Browsing by Author "Haque, SMZ"

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    The Association between Platelet Lymphocyte Ratio and In-Hospital Outcomes in Patients with First Attack of Acute ST-elevation Myocardial Infraction following Thrombolysis with Streptokinase in a Tertiary Care Hospital
    (Ms. M. B. Mondal, 2024-07) Kamal, A-M; Kamal, M; Ahmed, S; Kamal, A; Alam, I; Khan, MH; Haque, SMZ; Amin, R; Ali, MNT
    Introduction: Platelet Lymphocyte ratio (PLR) has been found to be a good predictor of future adverse cardiovascular outcomes in patients with ST-segment elevation myocardial infarction (STEMI). Aim: Investigation was done in the aim to detect the role of Platelet Lymphocyte ratio (PLR) in predicting in-hospital adverse cardiac events in patients with STEMI thrombolysed with streptokinase in a tertiary care hospital. Methods: This cross sectional descriptive study carried out in the Department of Cardiology, Mymensingh Medical College Hospital, Mymensingh for fifteen-month duration from January, 2018 to March, 2019, in STEMI patients, who were thrombolysed with inj. Streptokinase (STK) had blood samples at admission, analyzed complete blood counts for PLR calculation. They were grouped into two, low and high PLR, taking 150 as cut-off. Chi square test was used to compare rate of adverse events and death in hospital stay. Logistic regression analysis was used to estimate predictive ability of PLR for in-hospital cardiac events. Results: A total of 79 patients among 217 patients had complications. Patients in high PLR group had higher rate of complications (63.6% vs. 21.4%, p <0.001) in hospital than those in low PLR group. Arrhythmias (13.0% vs. 5.0%, p <0.036), Heart failure (45.5% vs. 15.0%, p=0.001), Cardiogenic shock (10.4% vs.3.6%, p <0.001), Death (9.1% vs. 6.4%, p=0.473), occurred more in high PLR group. Mean PLR was significantly different between Group-I and Group-II (96.21±27.79 vs. 233.21±88.20, p<0.001). Multivariate regression analysis showed PLR an independent predictor of in-hospital adverse cardiac events (at 10% level of significance, p = 0.001). Conclusion: High admission PLR is an independent predictor for in-hospital adverse cardiac events in patients hospitalized for STEMI thrombolysed with streptokinase.
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    Percutaneous Angioplasty and Stenting of Carotid Artery: Study of 18 Cases.
    (2010) Momenuzzaman, N A M; Begam, F; Khan, K N; Dey, A; Adhikary, D K; Ilius, Z M; Sohail, K M; Haque, F; Amin, M U; Mallick, S k; Haque, SMZ
    Background: Carotid angioplasty & stenting is becoming an emerging therapeutic option for carotid revascularization. The use of cerebral protection system has expanded the area of application of the procedure worldwide. Purpose: To assess the feasibility, success rate, safety as well as in-hospital & early 30 days outcome in patients undergoing percutaneous carotid intervention. Methods: A retrospective, observational study where a total of 18 (Eighteen) consecutive patients who presented with symptomatic and > 70 % carotid artery stenosis & asymptomatic but > 90% stenosis underwent percutaneous carotid intervention. All of them had coronary artery disease; CABG was done in 3 patients & PCI in 9 patients. Three of them had previous stroke (Ischemic) & 7 had TIA. Results: Technical and angiographic success was achieved in all patients. Carotid artery obstruction diminishes from 85 + 14 % to 10 + 5 % (p< .001). Mean lesion length was 12 + 3 mm and mean time of carotid occlusion during balloon inflation was 10 + 2.5 sec. distal protection devices used in all patents. No major stroke or death occurred during procedure. One patient developed No-flow because of obstruction of distal protection device which was managed by thrombosuction. One patient developed TIA. All patients were discharged from hospital after an average of 3 days & all of them were prescribed dual antiplatalet therapy for 6 months. During follow-up one patient died secondary to acute myocardial infarction and one patient developed major stroke. Conclusion: Percutaneous angioplasty and stenting associated with distal protective devices appear feasible, effective and almost safe endovascular treatment modality for carotid artery stenosis.