Browsing by Author "Broor, S L"
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Item Achalasia: drugs, balloon or the surgeon's knife!(1991-04-01) Broor, S LItem Acute effects of histamine H1- and H2-receptor antagonists on pituitary hormone secretion in man.(1980-05-01) Kaul, K; Dash, R J; Sialy, R; Broor, S LItem AIDS cholangiopathy.(1998-07-08) Misra, A; Gupta, R; Broor, S L; Puri, S KA 45-year-old man presented with diarrhea and profound weight loss over one year. His serum alkaline phosphatase was raised and ultrasonography showed dilated intrahepatic biliary ducts and upper part of common bile duct (CBD). ERCP showed papillary stenosis, dilated CBD, stricture at the confluence and saccular dilatation of the left intrahepatic biliary ducts. He was found HIV-positive. Duodenal biopsy, rectal biopsy and stool examination could not identify any opportunistic organism.Item Albendazole: a new broad spectrum anthelmintic for treatment of intestinal helminthiasis.(1986-10-01) Broor, S L; Bassi, S S; Broor, SItem Aspirin and the gastric mucosa.(1984-10-01) Broor, S L; Kalra, O PItem Benign strictures of esophagus.(1988-10-01) Kumar, A; Broor, S LItem Cimetidine in treatment of duodenal ulcer: results of a short term double blind study.(1979-09-01) Grewal, G S; Broor, S L; Mehta, S K; Chuttani, P NItem Clinical and endoscopic features of hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease) in India.(1996-01-01) Puri, A S; Kumar, N; Mishra, A; Gupta, R; Lamba, G S; Rawal, K K; Broor, S LHereditary hemorrhagic telangiectasis (HHT) is an autosomal dominant disease characterized by recurrent epistaxis and telangiectasia of the skin and mucous membranes. Most reports of HHT are from Europe and N. America. In this report of 7 patients from India we postulate that increased skin pigmentation in Asians and Negroids masks the cutaneous manifestations of the disease but without any discernible effect on mucosal lesions. The median hemoglobin value in these patients was 4 g/dl. Endoscopic lesions in the stomach or duodenum were detected in six patients. Most patients in our report (5/7) presented with a chronic iron deficiency anaemia. The treatment of HHT is mainly supportive although our preliminary data shows that low dose ethinyl estradiol therapy decreases transfusion requirement in these patients.Item Clinical and etiological profile of acute viral hepatitis.(1992-05-01) Singh, V; Dubey, A P; Sachdev, H P; Broor, S L; Sebastion, M; Puri, R KThere is a paucity of data on the incidence of sporadic viral hepatitis in Indian children. Clinical, biochemical and etiological profile of 54 patients with acute viral hepatitis was evaluated. Of these, 32 (59.25%) patients had Hepatitis A, 18 (33.33%) had NANB, 2 (3.7%) had Hepatitis B and 2 (3.7%) concurrent Hepatitis A and B infection. It was not possible to distinguish the etiological agents on the basis of the clinical and biochemical profile. Fulminant hepatitis was documented in 8 (14.8%) cases. Children with NANB infection were at a greater risk (p less than 0.05) of developing fulminant hepatitis as compared to Hepatitis A infection.Item Colopathy in portal hypertension.(1992-10-01) Bhatia, V; Broor, S LItem Combination of anticholinergic agent and H2 receptor antagonist in duodenal ulcer treatment--a randomized, double blind multicenter study.(1993-07-01) Agrawal, B K; Suman, A; Kumar, A; Broor, S L; Rajasambandam, P; Palaniswamy, K R; Mohan, A T; Gupta, J PBACKGROUND: The acid suppressive abilities of H2 receptor antagonists and anticholinergics have been claimed to be additive. METHODS: A multicenter, double-blind, randomized trial comparing ranitidine (150 mg) plus propantheline bromide 15 mg at bedtime to ranitidine 300 mg alone at bedtime was conducted in 161 patients with endoscopically confirmed uncomplicated duodenal ulcer. RESULTS: After six weeks of therapy, ulcer healing rates in the two groups were comparable ie 80% in the combination group (ranitidine + propantheline) and 79.4% in the ranitidine group. Pain relief after one, two and four weeks of treatment was also comparable in the two groups. Side effects to drugs were minor and comparable in both the groups. CONCLUSION: A combination of 150 mg ranitidine and 15 mg propantheline bromide is as efficacious as 300 mg ranitidine in inducing healing of uncomplicated duodenal ulcers, with similar side-effects but at greatly reduced cost.Item A comparative study of 50% alcohol and ethanolamine oleate for oesophageal sclerotherapy.