International Journal of Ayurveda and Pharma Research

Permanent URI for this collection

https://imsear.searo.who.int/handle/123456789/149872

Editor in Chief: Dr. B. Srinivasulu

ISSN: ISSN : 2322-0910 (Online) 2322-0902 (Print)

Frequency: 6 issues a year

Language: English

Online peer reviewed journal

Web site: https://ijapr.in/

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Now showing 1 - 20 of 632

Ayurvedic Emphasis in Duchenne Muscular Dystrophy: A Case Study
(Mahadev Publications, 2023-02) Khose, Pooja Sopan; Kale, Anil B.; Swami, T. Y.; Bodu, Deepali Suresh
Duchenne muscular dystrophy is one of the most common dystrophinopathies known. It is the most common hereditary neuromuscular disorder and is inherited in an X-linked recessive manner. Incidence is 1:3500 live male infants, characterised by progressive weakness of a selective group of muscles without involvement of nervous system. Age of onset being 3-10 years, many children unable to walk before 18 months of age. The patient usually dies by 18-20 years of age. 80% carries have high CPK values with female being the one. Dystrophin gene is the largest human gene with 79 exons, codes for protein dystrophin required for stabilisation of protein complex at sarcolemma, the abnormal DMD gene is on X chromosome at Xp21 locus. Dystrophin deficiency thus, leads to destruction of muscle fibres and progressive muscular weakness. Corticosteroids are the only medications that have shown to alter the course of DMD but have side effects like weight gain, decreased appetite, increase changes of cataract and osteoporosis. The present study is about management 8 years old male child with B/L lower limb weakness and calf muscle hypertrophy.etc, so according to Ayurvedic management with Panchkarma procedures and internal medicines given the case was managed. Successful improvement in CPK values along with the signs and symptoms was observed. As per Ayurvedic Siddhant and Samprapti application considering Adibalapravrittavyadhi and the Beejabhaga avayava dushti the management done. There is no treatment in any system of medicine and prognosis being unpreventable, Ayurveda instills a regenerative mechanism in neuromuscular disorders with special concern of Panchkarma, Rasayanas, Rasa aushadhi, etc. By this the deterioration can effectively be prolonged and quality of life improved.
A Single Centre Open Label Non-Randomized Phase-IV Post Marketing Surveillance Study to Evaluate the Efficacy and Safety of Roop Mantra Ayurvedic Medicinal Cream
(Mahadev Publications, 2023-02) Kimtata, Vijay; Gupta, Vishu; Singh, Lakhbir; Ahmed, Hasan Ali Ahmed Ali; Yogeesh, H R
Objectives: The objective of the study was to evaluate the efficacy and safety of a polyherbal Roop Mantra Ayurvedic Medicinal Cream in subjects with acne, facial scars, pimples, blemishes, dull and dry skin. Methods: This was a 60-day, single-centre, open-labelled, non-randomized phase-IV surveillance study with 120 subjects. Subjects were selected based on the study's inclusion criteria. The study included three scheduled clinical visits on days 0 (screening and baseline visit), 30 (follow-up visit), and 60 (final visit). Following an evaluation of baseline data, all subjects were given Roop Mantra Ayurvedic Medicinal Cream for 60 days. The primary outcome of the study was to assess the efficacy of Roop Mantra Ayurvedic Medicinal Cream based on changes in parameters such as skin texture, skin health, global acne assessment parameters and an investigator assessment scale. The secondary outcome of the study was the determination of local intolerance and adverse effects to Roop Mantra Ayurvedic Medicinal Cream . Results: The study findings revealed that the use of Roop Mantra Ayurvedic Medicinal Cream for 60 days improved skin texture and appearance while significantly reducing acne, pimples, blemishes, and skin dryness. Roop Mantra Ayurvedic Medicinal Cream was likewise dermatologically well tolerated and did not cause any adverse effects during the study period. Conclusion: Roop Mantra Ayurvedic Medicinal Cream showed highly satisfactory results in terms of skin texture, skin appearance and general acne parameters without having any adverse effects on the skin. Given the positive outcomes, Roop Mantra Ayurvedic Medicinal Cream is clinically effective and safe alternative for treating various skin problems.
