Respiratory mechanics of infants with bronchopulmonary dysplasia who required long term oxygen therapy

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dc.contributor.authorT. Chaisupmongkollarpen_US
dc.contributor.authorA. Preutthipanen_US
dc.contributor.authorP. Nannarumitreen_US
dc.contributor.authorU. Udomsubpayakulen_US
dc.date.accessioned2011-02-22T08:55:58Z
dc.date.available2011-02-22T08:55:58Z
dc.date.created2010-04-09en_US
dc.date.issued2010-04-09en_US
dc.description.abstractRespiratory mechanics (RM) were prospectively and longitudinally studied in a cohort of 23 infants with bronchopulmonary dysplasia (BPD).\  The aim of this study was to compare pulmonary function in BPD infants who required supplemental oxygen for more than 2 months (the study group, n=15) and in age-matched BPD infants who required supplemental oxygen at 2 months or less (the control group, n=8). Serial pulmonary functions were measured, using a computerized infant pulmonary function device (model 2600; SensorMedics; Yorba Linda, CA, USA), at 6, 12, 18, and 24 months of corrected age. Both groups did not differ for sex, birth weight, gestational age, duration of mechanical ventilation, history of patent ductus arteriosus or respiratory distress syndrome. At 6 months of age, compliance of the respiratory system (Crs) in the study group was significantly lower than the control group (6.8\±2.9 vs. 11.7\±3.6 ml/cm H₂O, p \< 0.05) and at 6, 12, and 18 months of age. Tidal volume in the study group was significantly lower than the control group (43.8\±11.9 vs. 62.4\±14.9 ml; 62.1\±11.8 vs. 79.7\±15.9 ml; 79.9\±14.2 vs. 96.5\±19.1 ml; p \< 0.05).\  Other pulmonary function including functional residual capacity and total respiratory system resistance (Rrs) did not differ between the two groups. We conclude that the pulmonary function status of BPD infants who required supplemental oxygen for more than 2 months need longer time period for recovering from lung injury than the control group.en_US
dc.identifier.citationThai Journal of Tuberculosis Chest Diseases and Critical Care; Vol.29 No.4 October-December 2008; 309-317en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/132658
dc.language.isoen_USen_US
dc.publisherThai Journal of Tuberculosis Chest Diseases and Critical Careen_US
dc.rightsThai Journal of Tuberculosis Chest Diseases and Critical Careen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/TJTCD/issue/archiveen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/TJTCD/article/view/3110en_US
dc.titleRespiratory mechanics of infants with bronchopulmonary dysplasia who required long term oxygen therapyen_US
dc.typeOriginal Articleen_US
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