Browsing by Author "Gupta, R S"
Now showing 1 - 20 of 35
Results Per Page
Sort Options
Item Actions of prostaglandins E1, E2, F1, alpha and F2alpha in ouabain-induced arrhythmia and maximal electroshock seizures.(1974-11-01) Madan, B R; Gupta, R S; Madan, VItem Antibiotic sensitivity pattern of various Lactobacillus acidophilus strains.(1995-08-01) Gupta, P K; Mital, B K; Gupta, R SSeven L. acidophilus strains were examined for their antibiotic sensitivity against various chemotherapeutic agents and all of them were found to be sensitive to novobicin, chloramphenicol, ampicillin, erythromycin, oxytetracycline and chlorotetracycline, whereas, all were resistant to norfloxacin and nalidixic acid. The sensitivity towards remaining antibiotics varied among the strains. The results show that cultures should be tested for their sensitivity towards commonly used chemotherapeutic agents to eliminate starter failure during manufacture of cultured milk products.Item Antifertility effect of Tinospora cordifolia (Willd.) stem extract in male rats.(2003-08-14) Gupta, R S; Sharma, ArunaOral administration of 70% methanolic extract of T. cordifolia stem to male rats at the dose level of 100 mg/rat/day for 60 days did not cause body weight loss but decreased the weight of testes, epididymis, seminal vesicle and ventral prostate in a significant manner. Sperm motility as well as sperm density were reduced significantly which resulted in reduction of male fertility by 100%. The stem extract brought about an interference with spermatogenesis. The round spermatids were decreased by 73.12%. However, the population of preleptotene and pachytene spermatocytes were decreased by 47.60% and 52.85% respectively, followed by secondary spermatocytes (48.10%). Leydig cell nuclear area and mature Leydig cell numbers were significantly reduced when compared with controls. Serum testosterone levels showed significant reduction after Tinospora extract feeding. Seminiferous tubule diameter, Leydig cell nuclear area as well as cross sectional surface area of Sertoli cells were reduced significantly when compared to controls. Biochemical parameters i.e. protein, sialic acid, glycogen contents of testes decreased significantly. Seminal vesicular fructose also depleted whereas, testicular cholesterol was elevated significantly followed by a reduction in testosterone levels. These results suggested antifertility effects of the stem extract of T. cordifolia in male rats.Item Cardiopulmonary actions of 1-isopropylamino-3-(3-tolyloxy)-2-propanol hydrochloride: a new adrenergic beta receptor antagonist.(1970-02-01) Madan, B R; Gupta, R S; Santani, D DItem Child survival and safe motherhood program in Rajasthan.(2006-01-31) Jain, S K; Chawla, Uma; Gupta, Neeru; Gupta, R S; Venkatesh, S; Lal, ShivOBJECTIVE: This study was planned to evaluate the MCH services, particularly immunization in rural areas of the poor-performing state of Rajasthan. METHODS: A community-based, cross-sectional survey using the WHO 30 cluster technique was carried out as a field exercise by participants of 9th Field Epidemiology Training Programme (FETP) course by National Institute of Communicable Diseases (NICD) in rural areas of Alwar district of Rajasthan. RESULTS: Less than one third (28.9%) of children, aged 12-23 months, were fully immunized with BCG, 3 DPT, 3 OPV and Measles vaccines; around a quarter (26.5%) had not received even a single vaccine (non immunized), and little less than half (44.5%) were found partially immunized. Around half of the eligible children were vaccinated for BCG (55.9%) and Measles (43.6%). Though nearly two-third (66.8%) were covered with first dose of DPT and OPV, but about one third of these children dropped out of third dose of DPT and OPV for various reasons. National Family Health Survey (NFHS) data also had revealed that BCG coverage was 64.3%; measles was 36.2%; and coverage by DPT 1, 2, 3 and Polio 1,2 and 3 were 64.4%, 57.0%, 46.6% and 77.5%, 71.1% and 54.4% respectively in rural areas. The main reasons for drop-out or non-immunization was "lack of information about the immunization programme" (41.3%). Though nearly all (more than 96%) of the children were immunized through Government established centers, but immunization cards/documents were made available only to 27.6% of children. CONCLUSION: The problem of low coverage and high drop-out rate of immunization could be overcome by creating awareness of the program and relevance of 2nd and 3rd doses of DPT and polio vaccines. Increasing community participation through intensive and extensive health education campaign should also be undertaken. Since most of the deliveries were done at home under the supervision of untrained midwives, training programme as well as involving them in IEC activities should be contemplated.Item Cholera outbreak in rural areas of southern Rajasthan.(2002-09-02) Gupta, R S; Meena, V R; Jain, D C; Datta, K KItem Community perception of mosquitos and mosquito control in some areas of urban Delhi and rural Alwar, Rajasthan.