Role of Sthanik Chikitsa in Shweta Pradara Associated with Madhumeha (DM Type- II): A Case Study
(Mahadev Publications, 2023-02) Akshita; Kapil, Soni
Shweta Pradara or excessive vaginal discharge is one of the commonest complaints among women of reproductive age group. An increase in the normal vaginal secretion develops physiologically at puberty, at ovulation, premenstrual phase and during pregnancy. Excessive discharge causes irritation and itching in the genetalia. Ayurveda explained this condition as Shweta Pradara. Shweta Pradara is a symptom which is present in most of the diseases or present as a complication. Shweta Pradara is not a disease it produces as a symptom, hence etiopathogenesis of principal disease and Shweta Pradara would be same. It is a Kaphaja disorder at the place of Apana Vayu. A 47 years old female patient suffering from intermittent Yonigata Shwet Strava since two years with aggravation of symptoms from one week presented to Prasuti Tantra Evam Stree Roga OPD. Yonigat Shwet Strava was associated with Yoni Kandu, Katishool, Yoni Daha. On enquiry, it was found that she was the known case of Type II Diabetes Mellitus since 10 years. She was taking medication for the same but her blood sugar levels were uncontrolled in spite of taking medication as per her recent investigations. In this case Shwet Pradar was the Updrava of Madhumeh, thus line of management was planned to control her sugar level by supplementing Ayurvedic drugs along with allopathic medicine for DM II (Madhumeh) and treated her with Yoniprakshalan with Triphala Kwath followed by Cutis ointment tamponing per vaginum for 14 days. She had followed the schedule of Yoni Prakshalana, oral medicines and Pathya-Apathya properly. It was observed that, symptoms were started to reduce gradually which has been depicted by documentation of investigations and local examination in this case study.
Management of Diabetic Macular Edema Through Ayurveda: A Single Case Study
(Mahadev Publications, 2023-02) Gupta, Garima; Soni, Rajendra Kumar
Diabetic macular edema is one of the leading causes of visual acuity loss in people with diabetes. It produces blurry vision, particularly in the centre of the vision field, floaters and black spots in front of the eyes etc. The treatment recommended by modern science is laser photocoagulation and anti-VEGF injection, which is pricey and does not ensure visual reversal in the patient. In Ayurveda text, diabetic retinopathy and diabetic macular edema are not directly described but etiopathogenesis of eye diseases and Prameha gives an idea of possible correlation between these two diseases. So, DME resembles Timira (Pramehajanya). In Ayurveda, Timira has been explained in detail by our Acharyas. Clinical manifestations of Timira are Vihwal Drishti (blurred vision), Makshika Mashaka Kesha Jaala Pashyati (floaters), Tamasa Darshanam (Scotoma- black spots in front of eyes) and Nasa Akshi Yuktani Vipritani Vikshate (Metamorphopsia or distorted vision) which has similarity with features of DME. Material & Methods: In the present study, a female patient aged 51 years, visited the Shalakya Tantra OPD of National Institute of Ayurveda, Jaipur, with complaining of Blurriness of vision since 6 months and uncontrolled blood sugar level. Result: Blood sugar level was controlled and saw reduction in subjective and objective parameters. Discussion: Following an Ayurvedic drugs and routine will assist to slow the advancement of the condition, prevent further diabetes complications, and improve quality of life.
Medico-Ethon-Botanical Study of Indigenous and Migrated Medicinal Plants Diversity at Kothi Village in Kangra District of Himachal Pradesh in India: A Cross-Sectional Survey
(Mahadev Publications, 2023-02) Pandit, Ram Deo; Rana, Shefali
Ayurveda and medicinal plants of folklore are the primary sources of health care in rural areas of India. Medicinal plants are the basis of Ayurveda drugs. Kothi village at an elevation of around 1,100m from the sea level is a hamlet in Kangra District of Himachal Pradesh and it has a good diversity of medicinal plants. The medicinal plants' diversity in this village is not studied to date. This cross-sectional survey study (observational study of descriptive and analytical type) was conducted to discover the diversity of medicinal plants in the Kothi village. The medicinal plant diversity at RGGPGAC&H territory was the sample chosen for this study. The total diversity of medicinal plants in the Kothi village was considered as the population of the study. Questionnaire based interviews and discussions with local villagers and sellers were used as a method for medicinal plants sample collection from the sample area. The sample medicinal plants were then verified by the faculty of PGDD at RGGPGAC&H. After verification, samples were cross-verified with authoritative publications by the government of Himachal Pradesh and India. A total of 151 different indigenous cum migrated medicinal plant diversity belonging to 69 families is found occurring in the Kothi village.
