Browsing by Author "Chaturvedi, P"

Now showing 1 - 20 of 92
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    Achondrogenesis-I.
    (1985-06-01) Tandan, R; Bhatia, B D; Chaturvedi, P; Dubey, A P; Mathur, N B; Dhakate, S
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    Acinetobacter septicemia with gangrene of toes in a neonate.
    (1984-09-01) Bhatia, B D; Mathur, N B; Chaturvedi, P; Dubey, A P
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    Acute laryngeal stridor--controversies in current management.
    (1992-09-01) Chaturvedi, V N; Chaturvedi, P
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    Acute paralytic poliomyelitis in rural Maharashtra.
    (1992-06-01) Chaturvedi, P; Banerjee, K S; Bharambe, M S
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    Analysis of blood-culture isolates from neonates of a rural hospital.
    (1989-05-01) Chaturvedi, P; Agrawal, M; Narang, P
    All blood culture reports obtained from newborns admitted in a neonatal care unit during 1983-87 were reviewed to determine the current bacteriological profile of neonatal septicemia. A total of 1160 neonates of high risk category or having clinical features suggestive of septicemia were subjected to blood culture study during this period. The culture positivity rate was 73%. Of these, 24.9% cultures were polymicrobial. Among the 1059, growths obtained, 60.1% were Gram negative, with Klebsiella, E. coli and Pseudomonas as the commonest pathogens. In Gram positive group, coagulase negative Staphylococci were most frequent, constituting 24% of the total isolates. An increasing incidence of coagulase positive Staphylococci and Pseudomonas infections was observed in recent years. Another significant finding was a comparatively high prevalence of Group D beta hemolytic isolates among streptococcal growths, with S. fecalis as the single commonest streptococci isolate.
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    Antibacterial effects of azadirachta indica leaf and bark extracts in clinical isolates of diabetic patients.
    (2011-01) Chaturvedi, P; Bag, A; Rawat, V; Jyala, N S; Satyavali, V; Jha, P K
    Background: Antibacterial activities of crude Azadirachta indica (neem) bark and leaf extracts were investigated in bacterial species isolated from clinical samples of diabetic individuals. Methods and Material: Nine different dilutions of methanolic bark and leaf extracts were tested for this purpose in agar well diffusion method. Results: Both the extracts were active against Gram positive as well as Gram negative strains. Zones of inhibition produced by different bacteria for different concentrations were summarized by linear regression. Highest activities were exhibited for coagulase negative Staphylococcus (CONS) by both bark and leaf extracts, Y = 16.95 + 0.19X and Y = 18.90 – 0.70X, respectively. Conclusions: Results indicate that exhaustive studies involving identification of specific compounds in neem extracts and testing their activities in diabetic samples would be worthwhile considering steep emergence of multidrug resistant species in diabetic infections and infections in general.
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    Antioxidant property of Smilex china Linn.
    (2001-11-22) Tripathi, Y B; Upadhyay, A K; Chaturvedi, P
    Smilex china Linn. (Smilacaceae Syn Liliaceae) has special pharmacognostic feature as its root is multiseriate, with sclerenchymatic pericycle. The alcoholic extract of rhizome of S. china shows significant protection against FeSO4 induced lipid peroxidation in rat liver homogenate, but has no effect on the rate of oxidation of reduced glutathione. This fraction scavenges the superoxide and hydroxyl radicals, but the effect was more towards the removal of superoxide than that of hydroxyl radicals. Thus it could be concluded that rhizome of S. china has strong antioxidant property.
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    Arthritis in children: an occult manifestation of Bancroftian filariasis.
    (1993-11-01) Chaturvedi, P; Gawdi, A M; Parkhe, K; Harinath, B C; Dey, S K
    A form of unexplained arthritis, not attributable to known causes, seen in children (0-14 yrs) in this endemic zone of Bancroftian filariasis was investigated for its association with filariasis. Nineteen cases of undiagnosed arthritis were screened for filarial IgG antibodies to Wuchereria by Stick Enzyme Linked Immunosorbent Assay (ELISA). All had large joint involvement, the commonest joint affected being the knee joint. Involvement was monoarticular in 10 and binarticular in 9. Joint pain was present in 18 and effusion in 12. Five patients had recurrent episodes. Sixteen (84.2%) showed filarial antibodies of which only one (5.3%) was microfilaraemic. Patients with classical filariasis (16), disease controls (10), endemic normals (15) and non-endemic normals (10) were also subjected to ELISA to ascertain the sensitivity and specificity of the technique. Fifteen (93.8%) cases of classical filariasis and 1 (6.7%) of endemic normal were antibody positive, whereas none of disease controls and non-endemic normals had filarial antibodies. Nine cases of filarial arthritis reviewed after a course of Diethylcarbamazine showed satisfactory response to treatment.
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    Asphyxiating nasopharyngeal teratoma at birth.
    (1985-04-01) Mathur, N B; Raizada, R M; Bhatia, B D; Dubey, A P; Chaturvedi, P; Dhakate, S
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    Assessment of endocrine response of Inula racemosa in relation to glucose homeostasis in rats.
