Browsing by Author "Gupta, B B"
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Item Albendazole in pulmonary hydatid disease.(1990-10-01) Talwar, D; Dhariwal, A; Gupta, B B; Sen Gupta, DA case of bilateral pulmonary hydatid disease successfully treated with six courses of albendazole obviating need for surgery is being reported. No side-effects of the drug were observed. Though the cysts ruptured initially but disappeared completely. No recurrence has been observed.Item Cimetidine in the treatment of duodenal ulcer.(1981-09-01) Misra, R C; Gupta, B B; Agarwal, S K; Gupta, P SItem Clinical spectrum of Budd-Chiari syndrome in Chandigrah with particular reference to obstruction of intrahepatic portion of inferior vena cava.(1972-03-01) Datta, D V; Saha, S; Singh, S A; Gupta, B B; Aikat, B K; Chhuttani, P NItem Congenital hypertrophic pyloric stenosis at birth.(1996-05-01) Sinha, C K; Gangopadhyay, A N; Sahoo, S P; Gopal, S C; Gupta, D K; Gupta, B BItem Controlled trial of twice a day versus once a day cimetidine therapy for duodenal ulcer.(1990-12-01) Aggarwal, R; Kochhar, R; Gupta, B B; Goenka, M K; Mehta, S KA randomized controlled trial was carried out to compare the efficacy of conventional 400 mg twice daily dose of cimetidine with single bedtime 800 mg dose, in 40 patients with endoscopically proven duodenal ulcer. At repeat endoscopy after four weeks of therapy, complete ulcer healing was achieved in 78% of patients on twice daily dosage and 79% of patients on single daily dosage. A more convenient single nocturnal dosage of cimetidine is as effective in the treatment of duodenal ulcer as a twice daily dosage in the Indian population.Item Dyschondroplasia (Ollier's disease). Report of two cases.(1974-08-01) Sodhi, J S; Ray, R N; Gupta, B BItem Effect of adrenal hormones on testis of the indian garden lizard Calotes versicolor.(1986-05-01) Thapliyal, J P; Gupta, B BItem Effect of adrenaline and nor-adrenaline on the oxidative metabolism of the Indian garden lizard Calotes versicolor.(1985-05-01) Gupta, B B; Thapliyal, J PItem Effects of propyl thiouracil induced hypothyroidism on annual body weight and testis development cycles of the Lal munia Estrilda amandava.(1986-06-01) Gupta, B B; Thapliyal, J PItem Effects of thyroidal, gonadal and adrenal hormones on tissue respiration of streaked frog, Rana limnocharis, at low temperature.(1990-01-01) Gupta, B B; Chakrabarty, PIn vivo and in vitro effects of thyroidal, gonadal and adrenal hormones were studied on the rate of liver and skeletal muscle respiration in both the sexes of R. limnocharis during active and inactive phases of the annual activity cycle. Triiodothyronine (L-T3) and thyroxine (L-T4) did not stimulate tissue (liver and muscle) respiration in any of the experiments irrespective of season, sex and temperature. Testosterone, estradiol and corticosterone stimulated O2 uptake significantly irrespective of season, sex and temperature. Adrenaline and nor-adrenaline also stimulated tissue respiration significantly during the winter month. Since the ambient temperature was low even during the active phase (max. temperature 21 degrees C), it seems that the frog might have developed tissue sensitivity for gonadal and adrenal hormones at low temperatures when thyroid hormones are calorigenically ineffective.Item Epidemiology of peptic ulcer in an urban community in Chandigarh.(1971-10-01) Sehgal, A K; Chhuttani, P N; Gupta, B B; Malik, K; Gupta, H DItem Experimental urolithiasis: Part IV--Morphological & biochemical alterations during stone growth.(1979-10-01) Thind, S K; Nath, R; Chakravarti, R N; Gupta, B BItem In vivo and in vitro effects of metabolic hormones on tissue respiration in toad, Bufo melanostictus during hibernation and active phase.(1995-08-01) Gupta, B B; Deka-Borah, HIn vivo and in vitro effects of L-T3, L-T4, estradiol, corticosterone, epinephrine and norepinephrine were studied on the rate of liver and muscle tissue respiration in B. melanostictus during hibernation and active phase under natural climatic conditions. Thyroid hormones were found to be calorigenic only during the active phase. Estradiol stimulated the respiratory rate directly during hibernation and indirectly during the active phase. Adrenal hormones invariably increased the respiratory rate of the tissues in all the experiments. On the basis of the present findings it can be concluded that the sensitivity of the tissues to various hormones is altered during the active phase and hibernation. The calorigenic action of thyroid hormones seems to be associated with activity-linked energy demand. Direct stimulation of tissue respiration by estradiol during hibernation may be of great adaptative significance. Due to their temperature-independent calorigenic action, adrenal hormones may be considered as emergency hormones for the regulation of the oxidative metabolism in the toad.Item In vivo effects of a single dose of norepinephrine and epinephrine on tissue respiration of hibernating and non-hibernating species of frogs.