Ayurvedic Management of Primary Infertility Associated with PCOS - A Case Report
(Mahadev Publications, 2023-03) Vimal, Vijila; Laxmipriya, Dei
Poly cystic ovarian syndrome is a condition characterised by a wide range of signs and symptoms including menstrual irregularities, obesity, acne, hirsutism and is causing adverse effects on metabolic and endocrinal system. Exact etiology and pathophysiology is still unclear but it’s having a strong familial predisposition. This is a case report on an anovulatory infertility caused by PCOS. A 27-year-old female patient presented to the Streeroga OPD at ITRA On December 29, 2020, complaining of infertility, irregular and delayed menstruation, and weight gain over the past three years. She has been taking allopathic medicine for the same for the last two years. During her initial opd visit, she received a thorough medical history as well as all relevant clinical, physical, and laboratory tests. Bulky ovaries with polycystic morphology were discovered on sonography. Anovulatory factor infertility owing to PCOS was determined based on clinical symptoms and sonography. Pathadi choorna and Arogyavardhini rasa were chosen as medications and Samana oushadha was chosen as the line of management. The patient was counselled on lifestyle changes, the need of exercise, and correction of food habits. Patient was under medication for a period of 5 months. Patient got conceived after that and on 8th February 2022 she gave birth to a healthy male baby per vaginally with a baby weight of 3.2 kg.
Varmam Therapy for Common Shoulder Joint Pathological Conditions- A Review
(Mahadev Publications, 2023-03) S, Kavitha; S, Magudapathi; M, Suguna; V, Manjula; G, Dhinesh Raman
Varmam- a discrete medical science and a great contribution of Siddhars to Tamil Nadu. It encompases Varma martial arts, Varma therapy, internal and external medicines. Varma therapy and medicines effectively treat neuro musculoskeletal conditions which is admirable. Shoulder pain is most common orthopaedic condition. It is the third common cause of musculoskeletal consultations in primary care. Approximately 1% of adult develops new shoulder pain annually. Common pathological conditions of shoulder like rotator cuff disorders and adhesive capsulitis etc exhibits similar clinical features like pain and stiffness of shoulder joint and restricted movements. Varma therapy rearranges and regulates the “Vaasi” and consequently helps to maintain the equilibrium of trihumours (Vatham, Pitham, Kapham). This review article explicates the Varma points for the treatment of shoulder pathological conditions, the exact anatomical location of Varma points and the appropriate method of its manipulation, certainly a key to further research articles.
Parallel Study of Medodhara Kala and Abdominal Adipose Tissue with Special Reference to Sthoulya (Obesity)
(Mahadev Publications, 2023-03) Deshpande, Pradnya R; Pande, Prasad P; Swami, Shital S
Obesity which is neuroendocrine disorder seems to be common predisposing factor for almost all non-communicable diseases. This neuroendocrine disturbance causes multiple systemic disorders and finally Ayurhasa (reduction in longevity of life) by various means. Ayurveda mentioned eight pathophysiological conditions considered as Nindya (worse conditions). Atisthool (excessive weight) is one of these conditions due to improper Aahara (dietary habits), Vihar (sedentary life style) and changed sleep pattern. Apachita meda (improperly metabolized fat) deposited in Udara (abdomen). Medodharakala according to Ayurveda and abdominal linings bear several similar characteristics related to fat and Medodhatu deposition. Deterioration of functioning of Medodhara kala leads to deposition of Apachita meda leading to Sthoulya. In obesity, abdominal wall, space between organs stores much amount of adipose tissue (site of Meda deposition). So this article reveals with parallel study of Medodhara kala and abdominal adipose tissue to find out similarity.