(1995-12-01) Kaul, S M; Verma, A K; Jain, D C; Gupta, R S; Dutta, AThere is little information regarding community perception of mosquitos and and their control in India. A qualitative study based on In depth discussions with the people in Urban Delhi, and rural Alwar was carried out in August-September, 1995. In the Ghazipur and Munirka areas of Delhi, 63 respondent groups with 171 head counts, and 59 respondent groups and 305 persons in Alwar were met. Community responses to uniform set of questions on mosquito types, seasonality, biting, breeding places, ongoing control activities, and methods of personal protection were recorded. Most people in the areas surveyed viewed mosquitos primarily as a biting nuisance, and secondarily as agents of disease and debilitators of health. In general the knowledge regarding mosquitos was deficient. An overwhelming tendency to attribute mosquitogenic conditions to the unsavoury features of one's physical environment was observed in both areas. The methods of personal protection and attitudes to organised control are discussed.Item Comparative efficacy of different plasma in the identification of coagulase positive staphylococci.(1978-10-01) Gupta, R S; Joshi, D V; Baxi, K KItem Comparative protein profiles of Salmonella and Escherichia coli.(2005-05-20) Gupta, Meenal; Sharma, V D; Gupta, R SProtein profiles of selected Salmonella serovars were compared with E. coli to identify genus specific protein(s) for Salmonella. The PDP formed of different Salmonella serovars were compared with E. coli O78 when subjected to SDS-PAGE yielded 11, 15, 15, 11 and 14 bands in S. Bareilly, S. Gallinarum, S. Typhimurium and S. Weltevreden and E. coli O78 respectively. The bands produced were compared with each other. It was found that S. Weltevreden shared 7 bands with E. coli O78, A protein of molecular weight 20.89 kDa was found in all Salmonella serovars, but not in E. coli O78 suggesting its genus specific attribute.Item Effect of adrenergic beta receptor blocking agents on cardiac output.(1970-04-01) Madan, B R; Gupta, R SItem Effect of alcohols on smooth & skeletal muscles.(1969-10-01) Madan, B R; Trivedi, H D; Gupta, R SItem Effect of ganglion blocking agents on spontaneous & adrenaline-induced ventricular ectopic tachycardia following coronary occlusion.(1970-07-01) Gupta, R S; Madan, B RItem Effect of propranolol and [4-(2-isopropylamino-1-hydroxyethyl) methanesulphonanilide hydrochloride] (MJ-1999) on pulmonary circulation.(1970-01-01) Madan, B R; Gupta, R SItem Effect of smoking on serum lipids and lipoproteins in healthy subjects, and patients of old myocardial infarction and hypertension.(1983-04-01) Garg, J P; Gupta, R S; Agrawal, M P; Bhandaril, V MItem Effects of short-term treatment of solasodine on cauda epididymis in dogs.(2002-02-08) Gupta, R S; Dixit, V POral administration (80 mg/kg body wt/day for 30 days) of solasodine (extracted and isolated from the berries of the Solanum xanthocarpum) to intact dogs significantly decreased the epithelial cell height of cauda epididymides. The cells became atrophic and the lumen was devoid of spermatozoa. Castration followed by the adminstration of solasodine further reduced the epithelial cell height in comparison to castrated controls. Concurrent treatment of solasodine along with testosterone propionate was unable to restore the normal epithelial lumen parameters. Total protein, sialic acid, glycogen and acid phosphatase activities were significantly reduced in solasodine treated cauda epididymides. These result suggest antiandrogenic potency of solasodine.Item An epidemiological study of anaemia in village Balupura in the area of U.H.T.C. at Adarsh Nagar, Ajmer.(1989-04-01) Gupta, A; Gupta, R S; Mathur, G MItem An epidemiological surveillance of acute flaccid paralysis in Alwar district.(2002-12-09) Gupta, R S; Meena, V R; Jain, D C; Khare, ShashiItem Evaluation of a sepsis screen for neonates.(1988-09-01) Bhandari, B; Tak, S K; Gupta, R S; Ramakrishnan, SItem Evaluation of pulse polio and routine immunisation coverage: Alwar District, Rajasthan.(1997-01-01) Bhattacharjee, J; Gupta, R S; Jain, D C; Devadethan,; Datta, K KDuring the last decade, India achieved 88% reduction in reported poliomyelitis incidence. However, absolute number of reported cases still remains high. As an added effort to eradicate the disease, the country observed its first National Immunisation Days (NIDs) on 9.12.95 and 20.1.96. The present study evaluates the performance of Alwar district, Rajasthan. Modified 30 cluster technique was used to collect information. Overall coverage in rural and urban areas was 89% and 91% respectively. Main source of information was television in urban and health staff in rural areas. Most of the respondents knew about the usefulness of such special activity and had favourable opinion about the facilities provided. Urban Alwar had 80% OPV3 coverage but, in rural area it was almost half. The reported coverage of NIDs and UIP was found to be conflicting with the study results. The existing "dose enumeration method" of calculating reported coverage was attributed to be the cause. The study emphasises the need to incorporate an in-built community-based evaluation of future NIDs and utilisation of such results for planning.Item Experimental model of staphylococcal osteomyelitis in dogs.(1989-09-01) Varshney, A C; Singh, H; Gupta, R S; Singh, S POsteomyelitis was induced in 45 male dogs by inoculating hemolytic strain of Staphylococcus aureus alone into the tibial marrow cavity. Clinical, radiological and bacteriological studies were conducted to evaluate the progress of disease up to 15 weeks. Clinical signs consisted of localized soft tissue swelling, pain, pyrexia and lameness which later developed an open wound with purulent exudation. Predominant radiographic features were extensive periosteal reaction, cortical lysis, new bone formation, frequent development of sequestrum and formation of localized abscess pockets in advanced cases. Staphylococci were recovered from the tibial marrow cavity for as long as 15 weeks after onset of the infection.