Computer simulation of the kinetics of the sodium pump.
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1990-06-01
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Abstract
A simple kinetic model for the membrane-bound enzyme, 'Na+, K(+)-ATPase', is presented. An equation for the efflux of Na+ and influx of K+ is derived. This also explains multiple ligand binding of homospecies of these cations and competition between heterospecies of these cations. The equation is computed by a small BASIC program and its validity is sought by comparing the results with a few experimental data.
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Majumdar MP, Mitra CK. Computer simulation of the kinetics of the sodium pump. Indian Journal of Biochemistry & Biophysics. 1990 Jun; 27(3): 151-4