Correlation of Serum and Urine Sialic Acid Levels with Lipid Profile and Anthropometric Indices in Type 2 Diabetes Mellitus and Diabetic Nephropathy
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Date
2018-10
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Science Domain International
Abstract
Introduction:Sialic acid is a component of vascular cell membranes; the elevated levels indicate excessive vascular damage leading to diabetic complications. Therefore sialicacid can be considered to be newly established potential risk factor for the development of diabetic nephropathy. Aims:To study the correlation between sialic acid levels with lipid profile and anthropometric variables in type 2 diabetes mellitus and type 2 diabetics with nephropathy. Study Design:Case control study Place and duration of study: study was conducted at department of biochemistry and department of medicine at aj institute of medical sciences, mangalore for a period of 2 years.Methodology:Study population included 75 subjects in the age group of 40-70 years out of whom 25 subjects were type 2 diabetics (newly diagnosed or known diabetics on treatment without any complications), 25 subjects were type 2 diabetics with nephropathyand 25 were age andsex matched normal controls. Serum and urine sialic acid, lipid profile and anthropometric variables were measured in study subjects
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Keywords
Diabetes melitus, diabetic nephropathy, ialic acid, body mass index, waist hip ratio.
Citation
K. Prajna, Rai Srinidhi, Rai Tirthal . Correlation of Serum and Urine Sialic Acid Levels with Lipid Profile and Anthropometric Indices in Type 2 Diabetes Mellitus and Diabetic Nephropathy . International Journal of Biochemistry Research & Review. 2018 Oct; 23(3): 1-6