Browsing by Author "Alcantara, A"
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Item Chloroquine resistant Plasmodium falciparum: effect of rabbit serum and incubation time on the in vitro (microtechnique) prediction of in vivo resistance.(1983-06-01) Smrkovski, L L; Alcantara, A; Buck, R L; Sy, N E; Rodriguez, C S; Macalagay, P S; Uylangco, C BA study of chloroquine resistance of 54 isolates of Plasmodium falciparum is reported. Sixty-four percent of the isolates tested produced schizonts in vitro (micro-technique), whereas the remaining 36 percent did not. The accuracy of the in vitro test to predict in vivo resistance was increased when the primary parasite isolates were cultured in the presence of rabbit serum and when the cultures were allowed to incubate for more than 48 hours. Thirteen isolates of P. falciparum that showed in vitro resistance were confirmed in vivo resistant. Eleven of these cases were identified as R-I and two as R-II. Only one case of in vivo resistance (R-II) was observed among the 19 isolates that failed to produce schizonts in vitro.Item Cryptosporidiosis in Philippine children.(1985-06-01) Cross, J H; Alcantara, A; Alquiza, L; Zaraspe, G; Ranoa, CCryptosporidiosis, a newly recognized parasitosis of humans is being identified with increased frequency in immunocompromised and more recently in immunocompetent persons with gastroenteritis and or diarrhea. It has been found in the Philippines for the first time in children seen at the San Lazaro Hospital in Manila. A total of 735 stool specimens from adults and children with diarrhea were examined by the Ziehl-Neelson and Kinyoun acid-fast methods and 2.9% of the children 6 to 20 months of age were found passing Cryptosporidium oocysts. This parasitic infection should be considered in the differential diagnosis of cases of diarrhea in both immunodeficient and immunocompetent persons.