Genetic diversity of 15 autosomal short tandem repeats loci using the AmpFLSTR ® Identifiler™ kit in a Bhil Tribe Population from Gujarat state, India.
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Date
2014-04
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Abstract
MATERIALS AND METHODS: The genetic diversity and
forensic parameters based on 15 autosomal short tandem
repeats (STR) loci; D8S1179,D21S11, D7S820, CSF1PO,
D3S1358, TH01, D13S317,D16S539, D2S1338, D19S433,
vWA, TPOX, D18S51,D5S818, and FGA in AmpFLSTR®
Identifiler™ kit from Applied Biosystems, Foster City, CA,
USA were evaluated in saliva samples of 297 unrelated
individuals from the Bhil Tribe population of Gujarat state,
India to study genetic diversities and relatedness of this
population with other national and international populations.
RESUITS: Statistical analysis of the data revealed all loci
were within Hardy-Weinberg Equilibrium expectations
with the exception of the locus vWA (0.019) and locus
D18S51 (0.016). The neighbour joining phylogeny tree and
Principal Co-ordinate Analysis plot constructed based on
Fst distances from autosomal STRs allele frequencies of
the present study and other national as well as international
populations show clustering of all the South Asian
populations in one branch of the tree, while Middle Eastern
and African populations cluster in a separate branch.
CONCLUSION: Our findings reveal strong genetic affinities
seen between the Indo-European (IE) speaking Bhil Tribe
of Gujarat and Dravidian groups of South India.
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Keywords
Allelic frequencies, Bhil Tribe, genetic distance, genetic diversity, short tandem repeats
Citation
Chaudhari Ramesh R, Dahiya M S. Genetic diversity of 15 autosomal short tandem repeats loci using the AmpFLSTR ® Identifiler™ kit in a Bhil Tribe Population from Gujarat state, India. Indian Journal of Human Genetics. 2014 Apr-Jun ; 20 (2): 148-152.