Ayurvedic Management of Acute Dissociative Reactions to Stressful Life Events - A Case Study
(Mahadev Publications, 2023-03) K, Ragitha; K, Satheesh
Mental diseases known as dissociative disorders are characterised by a sense of discontinuity and separation from one's thoughts, memories, environment, activities, and identity. People with dissociative disorders unintentionally and unhealthily flee reality, which makes it difficult for them to carry on with daily activities. Dissociative identity disorder (DID, sometimes known as multiple personality disorder), fugue, "psychogenic" or "functional" amnesia, and depersonalization disorder are examples of dissociative disorders. Other specified dissociative disorder is subcategory of dissociative disorders that describes presentations in which symptoms are typical of a dissociative disorder but do not fully match the diagnostic criteria for any of the illnesses in the diagnostic class of dissociative disorders. In Ayurveda this condition can be considered as Unmada. 34 year female patient hailing from Malappuram, Kerala, brought to Manasanthi OPD of VPSV Ayurveda College, Kottakka,l by husband and relatives complains of lack of desire to live, wants to end her life, loss of sleep, difficulty to walk and doing daily activities since 3 days. She was very much concerned about the behavioural issues and wellbeing of her elder son since 12 years. According to the informant, the patient was having increased tension, repeated talking about her elder son, making loud noises and suicidal thoughts. Also, she had an attempt to suicide. She was treated on an IP level with a combination of Ayurvedic internal medications and Panchakarma procedures. The treatment protocol includes Snehapana, Virecana, Nasya, Shirodhara, and Dhoopana. Satvavajaya methods including Yoga also administered. There were considerable relief from symptoms and HAM D score was reduced from 21 to 6.
An Analytical Review on Health Benefits of Prenatal Yoga for Mother and Foetus
(Mahadev Publications, 2023-03) Patni, Kalpana; Sinha, Gaurav
Pregnancy is a physiological condition in which would be mother changes both from inside as well as outside. Yoga in pregnancy can help the women to balance through these physical, mental and emotional challenges. Embracing yoga during pregnancy provides multi dimensional benefits to mother and baby. Yoga calms the mind, revitalizes the energy and prepares the woman physically and mentally for delivery. Various respiratory exercises (Pranayama) and physical postures (Asanas), performed by a pregnant woman under expert supervision, can help in harmonized relaxation and contraction of uterus, increase the strength, flexibility and endurance of muscles needed for childbirth,. They devour low energy and afford greater benefits. Also Yoga-sasanas can minimizes the complication of pregnancy, like pregnancy induced hypertension, intrauterine growth retardation and pre-term delivery. Yoga calms the mind, re-energies and prepares the mother physiologically, mentally and emotionally and for labour. Yoga is also helpful in improving sleep pattern, reduces lower back pain, nausea, headaches and shortness of breath. Simple stretching exercises encourage circulation, help fluid retention, and relieve stress. Yogic exercises can help pregnant women recover faster post-delivery. Different type of postures, mentioned in Ayurvedic and Yogic texts that can be comfortably performed in pregnancy. They consume lower energy and give better benefits. Yoga is useful for a variety of immunological, behavioral and psychosomatic conditions. Various research studies regarding the utility of yoga interventions for pregnancy shows that it is helpful in improving pregnancy and birth outcomes. Numerous clinical studies shows that yoga may produce improvements in stress levels, quality of life, aspects of interpersonal relating, autonomic nervous system functioning, and labour parameters such as comfort, pain, and duration.
A Conceptual Study on Buddhi, Dhee, Dhriti, Smriti, Smritikaaranas and Medha in Comparison to Jean Piaget’s Cognitive Development Factors
(Mahadev Publications, 2023-03) S, Ashigha; Puranik, Prathviraj; Kavya
Building intricate scenarios and sharing these ideas with others, A full-fledged language capacity, as well as reasoning and planning skills are among the many cognitive abilities that distinguish man from other living beings. One of the tools of cognition and perception used to establish the precise qualities of an object according to Ayurveda is Buddhi (intellect). Perception occurs when the Indriyas (cognitive organs) perceives their objects along with Manas (mind), which subsequently analyze and forwards those to Buddhi producing knowledge. Dhee, Dhriti, Smriti are the components of Buddhi which aids for this and Medha is a type of intellect having the power to retain this knowledge. As per modern, cognition is the mental action or process that involves thought experiences, and the senses to acquire knowledge and understanding. The cognitive development is established through schema, assimilation, accommodation and equilibrium according to Jean Piaget’s Cognitive Development Theory. Buddhi, Dhee, Dhriti, Smriti, Smritikaarana, Medha can be correlated to these factors. Although the components of cognitive development theory were articulated for a developing kid, Ayurveda views these concepts as that which may be implied at any stage of life. One has to pass through each of these stages to achieve cognition. Hence, the present conceptual study thus focus on interpreting these Ayurvedic observations on the basis of modern theory of cognitive development and its factors.
