Browsing by Author "Gupta, Mohit"

Now showing 1 - 11 of 11
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    Comparative Analysis of Indices of the Liver Function Tests in Patients with and without Non- Alcoholic Fatty Liver Disease at a Teaching Hospital in Hapur
    (Ibn Sina Academy of Medieval Medicine & Sciences, 2019-09) Kumar, Ujjwal; Gupta, Mohit; Chaudhary, Prabhat; Kem, Anil Kumar; Sinha, Vivek
    Background: Non-Alcoholic fatty liver disease (NAFLD) has become a worldwide health concern with increase in the global incidence of obesity and it is now considered the hepatic component of the metabolic syndrome. Aims and Objective: The study’s aim was to compare the indices of the Liver Function tests in compensated chronic liver disease patients with and without NAFLD. Materials and Methods: A total of 100 consecutive patients with compensated chronic liver disease were recruited into the study. A structured questionnaire was administered to obtain relevant socio-demographic data. NAFLD was diagnosed based on clinical, biochemical, ultrasonographic and in a few histological features. The Adult Treatment Panel III criteria were used to identify patients with the metabolic syndrome. Results: In our study, 100 participants were recruited into study. 40 out of 60 patients (67%) showed grade-1 fatty liver findings and 20 out of 60 patients (33%) showed grade-2 fatty liver. Approximately 19% had fatty liver finding. The mean (SD) age of persons with NAFLD was 45.12 (±8.07) years compared  to 47.49(±11.79) years for persons without NAFLD. The difference was not statistically significant (p=0.2). Body mass index (BMI), central obesity (waist circumference), fasting  blood sugar, blood pressure, total cholesterol and triglycerides were significantly higher in  the NAFLD group (p= <0.05) respectively.  Conclusion: Indices of the deranged Liver functions were more prevalent in persons with NAFLD. It is recommended that patients with NAFLD be screened for metabolic syndrome and appropriate therapy instituted to decrease the risk of both hepatic and cardiovascular complications.
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    Giant Fronto-parietal Encephalocele: A rare case report.
    (2015-04) Dalal, Poonam; Rattan, K N; Gupta, Mohit; Rattan, Ananta
    Although encephaloceles are common, but giant encephaloceles are rare with only few published short series and are mostly described in occipital location. Giant frontal encephaloceles are very rarely reported with only four published case reports in the world literature and giant encephalocele in fronto-parietal region has not been reported till date. Herein, we report a rare case of giant frontoparietal encephalocele in a six month old girl.
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    Importance of adipocere in determining the cause of death.
    (2011-07) Gupta, Mohit; Jain, Gaurav V
    Adipocere (term coined by Fourcroy in 1789) also known as corpse wax or grave wax or mortuary wax , derives its name „adipo‟ and „cire‟ meaning the affinity with both fat and wax. It is a late but sure sign of death. It becomes extremely difficult for crime investigators to determine the cause of death in bodies in an advanced stage of decomposition. In such instances, changes like the formation of adipocere and mummification help to preserve certain features and injuries that aid in the determination of identity and in determination of the cause of death of the body. This paper highlights a case in which adipocere was developed and its significance in determining the cause of death. However, decomposition changes like the formation of adipocere, helps to preserve injuries which can aid the forensic experts in opining about the cause of death and hence thereby assisting the law enforcers in administering of justice.
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    Interpretation: a confounding factor.
    (2016-04) Gupta, Mohit
    With reference to the article “Passive euthanasia in India: a critique”, authored by Ms Rohini Shukla and published online on August 5, 2015, I would like to make a few comments and highlight the following points. First, the author notes that Section 309 IPC has been decriminalised. This is not so since there has neither been any amendment to the IPC, nor has any ordinance been passed regarding the matter.
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    MRKH syndrome: Psychological disturbances and suicide.
    (2012-01) Gupta, Mohit; Kharb, Varsha
    The Mayer- Rokitansky-Küster-Hauser (MRKH) syndrome has been known to be associated with psychological abnormalities. However, hardly any case has been reported of suicide by an individual suffering from such syndrome, as per the author‘s knowledge. A 19 year old female was brought to Safdarjung hospital mortuary for post mortem examination. After eliciting a detailed history from the relatives of the deceased, going through the previous investigation reports and after post mortem examination it was confirmed that the deceased was suffering from MRKH syndrome. The mental stress associated with the diseased state resulted in the female committing suicide by ingesting some unknown substance. Emotional support forms the basis of treatment in such cases. Surgical treatment is also employed in some cases so as to help them lead normal sexual life. This paper deals with the pathology and psychological profile of the patient suffering from this syndrome and the therapeutic options that may be considered to ameliorate the stress associated with the disease.
