over a 6-month period were considered. The mean treatment costs per month were US dollars 22.97 (adults) and US dollars 15.56 (children). The cost of maintenance therapy accounted for 55.5% and 73.4% of the total direct cost treatment for adults and children respectively. Only 27 (52.9%) adults and 17 (34.0%) children paid for their inhaled prophylactic drugs, amounting to 12.3% of the total maintenance therapy costs. Thirteen (25.4%) adults and 9 (18.0%) children were using alternative therapy at a monthly cost of US dollars 41.50 and US dollars 16.77 respectively. A substantial proportion of the direct cost of asthma treatment is heavily subsidized in Malaysia. Adequate attention to the allocation of the health budget, to ensure the optimal provision of health care, is warranted.
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    Eradication of Helicobacter pylori with a metronidazole-containing regimen in a metronidazole-abusing population.
    (2001-01-24) Janan, F A; Ahmad, M M; Rowshon, A H; Hussain, S; Hussain, M; Rahim, S; Rahman, M M; Rahman, A T; Karim, M Z
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    Hyperteleorism.
    (1968-02-01) Gambhir, M S; Parikh, K L; Hussain, S
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    Local Autologous Blood Injection Versus Corticosteroid Injection in the Treatment of Lateral Epicondylitis- A Prospective Comparative Study
    (Society for Scientific Research, 2024-07) Baruah, RK; Pegu, H; Chamlagai, MK; Hussain, S
    Background: Lateral epicondylitis, also known as tennis elbow, is characterized by pain and tenderness at the lateral epicondyle of the humerus that worsens with grip and dorsiflexion of the wrist against resistance. Methods: This prospective study was carried out at our institution from July 2013 to June 2014, with approval from the ethical committee. Sixty patients with clinically diagnosed lateral epicondylitis were divided into two groups: Group A received local autologous blood, and Group B received local corticosteroid injections. Patients were evaluated using the Thomsen provocative test with Visual Analogue Scale, patient-rated tennis elbow evaluation score, and maximal grip strength at baseline (before injection) and 4 weeks, 12 weeks, and 24 weeks after injection. The statistical analysis used paired and unpaired t-tests, with significance set at p<0.05. Results: Both treatment groups showed significant improvements in pain and function at 24 weeks compared to baseline. However, Group B (corticosteroid injection) demonstrated superior short-term outcomes at 4 weeks in pain reduction and grip strength. In contrast, Group A (autologous blood injection) exhibited better long-term outcomes at 24 weeks with statistically significant improvements in pain reduction (71.3% vs. 45.5%), patient-rated tennis elbow evaluation scores (50.67% vs. 37.72%), and grip strength (24.19% vs. 13.69%) compared to Group B. Conclusion: Autologous blood injection therapy appears to be a promising treatment option for lateral epicondylitis, offering superior long-term outcomes compared to corticosteroid injection. While corticosteroid injection showed initial advantages in short-term pain relief and grip strength, autologous blood injection resulted in sustained improvements over the 24-week followup period. These findings support autologous blood injection as a preferred treatment option due to its effectiveness and lower recurrence rates, suggesting its consideration in clinical practice for managing lateral epicondylitis.
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    Osteopetrosis-(Albers-Schonberg's disease).
    (1968-09-01) Bhandari, N R; Inamdar, S; Jungalwala, B N; Hussain, S
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    PEFR in cement pipe factory workers.
    (1999-07-25) Hussain, S; Mohiuddin, M; Shakeel-Ur-Rehman, M; Rafiq, A; Ahmed, M A
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    PEFR in relation to phases of pregnancy.
    (2000-10-24) Rasheed, B M; Hussain, K; Hussain, S
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    Pharmacoeconomic Evaluation of Antidiabetic Medication in Geriatric Type 2 Diabetes- A Brief Study
    (?Eldaghayes Publisher, 2024-12) Jakhar, A; Hussain, S; Hussain, MS; Saifi, L; Usman, K; Sawlani, KK; Khattri, S.
    Introduction: Diabetes mellitus (DM) is a long-term condition that poses an enormous health and economic burden on society. Unfortunately, there is a dearth of such evidence in India. Hence, we sought to estimate the direct cost of antidiabetic medication in the geriatric population. Aim and Objectives: The aim of this study is to evaluate the pharmacoeconomic of antidiabetic medication in geriat- ric type 2 diabetes mellitus patients attending outpatient department in a tertiary care teaching hospital. Materials and Methods: The demographic characteristics, clinical characteristics, and treatment profiles of patients were compiled. All diabetic patients who visited an outpatient department had their prescriptions recorded. A pharma- coeconomic analysis of prescribed anti-diabetic medications was conducted. Results: The study enrolled 600 DM patients, of which 67.83% were males, 32.17 % were females, and the pre- dominant age group was 60–64 years. In 94.54% of patients, the most frequently prescribed antidiabetic drug was metformin 500 mg. In 39.31% of patients, the most frequently prescribed antidiabetic combination was glimepiride 2 mg + metformin 500 mg. Insulin was prescribed in 14.83% of the cases. The percentage cost difference for diabetes medications ranges from 43.010 to 644.444. The monthly cost of monotherapy for most patients with controlled diabe- tes (31.46%) and uncontrolled diabetes (42.12%) was between 500 and 1000 INR. In addition, the cost of combination therapy ranges between INR 118.91 and INR 300.27. Conclusion: The costs associated with diabetes are immense and impose a substantial burden on society. Consequent- ly, policymakers should prioritize preventing the disease and its associated problems.
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    Poisoning by Oral Ingestion of Wild Berries.
    (2007-04) Kamili, M A; Dar, Ishrat Hussain; Ali, G; Wazir, H S; Hussain, S
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    Prevalence of coronary heart disease in Kashmiris.
    (2007-01-23) Kamili, Ma; Dar, Ih; Ali, G; Wazir, Hs; Hussain, S
    Coronary Heart Disease (CHD) is one of the major causes of mortality and morbidity in the general population of both the developing and developed countries. Prevalence of CHD in the Indian subcontinent is presently one of the highest and is further on an increase. In the state of Jammu and Kashmir the population like any other developing community, is undergoing lifestyle changes but the unusual stress and strain for the last 15 years of the disturbed situation in the state apparently has contributed to increase the prevalence of CHD. Therefore an epidemiological study was conducted to assess the prevalence of CHD in both rural and urban areas of the valley. This study was carried out in the rural and urban areas of the twin districts of Anantnag and Srinagar by random sampling. The total population of the study area comprised of 44,305 persons out of which the target population was 13,893. The study was carried out on 3128 (23%) subjects (2284 males and 844 females) aged 40 years and above. In rural areas the study was conducted in a cluster of 3 villages in each district on 1552 persons (1088 males and 464 females) and in urban areas it was carried out in 3 mohallas (closed locality) in each district on 1576 persons (1196 males and 380 females). A complete history and clinical examination was done and Rose Questionnaire was recorded for angina. ECG was done in all subjects. Chi square test was used for statistical analysis. The overall prevalence of CHD in the population studied by all diagnostic measures was 7.54%. The overall rural prevalence was 6.70% and urban prevalence was 8.37%. Prevalence of CHD was higher in males, 7.88% and slightly lower in females, 6.63%.
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    Quranic description of gametes.
    (1999-07-18) Hussain, S
    There are several important characteristic properties of reproductive fluid. Gametes are the reproductive cells consisting of sperms in males and ovum in females. These cells combine to form Zygote in the process of fertilization. The characters of Gametes have been narrated by Holy Quran in a very well-suited and selected terminology. This paper enumerates various Quranic terms related to gametes, and then discusses their scientific significance.