    (1995-09-01) Tripathi, Y B; Chaturvedi, P
    Alcoholic extract of the root of I. racemosa lowers blood glucose and enhances liver glycogen without increasing plasma insulin in rats. There is also no increase in degree of degranulation of the beta cells of pancreas. In similar conditions it does not show any effect on activity of adrenal gland. However, thyroid gland undergoes activation at the later stage (delayed response). It appears that hypoglycemic response of I. racemosa is not due to enhanced secretion/synthesis of insulin; the action may be at the peripheral level by potentiating the insulin sensitivity.
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    Assessment of hearing in small children.
    (1980-10-01) Chaturvedi, V N; Chaturvedi, P
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    Ataxia telangiectasia.
    (1999-12-04) Datta, V; Chaturvedi, P
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    Bacterial flora in chronic tonsillitis.
    (1989-01-01) Chaturvedi, V N; Methwani, A; Chaturvedi, P; Narang, P
    A study of aerobic and anaerobic bacterial flora in chronic tonsillitis revealed a total of 59 isolates. Aerobic flora from the surface swab was found in 80%, from the core of the tonsil in 92% and from both the surface and the core in 68% of the cases. There were 30 aerobic isolates from the surface and 29 isolates from the core. Mixed flora were present from the surface and the core in 10 and 7 cases, respectively. Pathogens were seen in 36% of the cases from the surface and in 40% from the core. There was no significant difference in the nature of aerobic flora from the two sites. Anaerobic flora were cultured from the core only and were seen in 20% of cases. There were a total of 7 isolates. In 16% cases it was associated with aerobic flora. The common aerobes were Beta hemolytic streptococcus (16%) and Staphylococcus coagulase positive (12%) and common anaerobes were Peptostreptococcus (16%) and Veillonella parvula (4%). There was no consistent pattern of combination of aerobes and anaerobes in chronic tonsillitis.
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    Bell's palsy.
    (1995-09-01) Chakravarti, A; Singh, M M; Chaturvedi, V N; Chaturvedi, P
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    Bulging anterior Fontanel after DPT vaccination.
    (1994-01-01) Chaturvedi, P; Bannerjee, K S; Gawdi, A
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    Candida colonization in preterm babies admitted to neonatal intensive care unit in the rural setting.
    (2006-10-23) Mendiratta, D K; Rawat, V; Thamke, D; Chaturvedi, P; Chhabra, S; Narang, P
    PURPOSE: Candida colonization in neonates results in significant morbidity and mortality. The purpose of this study was to determine colonization of Candida spp. in preterm babies and identify the risk factors. METHODS: Swabs from oral, rectum, groin and umblicus of 103 preterm and 100 term neonates were obtained within 24 hours of birth, day three, day five, day seven and thereafter every week till the neonate was admitted in the neonatal intensive care unit (NICU). Swabs were also collected from the mother's vagina prior to delivery. Twice every month, air of the NICU was sampled by settle plate and swabs were collected from the hands of health care workers and inanimate objects of NICU. Identification and speciation was done by standard methods. Antibiotic sensitivity was studied against amphotericin B, ketoconazole and fluconazole by disk diffusion method. RESULTS: Colonization with Candida was significantly higher in preterms. Earliest colonization was of oral mucosa and 77.1% of the preterms had colonised at various sites by the first week of life. Significant risk factors in colonized versus non-colonized preterms were male sex, longer duration of rupture of membranes (DROM), administration of steroids and antibiotics and vaginal colonization of mothers, whereas those in preterms versus terms were low birth weight and gestational age. C. albicans was the commonest species, both in the colonized preterms (45.9%) and vagina of mothers. Resistance was seen to fluconazole and ketoconazole only. No Candida spp. was isolated from health care personnel or environment. CONCLUSIONS: Colonization of preterms by Candida is a significant problem in NICU and the significant risk factors observed in colonized preterms were male sex, longer DROM, administration of steroids and antibiotics and vaginal colonization of mothers.
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    Cetuximab with radiotherapy in patients with loco-regionally advanced squamous cell carcinoma of head and neck unsuitable or ineligible for concurrent platinum-based chemo-radiotherapy: Ready for routine clinical practice.
    (2011-04) Agarwal, J P; Gupta, T; Kalyani, N; Budrukkar, A; Laskar, S G; Murthy, V; Kumar, P; Narohna, V; Pai, P; Chaturvedi, P; D'cruz, A K
    Purpose : To report outcomes of cetuximab concurrent with radiotherapy in advanced head-neck cancer unsuitable for platinum-based chemo-radiotherapy. Materials and Methods : Retrospective chart review of 37 patients treated with cetuximab and radiotherapy at a comprehensive cancer centre. Results : Median age of study cohort was 59 years. Thirty four (92%) patients had advanced stage disease (stage III-IV). Reasons for ineligibility for platinum included impaired creatinine-clearance, old age, and/or co-morbidities. Thirty-two (86%) patients completed planned radiotherapy without interruption; 29 (80%) patients received ≥6 cycles of cetuximab. Fifteen patients (40.5%) developed ≥grade 3 dermatitis; 9 patients (25%) experienced ≥grade 3 mucositis. At a median follow-up of 16 months, the 2-year loco-regional control, disease-free survival, and overall survival was 35.5%, 29.5%, and 44.4% respectively. Stage grouping and severe dermatitis were significant predictors of outcome. Conclusions : Cetuximab concurrent with radiotherapy is a reasonable alternative in advanced head-neck cancer patients with acceptable compliance and outcomes, but higher skin toxicity.
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