(1988-10-01) Vij, J C; Kumar, N; Kumar, A; Anand, B S; Broor, S LItem Comparison of ranitidine 300 mg nocte and 150 mg twice daily in the treatment of duodenal ulcer.(1988-04-01) Kumar, N; Anand, B S; Broor, S LItem A comparison of ranitidine with cimetidine in short term treatment of duodenal ulcer.(1985-01-01) Broor, S L; Gilhotra, R; Kalra, O P; Mehta, S K; Nanda, V; Sharma, B KItem Corrosive injury to the upper gastrointestinal tract.(1993-10-01) Lahoti, D; Broor, S LCorrosive injury to the UGI tract is a common problem and has a wide spectrum of presentations. Unlike in the West, where lye ingestion is more frequent, corrosive injury in India is more commonly due to acids. Depth of the injury is the most important factor which determines the outcome. Endoscopy done soon after corrosive ingestion is safe and is very helpful in assessing the extent and severity of injury and in planning proper management of these patients. At present no therapy has been proven to be effective for prevention of stricture formation. Endoscopic dilatation seems to be the treatment of choice for management of most esophageal strictures with very good short and long term results. Surgery should be considered only when dilatation fails.Item Desquamative interstitial pneumonia.(1977-04-01) Broor, S L; Kaur, U; Datta, B N; Sapru, R PItem Does Helicobacter pylori cause gastric cancer?(1992-04-01) Lahoti, D; Broor, S LItem Duodenal angiomyolipoma: a case report.(2007-07-22) De Padua, Michelle; Gupta, Noopur; Broor, S L; Govil, DeepakThe authors present a case of duodenal angiomyolipoma. Angiomyolipoma is a benign neoplasm, the most common site being the kidney. Extrarenal angiomyolipomas are rare. Only one case of duodenal angiomyolipoma has been reported. A 66 year old man presented with GI bleeding for two years. Endoscopy revealed a duodenal polyp which on histopathology revealed features of angiomyolipoma. On immunohistochemistry, smooth muscle component was positive for Smooth Muscle Actin. HMB-45 showed mild focal positivity. Patient had no history of tuberous sclerosis. Surgical excision of angiomyolipoma is usually curative with rare cases of local recurrence.Item Duodenal ulcer: maintenance treatment with cimetidine.(1983-07-01) Broor, S L; Shrestha, G P; Mukewar, S V; Augustine, P; Mehta, S K; Sharma, B KItem Effect of clofazimine: detailed studies of small intestine functions.(1985-04-01) Bhasin, D K; Kumar, B; Broor, S L; Kaur, S; Malik, A M; Mehra, S KTwenty one patients of leprosy were studied for gastrointestinal symptoms and submitted to detailed intestinal absorption tests and jejunal biopsy before and after the institution of Clofazimine therapy. Fifteen patients were administered 100 mg orally daily for 3 months, while six patients with ENL received 300 mg of the drug for 6 weeks initially and then 100 mg daily. Mild diarrhoea and abdominal symptoms occurred in four patients, fecal fat excretion increased in one patient but Schilling's and d-Xylose tests did not alter. No significant changes were produced by Clofazimine therapy in jejunal mucosa. Clofazimine crystals were seen in the lamina properia of one patient, the overlying mucosa was normal. No correlation was found between the abnormality in mucosal pattern, crystal deposition, absorption parameters or symptomatology and doses of drug taken.
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