A Case Study of Successful Ayurveda Management in the Patient of Migraine (Ardhavabhedaka) and Motion Sickness
(Mahadev Publications, 2023-02) Naram, Smita; Gawali, Komal; Parekh, Hemang
Migraine is a type of Headache characterized by moderate to severe throbbing pain, generally associated with nausea, vomiting and light sensitivity. It can be correlated to Ardhavbhedaka, which according to the Ayurvedic science is caused by simultaneous vitiation of all the three Doshas viz. Vata, Pitta and Kapha. Motion sickness is also a common disorder wherein patient suffers from symptoms like nausea, vomiting, increased salivation, dizziness, upon getting triggered by certain movements. In this case study, a female patient of middle age group (Madhyam Avastha) suffering from long standing migraine and motion sickness since past 15 years (on and off), hampering her day to day activities, was administered with the treatment protocol as per Ayurveda resulting in significant relief to her symptoms. The treatment, planned according to her pulse diagnosis and clinical examination, was based on herbal supplements, Panchakarma (detoxification) in the form of Virechana, home remedies, Marmaa therapy, dietary and lifestyle modifications. The treatment was focused on removing the toxins (Aam) from the body with the help of detox (Virechana). This also resulted in alleviation of the vitiated Vata and Pitta Doshas and restoration of the Jatharagni (digestive fire). The treatment modality has been effective to reduce the episodes significantly.
Evidence Based Study of Surasadi Gana on Respiratory Disorders: A Review
(Mahadev Publications, 2023-03) Choudhary, Kishan Gopal; Rawat, Himanshu; Ojha, Nisha
Introduction: Collection of medicinal herbs having similar effect are collectively known as Gana (group) in Samhita and Vargas (category) in Nighantu. Surasadi Gana is included in 37 of such groups mentioned in Sushruta Samhita, with 21 Herbs completing the group. This article is made in a view to review the importance and utility of few herbs included in Surasadi Gana indicated for the management of respiratory disorders. Material and Methods: The literature regarding the drugs mentioned in the group, collected from different Ayurveda classics. Research papers are compiled from published sources and discussed in light of therapeutic effects. Observation and Result: Maximum of the herbs in this group are having properties as Katu rasa (pungent) and Ushna veerya (hot potency). Such herbs are predominantly advised in Kapha (phlegm humour) dominant diseases, viz. Kasa (cough), Shwasa (asthma), Pratishyaya (common cold), Kushtha (skin disorders), Krimi (worm infestation) and Vrana (wound). Conclusion: The herbs, despite having several Ayurvedic indications, the respiratory tract is the focus of the specific activity.
A Conceptual Recapture of Stanya Kshaya and Role of Stanya-Janan Mahakashaya in its Management
(Mahadev Publications, 2023-03) Goyal, Swati; Verma, Nitin
Breast milk is the prime source of nourishment and immunity of the baby. Stanya Kshaya, which appears to be a fairly simple ailment but is really problematic for children's health, is one of the problems of present era. Lactation insufficiency is 30–40% prevalent in Asian and tropical nations like India. In Ayurveda certain herbs are specifically indicated for increasing breast milk and Acharya Charaka has described Stanya-janana Mahakashaya for it. Few explorations have been conducted regarding above, but no one has covered all aspects comprehensively thus this paper aim to collect and comprehensive review information available regarding concept of Stanya, its Kshaya and role of Stanya-janana Mahakashaya in its management. Methodology: This review is in a narrative format and done from literature and publications relevant to Stanya Kshaya and role of Stanya-janana Mahakashaya. Results: Stanya has been described in detail along with opinion of various Acharyas, Stanya sampata and the reasons for Stanyakshya mentioned then finally role of Stanya-janana Mahakashaya of Acharya Charaka which includes 10 herbs as- Veerana, Shali, Shasthik, Ekshuvalika, Darbha, Kusha, Kaasha, Gundra, Ithkata, Katruna. Drugs in this Kashaya help in increasing quantity of milk. Discussion: Stanya-janana Mahakashaya has active principles which increase quantity of milk, so can be used in Stanya Kshaya and leads to healthy Stanya.
