Browsing by Author "Behera, JR"

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    Comparative Outcome Analysis of Greenlight Laser Prostatectomy Versus Bipolar TURP In Benign Prostatic Hyperplasia
    (Society for Scientific Research, 2024-07) Mahapatra, SK; Nayak, AK; Behera, JR; Mohapatra, B; Panigrahi, S.
    Background: Benign prostatic hyperplasia is a disease of the prostate in ageing males. Bipolar TURP is gaining more acceptance due to decreased complications. The introduction of Photoselective Vaporisation of Prostate (PVP) or Green light Laser has emerged as a safer alternative to Bipolar TURP. Methods: An unbiased cohort research comprising ninety patients (greenlight laser 45, bipolar TURP 45) between November 2020 to October 22 with BHP older than fifty years old with prostate of size 40–70 gm to compare the greenlight laser and bipolar TURP clinical outcomes. Results: The patients' mean age in the Greenlight group was 69.756 years, with an SD of 6.5372, while their mean age in the TURP group was 65.067 years, with an SD of 4.3243. Comparably, in the Greenlight group, the patient's mean prostate volume was 59.556 gm with an SD of 6.8376, and in the TURP group, it was 51.644 gm years with an SD of 6.6441. With SD of 2.4073, 0.4931, and 3.8076, respectively, the mean operation time, length of hospital stay, and catheterization period with the Greenlight Laser were 72.022, 1.467, and 14.844. The average length of the bipolar TURP procedure, hospital stay, and catheterization were, in order, 54.467, 2.567, and 36.556, with corresponding SD of 6.2943, 0.8765, and 6.6829. Conclusion: The current study concluded that the greenlight laser is a more secure and practical substitute for bipolar TURP. However, large randomised studies are needed to prove that greenlight laser is superior
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    Effect of Aspartame on Hemoglobin in Sickle Cell Anemia
    (Society for Scientific Research, 2024-05) Behera, TK; Behera, JR; Mishra, A; Madhual, S
    Background: Sickle cell disease (SCD) is a monogenic disorder characterized by aberrant hemoglobin S (Hb S) due to an A-to-T mutation in the ?-globin gene. This leads to erythrocytes deforming or sickling, causing sickle cell crises, growth retardation, increased infection susceptibility, chronic hemolysis, multi-system organ damage, disability, and death. Anemia in SCD patients is primarily due to reduced red cell lifespan and hypersplenism in infants. Methods: Patients from the VIMSAR Burla general medicine ward OPD/IPD were randomly assigned to a control group and a study group. Clinical examinations and histories were recorded, including hospital stay frequency, volatile organic compounds, blood transfusion history, and medication use. Patients on hydroxyurea continued their treatment. Conventional blood investigations (CBC, random blood sugar, liver function tests, serum urea, creatinine levels, and urine analysis) were conducted. Results: The study showed that SCD patients in the study group taking 4 mg/day of aspartame had a significant increase in mean hemoglobin percentage starting from the first month and continuing until the third month, compared to the control group. The most substantial therapeutic benefit was observed in the third month. Conclusion: Currently, hydroxyurea is the only FDA-approved effective treatment for SCD, but it it has several side effects. Aspartame, a safer over-the-counter medication, demonstrated greater efficacy than hydroxyurea in raising Hb% and reducing VOC, hospitalisations, and blood transfusions without adverse effects over a six-month trial. Aspartame is suggested as a potential first-line treatment for SCD, warranting a large-scale double-blind randomised controlled study to confirm its therapeutic benefits.
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    Health and Immunization Status of Adolescent School Children in Southern Odisha
    (Society for Scientific Research, 2024-01) Barik, RR; Seth, S; Hari, ST; Behera, JR
    Background: There are major changes in a person's appearance, mental state, and behavior during adolescence, which is an important developmental stage between childhood and adulthood. 20.9% of India's population is under the age of 18, and they face several threats to their health, including early marriage, poor nutrition, and insufficient vaccines. There may be benefits to urbanisation, but there are also health disparities that show how important it is to deal with teen health largely. The objective of the study is to evaluate the health and immunisation conditions of teenage students in Southern Odisha. Methods: When people were interviewed in person, a pre-made questionnaire was used to collect information about their demographics and vaccination history. Height, weight, and BMI were measured by a paediatric resident using standardised equipment and analysed using IAP growth charts. Using a digital sphygmomanometer, blood pressure was logged, and pallor was evaluated by examining the person. The data was analysed using SPSS, and correlations were found using chi-square tests. Results: The study chose 349 students aged between 11–15 from public and private schools in Berhampur who went to the paediatric emergency department from 2019–2021. There were primarily men (66.2%) among the 14-year-olds. 59.3% went to public schools. There were 63.90% fully vaccinated and 36.10% partially vaccinated. The height distribution was 7.2% stunted 1.1% above 97%, and 91.7% normal. Conclusion: The COVID-19 pandemic has exacerbated preexisting conditions, such as obesity and hypertension, which pose serious health risks to India's youth. Increased awareness and immunisation effortsimprove adolescent health.