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    Catheter associated fungal urinary tract infection.
    (2004-04-28) Suwitra, Ketut; ,
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    The correlation between thrombopoietin and platelet count in adult dengue viral infection patients.
    (2004-04-28) Matondang, Asnath Vera; Widodo, Djoko; Zulkarnain, Iskandar; Rengganis, Iris; Trihandini, Indang; Inada, Katsuya; Endo, Shigeatsu; ,
    AIM: To investigate alteration in humoral regulation during the course of dengue viral infection. METHODS: A prospective analytic study had been conducted involving 40 subjects with dengue viral infection. Subjects were recruited according to consecutive non-probability sampling. Subjects were categorized according to days of illness, platelet counts and serum thrombopoietin (TPO) levels. The plasma TPO levels examinations were done once daily until the platelet counts reached more than 100,000/mm(3). RESULTS: Statistical analysis showed the mean serum TPO levels were increased during thrombocytopenia phase of the disease, and differ significantly from the convalescent phase (mean value 428 pg/ml vs 220.1 pg/ml, p= 0.00). There was also a statistically significant inverse correlation between serum TPO levels and platelet counts (p= 0.00). CONCLUSION: TPO levels were significantly increased in adult patients with dengue infection in which platelets in circulation were markedly reduced, and the TPO levels were inversely related to the platelet counts.
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    Epstein-barr nuclear antigen-1 (EBNA-1) in diffuse large B-cell lymphoma and its relationship to the bcl-2 protein.
    (2006-04-27) Purwanto, Ibnu; Kurnianda, Johan; Hutajulu, Susanna Hilda; Widayati, Kartika; Rizki, Mohammad; ,
    AIM: To determine EBNA-1 expression in the tissue of patients with diffuse large B-cell lymphoma and its relationship to bcl-2 expression. METHODS: Paraffin-embedded tissue from 24 cases of diffuse large B-cell lymphoma were stained immunohisto chemically with monoclonal antibody anti-EBNA-1 and anti-bcl-2 using Streptavidin Biotin Complex method. The bcl-2 expression was measured as negative (no staining), positive 1 (weak staining), and positive 2 (moderate to strong staining). The relationship between the immunohisto chemistry results was examined. RESULTS: From the 24 samples, 12 (50%) were EBNA-1 positive and 14 (58.3%) showed expression of bcl-2. Eleven of the 14 samples (90%) showed expression of bcl-2 were EBNA-1 positive, while only 3 of these samples (10%) were EBNA-1 negative. The relationship between bcl-2 expression and EBNA-1 was statistically significant (Chi square-uncorrected 11.2571, p= 0.0036). CONCLUSION: Our results showed that 50% of diffuse large B-cell lymphoma were EBNA-1 positive. Furthermore, EBNA-1 seemed to be correlated with bcl-2 expression.
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    Liver tuberculosis as an etiology in Fever of unknown origin.
    (2005-04-01) Firmansyah, Irman; Jong, Joko B; Nainggolan, Leo; ,
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    Postural shortening due to primary hyperparathyroidism caused by parathyroid adenoma.
    (2006-04-27) Imelda, Fitri; Bandar, Ivo Novita Sah; Setiyohadi, Bambang; Suwondo, Pradana; Nasar, I Made; ,
    Osteoporosis can be primary or secondary. Secondary osteoporosis is the result of an underlying disease such as an endocrine abnormality, and an example of such is primary hyperparathyroidism. The most common cause of primary hyperparathyroidism is parathyroid gland adenoma. The diagnosis of primary hyperparathyroidism is based on the following biochemical examinations: parathyroid hormone, serum calcium, creatinine clearance, 24 hour urinary calcium, and another examination such as parathyroid gland scan. This is a rare case of an adult man who presented with a chief complaint of decreasing body height, back pain, difficulty in taking deep breaths and difficulty in his activities. The patient was diagnosed with primary hyperparathyroidism caused by parathyroid gland adenoma. His complaint was reduced after parathyroidectomy. His new complaint was that his tooth can be pulled out easily. We found high levels of parathyroid hormone and low levels of serum calcium caused by secondary hyperparathyroidism.
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    The role of lipid profile as a risk factor indicator for ischemic stroke at Cipto Mangunkusumo Hospital, Jakarta.
    (2006-01-16) Immanuel, Suzanna; Giantini, Astuti; Dharma, Rahajuningsih S; ,
    AIM: to determine the role of low HDL-cholesterol, and high total cholesterol, LDL-Cholesterol and triglyceride as risk factors for ischemic stroke at Dr. Cipto Mangunkusumo Hospital. METHOD: a study was conducted on 76 patients with an age range of 40-70 years. Subjects consisted of 38 post ischemic stroke patients and 38 control subjects with a diagnosis other than stroke. The study sample consisted of serum for lipid profile assessment. Total cholesterol and triglyceride were assessed using enzymatic method, while HDL-cholesterol and LDL-cholesterol using direct homogenous enzymatic method. Statistical analysis was performed using chi-square and multivariate analysis using logistic regression. RESULTS: low HDL-cholesterol was found in ischemic stroke patients and demonstrated a significant difference compared to control subjects (p<0.05). The results of total cholesterol, triglyceride, LDL-cholesterol did not demonstrate a significant difference. The odds ratio (3.09; CI 95%: 1.04; 8.73) demonstrates that low HDL-cholesterol is a risk factor for ischemic stroke. CONCLUSION: a low HDL-cholesterol level is a risk factor for ischemic stroke, with an odds ratio of 3.09, while total cholesterol, triglyceride and high LDL-cholesterol levels were not risk factors for ischemic stroke.
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    Standard of Competence for Internists.
    (2008-04-06) ,
    The ratification of law No. 29 regarding medical practices required the college to compile the standard of education and standard of competence for specialists.Recently, the College of Internal Medicine have compile the standard of competence for internal medicine specialists/internists, which will be the reference for all Educational Institution in compiling the Education Curriculum for Internal Medicine.The standard of competence for Internal Medicine Specialists/Internists is the minimum standard of competence that must be fulfilled by an internists. Therefore, with its presence, it is expected that participants of Program for Education and Professional Training of Internal Medicine Specialist/Internists who have already completed his/her education and training will have the equal quality of competence.Competence is a group of complex behavior, based on the components of knowledge, skill, and attitude that becomes the ability of a person in upholding his/her duty. In the Standard of Competence for Internal Medicine/Internists book, it is expected that an internist will acquire several competence, including integrated competence and clinical competence, in which clinical competence is further divided in to clinical competence of organ and system, special population, and special condition.