The Role of Rasaja Bhava (Nourishing Factors) in Development of Garbha (Embryo/Foetus)
(Mahadev Publications, 2023-03) Gopal, Uma B; Phatak, Anagha R.; P, SJigisha; S, Dharanesh
Archaic scholars of Ayurveda lay great emphasize on intake of Ahara (food) as best source for nourishment and has a prime role in growth and development of foetus during pregnancy. In order to achieve a healthy progeny, Ayurveda classics have elucidated wholesome regimen to be followed by the parents before and after conception. There are specific procreating factors which help for the growth of embryo known as Matrujadi shad bhava (maternal and other 5 factors). Shadbhava (six factors) consist of Matruja, pitruja, Atmaja, Rasaja, Satmyaja and Satwaja in which Rasaja bhava plays an important role in providing nutrition to the foetus. The concept of Upasneha, Upasweda, Ambu, Apara and Nabhinadi are involved in nourishment of embryo/foetus at different stages of development. Acharya have drawn attention to certain food habits, to be avoided by the pregnant woman to refrain from abnormalities in the offspring. The concept of nutrition in Garbhini (Gravid Women) explained in classics has similarity with contemporary science.
An Ayurvedic Approach in Infertility w.s.r to Tubal Blockage-A Case Report
(Mahadev Publications, 2023-03) Sharma, Chanchal; Mishra, Pragya
Vandhyatva (infertility) is failure to conceive or give birth or experiencing Garbha Strava or Garbha pata (repeated abortion). Disturbed lifestyle, usage of contraceptives, stress, genetic problems, alcohol consumption and smoking addiction increases such cases day by day. Nowadays fallopian tube blockage has become one of the burning issues of female infertility. According to Ayurveda, successful conception depends upon Ritu, Kshetra, Ambu and Beeja. Beejagrahana is unable due to tubal blockage (Sanga Srotodusti of Arthavavaha) leads to failure of conception. Panchakarma plays an important role in treating female infertility and Uttara Basti is one of the best (Panchkarma therapy for the infertility treatment in Ayurveda). It detoxifies the uterine cavity and fallopian tubes, which clear the Srothoavarodha. Uttarbasti along with internal medication helps in Vata Dosha saman and remove the Sanga srotodusti. A diagnosed case of infertility due to bilateral tubal blockage, visited our clinic for treatment of tubal blockage and consequent infertility. Here is the case presentation of successful treatment with Ayurveda medicines and Uttara basti.
A Case Study on Ayurvedic Management in Insulin Resistance in Polycystic Ovarian Disease
(Mahadev Publications, 2023-03) G S, Anju
Polycystic ovarian disease is highly prevalent hormonal and metabolic disorder among reproductive aged women worldwide characterised by hyperandrogenism, chronic anovulation and polycystic ovaries. Insulin resistance is now recognised as a basic underlying pathology of PCOD and found in approximately 50-70% of patients. It is defined as a state in which greater than normal amounts of insulin are required to produce a quantitatively normal response. It is associated with an increased risk of various metabolic disorders including type 2 diabetes mellitus, hypertension, dyslipidaemia and cardiovascular diseases, which indicates that timely therapeutic intervention in PCOS could prevent or at-least delay the onset of type 2 diabetes mellitus and other long-term health risks. Most of the features of PCOD associated with insulin resistance can be found under Santharpanajanya vyadhis with involvement of three Doshas and Dhathus like Rasa, Raktha and Medus. Here is a case report of 18-year-old female who presented with irregular menstruation, rapid weight gain and blackish discoloration of back of neck. Her USG findings shows bilateral polycystic pattern of ovaries. Based on clinical features and laboratory values, treatment principles adopted are Agni deepana, Ama pachana, Vatha-kaphahara and Lekhana. Varanadi kashyam and triphala choorna with takra given internally for 3 months and Udwartana was done externally for 14 days. After 3 months of treatment considerable reduction in weight and improvement in insulin resistance were noticed and her menstrual periods were normal with normal USG findings. The present case signifies the importance of Ayurvedic management in insulin resistance of PCOD to prevent forthcoming complications.
