Browsing by Author "Dua, Ruchi"

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    Exfoliative Dermatitis to all four first line oral antitubercular drugs.
    (2010-01) Dua, Ruchi; Sindhwani, Girish; Rawat, Jagdish
    Exfoliative dermatitis to all four first line drugs singly or rarely in combination has been reported. Here we report a rare case of pulmonary tuberculosis with exfoliative dermatitis to all four oral first line antitubercular drugs. (Rifampicin, Isoniazid, Ethambutol, Pyrazinamide). To the best of our knowledge, this is the first such case.
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    Perianal tuberculous ulcer in an immuno-competent patient.
    (2009-10) Rawat, Jagdish; Verma, R K; Sindhwani, Girish; Dua, Ruchi; Negi, Geeta
    Perianal tuberculosis, without the presence of any previous or active pulmonary infection, is extremely rare. A wide range of differential diagnosis for perianal ulcers might be one reason for a possible delay in establishing this diagnosis.
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    Primary multi-drug resistant tubercular lymphadenitis in an HIV infected patient.
    (2009-07) Rawat, Jagdish; Sindhwani, Girish; Dua, Ruchi
    Cervical lymphadenitis is a common extra-pulmonary manifestation of tuberculosis in HIV patient; nevertheless, it seems that the primary Multi Drug Resistant (MDR) involving extra-pulmonary site is uncommon. We report a case of tubercular lymphadenitis by multi-drug resistant strain of Mycobacterium tuberculosis in an HIV seropositive male, which has not been reported so far in literature.
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    Test-retest Repeatability and Minimal Detectable Change of 1-minute Sit-to-Stand Test for the Ability to Detect Exercise-induced Oxygen Desaturation in Patients with Interstitial Lung Diseases
    (Jaypee Brothers Medical Publishers Pvt. Ltd., 2024-06) Panjiyar, Vickey; Sharma, Prakhar; Banerjee, Saikat; Sanjan, Ganesh; Bahurupi, Yogesh A; Joshi, Narayan; Dua, Ruchi; Saini, Lokesh K; Mishra, Mayank; Sindhwani, Girish
    Background: While methods like the 6-minute walk test, shuttle walk test, and cardiopulmonary exercise testing (CPET) are available to assess exercise limitation, they need a large space to perform/advanced lab settings which makes 1-minute sit-to-stand test (1STST) a feasible option in office practice. Data on test-retest reliability and the minimal detectable change (MDC) of 1STST is lacking in both national and international literature. Materials and methods: In this prospective observational study, our objective was to assess test-retest reliability and the MDC of the 1STST in patients with ILD and to determine the correlation of 1STST with the severity of interstitial lung disease (ILD) by spirometry and mGAP index. Results: A total of 65 ILD patients underwent 1STST during the study duration. The mean number of repetitions during the test retest 1STST and were 20 ± 6 and 21 ± 6 respectively (p = 0.029). The intraclass correlation coefficient (ICC) between a number of repetitions during 1STST and retest 1STST was 0.914 with SEM of 1.551 repetitions and a MDC of 4 repetitions. Statistically significant poor correlation was observed between test and retest 1STST repetitions with diffusion capacity of lung for carbon monoxide (DLCO) predicted z score (r = 0.428 and p = 0.006). modified gender age lung physiology index score (r = –0.195, p = 0.142), SpO2 drop (r = –0.301; p = 0.013), BMI of patients (r = –0.287; p = 0.02), and baseline hemoglobin level (r = –0.095; p = 0.504) had a negative poor correlation with number of repetitions during 1STST. Conclusion: The 1-minute sit-to-stand test is a valuable tool for detecting exercise-induced desaturation in ILD patients, showing reliability and a MDC of approximately 4 repetitions.