Genetic diversity of 15 autosomal short tandem repeats loci using the AmpFLSTR ® Identifiler™ kit in a Bhil Tribe Population from Gujarat state, India.

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dc.contributor.authorChaudhari, Ramesh R
dc.contributor.authorDahiya, M S
dc.date.accessioned2015-03-09T08:46:44Z
dc.date.available2015-03-09T08:46:44Z
dc.date.issued2014-04
dc.description.abstractMATERIALS AND METHODS: The genetic diversity and forensic parameters based on 15 autosomal short tandem repeats (STR) loci; D8S1179,D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317,D16S539, D2S1338, D19S433, vWA, TPOX, D18S51,D5S818, and FGA in AmpFLSTR® Identifiler™ kit from Applied Biosystems, Foster City, CA, USA were evaluated in saliva samples of 297 unrelated individuals from the Bhil Tribe population of Gujarat state, India to study genetic diversities and relatedness of this population with other national and international populations. RESUITS: Statistical analysis of the data revealed all loci were within Hardy-Weinberg Equilibrium expectations with the exception of the locus vWA (0.019) and locus D18S51 (0.016). The neighbour joining phylogeny tree and Principal Co-ordinate Analysis plot constructed based on Fst distances from autosomal STRs allele frequencies of the present study and other national as well as international populations show clustering of all the South Asian populations in one branch of the tree, while Middle Eastern and African populations cluster in a separate branch. CONCLUSION: Our findings reveal strong genetic affinities seen between the Indo-European (IE) speaking Bhil Tribe of Gujarat and Dravidian groups of South India.en_US
dc.identifier.citationChaudhari Ramesh R, Dahiya M S. Genetic diversity of 15 autosomal short tandem repeats loci using the AmpFLSTR ® Identifiler™ kit in a Bhil Tribe Population from Gujarat state, India. Indian Journal of Human Genetics. 2014 Apr-Jun ; 20 (2): 148-152.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/156651
dc.language.isoenen_US
dc.source.urihttps://www.ijhg.com/article.asp?issn=0971-6866;year=2014;volume=20;issue=2;spage=148;epage=152;aulast=Chaudharien_US
dc.subjectAllelic frequenciesen_US
dc.subjectBhil Tribeen_US
dc.subjectgenetic distanceen_US
dc.subjectgenetic diversityen_US
dc.subjectshort tandem repeatsen_US
dc.subject.meshDNA Fingerprinting --methods
dc.subject.meshGene Frequency
dc.subject.meshGenetic Loci --genetics
dc.subject.meshGenetic Variation --genetics
dc.subject.meshGenetics, Population --methods
dc.subject.meshGenotyping Techniques --methods
dc.subject.meshHumans
dc.subject.meshIndia
dc.subject.meshMicrosatellite Repeats --genetics
dc.subject.meshPopulation Groups --genetics
dc.titleGenetic diversity of 15 autosomal short tandem repeats loci using the AmpFLSTR ® Identifiler™ kit in a Bhil Tribe Population from Gujarat state, India.en_US
dc.typeArticleen_US
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