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    Parotid sialolithiasis with Stenson’s duct stricture: a rare case report
    (Medip Academy, 2020-04) Raza, Mohammed; Gupta, Mohit
    Sialolithiasis is the most common disease that affects the major salivary glands and occurs mainly in the submandibular gland (80-90%), and to a lesser degree in the parotid gland (5-20%). In literature many papers have been published regarding the parotid calculi and their treatment. However, data on salivary duct strictures management is less with variable opinion. We present a case of 45-year-old female with swelling of right parotid for 6 months, USG showed duct calculi with sialadenitis and sialogram showed large duct calculi with high grade strictures. Duct calculi was removed by intra-oral approach and parotidectomy was done as endoscopic management of strictures failed. This was highlighted case as parotid duct calculi along with high grade strictures are rare.
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    Portopulmonary hypertension in a patient of autoimmune hepatitis.
    (2005-04-19) Hira, H S; Gupta, Mohit; Tyagi, S K
    A 35-year-old women presented with breathlessness and features suggestive of pulmonary hypertension. Further investigations revealed that she had autoimmune hepatitis and both portal and pulmonary hypertension. Pertinent literature is reviewed.
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    Positional asphyxia: An opinion of exclusion.
    (2011-07) Yadav, Abhishek; Gupta, Mohit; Kumath, Manish; Panwar, Mamta; Kishore, Upender
    The process of normal respiration depends upon three vital components i.e. a patent airway, an intact surface for gas exchange and a normally working ventilatory apparatus. The positional asphyxia has been defined as asphyxia caused due to unusual position of the body which interferes with the breathing and thus pulmonary ventilation. We are reporting a case of an adult female, who under the influence of alcohol positioned herself in such a way which led her to death due to positional asphyxia. The internal and external findings were non-specific. Therefore the exclusion criteria were used to conclude that the death was due to positional asphyxia. The cases of positional asphyxia are difficult to diagnose because of the absence of any specific external findings. The internal findings found in such cases are also non-specific and can be found in any case of an asphyxial death.
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    Quality of Life in Symptomatic HIV Infected Children.
    (2013-12) Gupta, Mohit; Nanda, Sanjiv; Kaushik, Jaya Shankar
    We conducted a case control study to compare the quality of life (QOL) in 40 cases of HIV infected children and 40 demographically matched controls with other chronic ailments at a referral hospital in Northern India. Quality of life among HIV infected children was significantly better in psychosocial (P=0.008), emotional (P=0.001) and school (P=0.039) functioning. Factors including age (P=0.07), gender (P=0.44), socioeconomic status (P=0.99), clinical (P=0.18) and immunological staging (P=-0.91) of HIV infection did not significantly influence QOL scores. Hence, quality of life in HIV infected children of North India was better than those suffering from other childhood chronic illness.
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    A retrospective study of serious adverse drug reactions and associated risk factors in a tertiary care hospital
    (Medip Academy, 2020-01) Shenoy, Smita; Gupta, Mohit; Holla, Sadhana; Home, Madhurima; Thanusubramanian, Harish
    Background: Serious adverse drug reactions (ADRs) cause physical, psychological and economic harm to patients and society. This study was undertaken to understand serious ADRs in a tertiary care hospital and risk factors associated with it.Methods: The serious adverse reactions that occurred over a one-year period were assessed. The serious adverse drug reactions, action taken, outcome, predictability, suspect drug, causality, patient demographics and risk factors for the reaction was collected. Chi-square test was applied for observing relationships of predisposing factors for serious ADRs.Results: Out of a total of 984 reported adverse drug reactions, 94 (9.55%) were serious. Hematological disorders (41.05%) were the common serious ADRs followed by electrolyte disturbances (18.94%). Anticancer agents were the suspect drugs for majority of serious ADRs. Serious ADRs contributed to 39 (0.05%) admissions in the hospital. Recovery occurred in 97.87% of the patients. The causality was possible in 91.48% (n=86) and probable in 8.51% (n=8) of the serious adverse drug reactions. Males, patients even with a single concomitant disease and those with more than 2 concomitant medications were at increased risk (p<0.05) for developing serious ADRs.Conclusions: Serious ADRs are a significant problem in health care. Measures should be taken to detect and treat them at the earliest to reduce suffering of the patient.
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    Subclavian artery thrombosis--management with thrombolysis and angioplasty.
    (2004-09-13) Dave, Bhavesh; Bhatt, Naveen; Gupta, Mohit; Khalasi, Yogendra; Balasubramanya, K S
    A case of acute thrombotic occlusion is presented in a chronically stenosed subclavian artery with subclavian steal phenomenon noted on colour Doppler study and angiography. Because of economic constraints, thrombolysis with angioplasty was done instead of stenting. The patient is on follow-up for the past one year showing considerable improvement. The present case report confirms the efficacy of angioplasty as a suitable option in patients, who cannot afford to have a stent.