Analysis of codon usage: positional preference in various organisms.

No Thumbnail Available
Date
1995-06-01
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The degree of preference of the four nucleotides C, G, A and U in the three positions I, II and III of the codons of 15137 genes of various individual organisms is examined using the nucleotide sequence data obtained from the GenBank Genetic Sequence Data Bank (Release 65.0, Sep., 1990). It is found that G, A and C, are preferred maximally in the three positions respectively. Similarly, U, G and A are preferred minimally in these positions. The analysis shows a correlation in the positional base preference which discriminates against codons with the same base in all three positions or in the adjacent positions.
Description
Keywords
Citation
Seetharaman J, Srinivasan R. Analysis of codon usage: positional preference in various organisms. Indian Journal of Biochemistry & Biophysics. 1995 Jun; 32(3): 156-60