Current trends and advances of Quorum sensing inhibitors and their biotechnological applications

Simple item page
dc.contributor.authorShamshad, Sameren_US
dc.contributor.authorRajagopal, Senthilkumaren_US
dc.date.accessioned2023-08-09T06:03:09Z
dc.date.available2023-08-09T06:03:09Z
dc.date.issued2023-04
dc.description.abstractSerious setbacks were witnessed in shrimp farming, the food industry, and the ship industry during the past three decades primarily due to bacterial pathogens that coordinate by quorum sensing (QS). The influence of bacterial pathogens utilizing QS. The impact of QS cell communication on public health is extremely disastrous in terms of spread, spectrum, apart from their economic impact. The overuse of antibiotics has increased drastically to battle bacterial infections, including tons of antibiotics are distributed in the biosphere. Due to the indiscriminate use of antibiotics, multiple antibiotic-resistant strains have emerged, as the antibiotic resistance genes are being transferred to bacteria of terrestrial animals, humans, and pathogens. The increased public awareness of the negative drawbacks caused by over-exposure to antibiotics, also the emergence of multiple antibiotic resistant pathogenic stains led to the search for alternatives and unique solutions. One such unconventional, promising method is the interruption of bacterial cell to cell communication, which is currently termed QS inhibition. Now-a-days, QS inhibition is the potential objective for antimicrobial chemotherapy. This review summarizes the regulatory factors that attenuate the QS activities of deadly pathogens and discusses their distinctive characteristics. Improving awareness of the natural roles of regulatory elements might be useful in unveiling inhibitor applications to understand how QS is inhibited in pathogenic bacteria by different QS inhibitors.en_US
dc.identifier.affiliationsICAR-National Institute of Veterinary Epidemiology and Disease Informatics, Bengaluru-560 064, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of Biotechnology, School of Applied Sciences, REVA University, Bengaluru-560 064, Karnataka, Indiaen_US
dc.identifier.citationShamshad Samer, Rajagopal Senthilkumar. Current trends and advances of Quorum sensing inhibitors and their biotechnological applications. Indian Journal of Biochemistry & Biophysics. 2023 Apr; 60(4): 255-280en_US
dc.identifier.issn0019-5189
dc.identifier.issn0975-1009
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/221638
dc.languageenen_US
dc.publisherCSIR-NIScPRen_US
dc.relation.issuenumber4en_US
dc.relation.volume60en_US
dc.source.urihttps://doi.org/10.56042/ijbb.v60i4.65104en_US
dc.subjectApplicationsen_US
dc.subjectCell communicationen_US
dc.subjectPathogenen_US
dc.subjectQS inhibitorsen_US
dc.subjectQSen_US
dc.titleCurrent trends and advances of Quorum sensing inhibitors and their biotechnological applicationsen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
IJBB2023v60n4p255.pdf
Size:
4.64 MB
Format:
Adobe Portable Document Format
Download
Collections
Indian Journal of Biochemistry & Biophysics