(1997-12-06) Gupta, B B; Mahanta, AIn vivo effects of a single dose of norepinephrine (NE) and epinephrine (EP) were studied on the rate of tissue (liver and skeletal muscle) respiration in Rana limnocharis (hibernating Sp.) and Rana cyanophlyctis (non-hibernating Sp.) during winter and summer months after 10 and 30 min, 1, 6, 12 and 24 hr of administration. During winter both NE and EP induced significant increase in the rate of tissues respiration only after 30 min after their administration in both the species and the stimulatory effect lasted up to 6 hr. During summer, however, NE and EP stimulated respiratory rate of tissues comparatively after a shorter lag period (10 to 30 min) in R. limnocharis than that of R. cyanophlyctis (30 min to 6 hr). These findings seem to suggest that NE and EP can stimulate tissue respiration very quickly, and, therefore, might be suitable as emergency hormones for instant/faster stimulation of energy metabolism in amphibians.Item Involvement of adrenal hormones in tissue respiration of sub-tropical hibernating and non-hibernating species of frogs.(1997-03-01) Gupta, B B; Mahanta, AEffects of norepinephrine (NE), epinephrine (EP), corticosterone and cortisol were studied both in vivo and in vitro on the rate of oxygen consumption of tissues (liver, skeletal muscle and kidney) of sub-tropical Indian frogs Rana limnocharis (a hibernating species) and Rana cyanophlyctis (a non-hibernating species) exposed to natural climatic conditions during winter and summer/rainy seasons. Further, the effects of NE and EP were also studied in vitro in the presence of specific beta- and alpha-adrenergic antagonists (propranolol and prazosin). NE, EP and corticosterone, when administered in vivo or in vitro, significantly stimulated the respiratory rate of the tissues of both the species irrespective of the seasons/temperature. Results suggest that NE, EP and corticosterone are directly involved in regulation of the energy metabolism of both hibernating and non-hibernating species of sub-tropical frogs. The calorigenic action of NE and EP seems to be mediated by both beta- and alpha-adrenergic receptors. However, the temporal involvement of beta- and alpha-adrenergic receptors seems to be tissue-dependent.Item Is it possible to achieve hundred per cent vaccination coverage for children below 5 years of age?(1999-08-01) Gupta, B B; Kushwaha, K PItem Leukocyte migration test against hepatitis B surface antigen in cryptogenic cirrhosis: a preliminary report.(1980-12-01) Gupta, B B; Misra, R C; Agarwal, S K; Saha, K; Gupta, P SItem The radiological dimensions of the skull, cephalic index and modulus index in the first four years of life.(1972-07-01) Walia, H K; Sodhi, J S; Walia, B N; Gupta, B BItem Risk factors and survival analysis of the esophageal cancer in the population of Jammu, India.(2012-04) Sehgal, S; Kaul, S; Gupta, B B; Dhar, M KObjective: To identify the risk factors of esophageal cancer and study their effect on the survival rates patients of Jammu region, India. Materials and Methods: Detailed information was collected on socio-demographic, dietary and clinico-pathological parameters for 200 case control pairs. Discrete (categorical) data of 2 independent groups (control and cases) were summarized in frequency (%) and compared by using Chi-square (χ2 ) test. The mean age of two independent groups was compared by independent Student's t-test. To find out potential risk factor (s), the variable (s) found significant in univariate analysis were further subjected to multivariate logistic regression analysis. The association of potential risk factors with patients survival (3-year overall survival) was done by Kaplan-Meier survival curve analysis using Log-rank test. A 2-tailed (a = 2) P < 0.05 was considered statistically significant. Results: Out of the 63 response parameters, seven were found highly significant on multivariate analysis. The mean (± SD) age was 56.74 ± 10.76 years, the proportions of males were higher than females, mostly illiterate and lower income group. Among dietary characteristics, snuff was highest (OR = 3.86, 95% CI = 2.46-6.08) followed by salt tea (OR = 2.53, 95% CI = 1.49-4.29), smoking (OR = 1.97, 95% CI = 1.18-3.30), sundried food (OR = 1.77, 95% CI = 1.10-2.85) and red chilly (OR = 1.76, 95% CI = 1.07-2.89). Probability of survival lowered significantly (P < 0.05 or P < 0.01 or P < 0.001) in those consuming tobacco in the form of snuff (Log-rank c 2 = 24.62, P = 0.000) and smoking (Log-rank c 2 = 5.20, P = 0.023) as compared to those who did not take these. Conclusions: The analysis finally established snuff (smokeless tobacco) as the most powerful risk factor of esophageal cancer in Jammu region, followed by the salt tea, smoking and the sundried food.Item Role of thyroidal and testicular hormones in regulation of tissue respiration in male air-breathing fish, Clarias batrachus (Linn.).(2000-07-24) Lynshiang, D S; Gupta, B BIn vivo and in vitro effects of thyroidal hormones (MIT, DIT, T3, T4), propyl thiouracil (PTU), testosterone and cyproterone acetate were studied on the rate of tissue (liver, muscle, kidney and brain) respiration of adult male C. batrachus during winter and summer/rainy seasons. Monoiodotyrosine (MIT) and diiodothyrosine (DIT) increased the respiratory rate in a dose-dependent and temperature-independent manner. Triiodothyronine (T3) and thyroxine (T4) stimulated tissue respiration during summer/rainy months but not during winter. PTU decreased tissue respiration during summer/rainy season and also at simulated low temperature. Testosterone invariably stimulated the rate of respiration of the tissues, while in vivo treatment with cyproterone acetate significantly decreased the metabolic rate of all the tissues. The findings suggest that in C. batrachus MIT and DIT may be more important than T3 and T4 at low temperature, endogenous thyroid hormones are involved indirectly in energy metabolism even during winter/at low temperature and testicular hormones are actively involved in the respiration.