Stability Study of Pashanbhedadi Churna Used in Treatment of Ashmari (Renal Calculi): with Respect to Baseline Microbial Diagnostic Modalities
(Mahadev Publications, 2023-03) Koriya, Hetal; Cholera, Meera; Dudhamal, T.S.
Ashmari (Renal Calculi) is most common disease of urinary system. Ashmari or calculus looks like small gravels/stones hence they are termed as Ashmari. For the treatment of Ashmari Pashanbhedadi Churna was taken as a trial drug. As Pashanbhedadi Churna was trial drug it was necessary to check the stability. Stability of the drug is the time period from the drug production until the time it is intended to be consumed. So, present study was carried out to know the stability of Pashanbhedadi Churna and to check microbial contamination in the Pashanbhedadi Churna at different time interval. Pashanbhedadi Churna was stored in plastic bag. Microbial study of the drug was done at different climatic conditions, humidity and temperature set ups with regular intervals for a period of 11months to analyse mycological and bacteriological findings by wet mount preparation and Gram stain test respectively. Though in different climate, temperature and humidity conditions, at the end of microbial study, Churna has shown absence of microbes for approx.11 months of preparation of drug. So, it is showed that drug is stable in minimum 32°C temperature to maximum 38°C and minimum humidity 23% to maximum 74% humidity. That means stability duration of drug after preparation is approx. 11 months which showed that drug was in a standard condition. Hence it is concluded that stability test of Pashanbhedadi Churna with respect to microbiological findings was negative at room temperature, warm and cold, dry and humid conditions.
Kerala Traditional Ayurvedic Practices in Children for Enhancing Immunity - A Systematic Review
(Mahadev Publications, 2023-03) L, Veena; M S, Anu; Robin, Delvin T; Dileep, Anusree
Kerala is rich in its culture for the traditional Ayurveda practices in children from the time of birth onwards. These traditional practices are mainly immune boosters and also enhance overall nourishment and development in children. Commonly used traditional Ayurveda practices are Uramarunnu Prayoga, Prakara Yoga, Abhyanga, Rasanadi churna lepana, Snana etc. for enhancing immunity and providing overall development to children. Uramarunnu is a baby care practice comprising of a group of drugs administered to the child in the form of paste in breast milk, after 28 days till 2 years of age. Prakara Yogas are immunomodulatory recipes and procedures to be adopted right from the day after delivery. Abhyanga provides nourishment, health, protection, emotional well-being and improves skin tone. All these can be used for enhancing immunity and preventing recurrent infections thereby helps in the maintenance of health and prevention of diseases. This mentions the importance of Kerala traditional Ayurvedic practices in the field of primary child health care. So, the present study aims to compile Kerala’s traditional Ayurvedic practices in children, by reviewing regional textbooks like Arogyakalpadruma, Vaidya Tarakam, Parambarya Balachikitsa etc., and also interviewing Ayurveda pediatrician through telephone.
Evaluation of Antipyretic Activity of Siddha Herbomineral Formulation - Surangusa Parpam
(Mahadev Publications, 2023-03) G, Manikandan; M R, Srinivasan; P, Kayalvizhi; M K, Sangeetha; K, Rajakumar; K, Karpagavalli; I, Nithyamala
The aim of the present study was to assess the antipyretic activity of Siddha herbo-mineral formulation Surangusa Parpam at the dose level of 15mg/kg and 35mg/kg body weight, orally, in brewer yeast induced fever model Wistar rats. Fever was induced by subcutaneous injection of 10ml/kg of 20% w/v aqueous suspension of brewer’s yeast into the nape of the rat's neck. After eighteen hours feverish animals were treated with Surangusa Parpam 15mg/kg and 35mg/kg body weight, orally, and rectal temperatures were evaluated at 0, 1, 2 and 3 hours post-treatment by inserting a well-lubricated bulb of the clinical thermometer. Surangusa Parpam showed a significant decrease in the elevated body temperature of rats that remained sustained throughout the tested time points from 1 to 3 hours in the used model. 35mg/kg body weight dose level showed significant inhibition of elevated body temperature when compared with the standard control. These results indicate that the Antipyretic activity of Surangusa Parpam and in addition to its well-established anti-inflammatory activity possesses significant antihistamine activity that may be beneficial in symptomatic relief when it is used in the therapy of allergic and inflammatory disorders.

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