Browsing by Author "Ghosh, Ranajoy"

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    Molecular profiling of tumours by immunohistochemistry.
    (2007-11-14) Sarkar, Chitra; Das, Prasenjit; Ghosh, Ranajoy
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    Polypoid Multifocal Ileo-Colonic Amyloidoma Masquerading Malignancy - A Rare Case Report
    (Atharva Scientific Publications, 2019-03) Halder, Aniket; Ghosh, Ranajoy; Ray, Sukanta
    Amyloidosis is a group of disorders characterized by extracellular deposition of a proteinaceous homogenous eosinophilic hyaline substance known as amyloid. Congo red staining is a specific stain for amyloid which shows an apple-green birefringence on polarized microscopy. Amyloid deposition can be systemic or localized. Primary amyloidosis (also known as AL amyloidosis) is the most common form of amyloidosis characterized by generalized deposition of excess immunoglobulin light chains. It is associated with an underlying plasma cell dyscrasia and has the maximum gastrointestinal (GI) involvement. Secondary amyloidosis is characterized by deposition of acute-phase reactant - serum amyloid A protein (also known as AA amyloidosis) and it is associated with infectious, inflammatory, or less commonly, neoplastic disorders. Renal dysfunction is the most common symptom of AA amyloidosis at diagnosis. Amyloidosis presenting as a localized mass is known as amyloidoma. Amyloidoma of the GI system is a rare finding in the absence of any systemic involvement. We report a rare case of localized multifocal polypoid amyloidoma in the lower GI tract, which masquerades as malignancy
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    Potter’s sequence: A story of the rare, rarer and the rarest.
    (2015-01) Sarkar, Saurav; DasGupta, Shatavisha; Barua, Madhumita; Ghosh, Ranajoy; Mondal, Kaushik; Chatterjee, Uttara; Datta, Chhanda
    Potter’s syndrome is a rare condition affecting one in 2000-5000. We present here two autopsy cases of Potter’s syndrome, with the rare fi nding of discoid adrenals and the even rarer fi nding of in situ neuroblastoma in one of the cases.
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    Primary hepatic leiomyosarcoma masquerading as focal nodular hyperplasia of liver: A wolf in sheep’s clothing
    (Wolters Kluwer – Medknow, 2024-12) Ghosh, Ranajoy; Halder, Aniket; Nim, Ranjit K.; Ray, Sukanta; Chatterjee, Uttara
    Primary hepatic leiomyosarcoma is a rare hepatic malignancy which requires exclusion of other primary site of origin. Clinical presentation and imaging of this tumor is nonspecific and mimics many other hepatic neoplasms. A 62?year?old female patient presents here with right hepatic mass with insidious onset and radiological features favoring a benign solid lesion suggestive of focal nodular hyperplasia. On right hepatectomy, an encapsulated mass identified about 11 cm in maximum dimension with pushing margin and central scar?like area. Histopathological examination reveals a spindle cell tumor and panel of immunohistochemical markers is required to distinguish it from other morphological mimickers. Diagnosis of primary hepatic leiomyosarcoma requires histopathology along with immunohistochemical examination. It is thus advisable to do preoperative biopsy with immunohistochemistry in all patients having atypical imaging and clinical features.
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    Sacrococcygeal teratoma with ectopic immature renal tissue.
    (2015-01) DasGupta, Shatavisha; Ghosh, Ranajoy; Das, Ram Narayan; Chatterjee, Uttara