National Journal of Physiology, Pharmacy and Pharmacology

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https://imsear.searo.who.int/handle/123456789/149612

Editor: Dr. Jay Charan

ISSN: 2320–4672 (Print)

Frequency: 2 issues a year

Language: English

Open Access Peer-reviewed journal

Web site: https://www.njppp.com/

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Now showing 1 - 20 of 695

A study on lipid profile in thyroid dysfunction
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) D, BP; Maliekkal, J; N, G; H, ANV.
Background: Thyroid diseases are among the most common endocrine disorders worldwide. Thyroid hormones play a key role in regulating the synthesis, metabolism, and mobilization of lipids. Levels of circulating lipids may alter in thyroid dysfunction. Aim and Objectives: The aim of the study was to find out the alterations of lipid levels in thyroid dysfunction. Materials and Methods: The study was designed as cross-sectional observational study and analysis of values was done by significant tests difference in means. 20 patients with hypothyroidism, 20 patients with hyperthyroidism, and 20 normal were participated in the study. Levels of total cholesterol, triglycerides, high density lipoprotein cholesterol (HDL-C), very low density lipoprotein cholesterol (VLDL-C), LDL-C, and LDL/HDL ratio were estimated and compared. Results: In patients with hypothyroidism, there was an increase in total cholesterol, LDL-C, and triglyceride levels and decrease in HDL-C levels. In hyperthyroidism, total cholesterol, triglycerides, LDL-C, VLDL-C, and LDL/HDL ratio were found to be significantly decreased. Conclusion: Altered thyroid function can lead to significant changes in the lipid profile. Hypothyroidism is an important risk factor for heart diseases. Hence, routine screening of thyroid hormones may be of considerable help for early intervention and treatment of thyroid dysfunction-related cardiac disease.
Assessment of depression, anxiety, and stress in Type 2 diabetic patients: A case–control study
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) J, S; S, P; Y, D; N, KM.
Background: Diabetes is one of the most common diseases throughout the world that leads to the highest mortality and morbidity. Aim and Objectives: The present study was undertaken to observe depression, anxiety, and stress levels in Type 2 diabetic patients and compare them with healthy controls. Materials and Methods: A total of 30 diabetic patients with Type 2 diabetes and 30 age and gender-matched healthy controls were part of the study after obtaining written informed consent. The assessment of depression, anxiety, and stress was performed using the standard questionnaire DASS 21. Results: There was a significantly higher level of depression scores observed in the cases when compared with the control group. Anxiety scores were significantly higher in diabetic patients when compared with the control group. Stress scores were significantly higher in diabetic individuals when compared with the control group. Conclusion: The levels of depression, anxiety, and stress were significantly higher in the diabetic group compared to the control group. Further detailed studies are recommended in this area to adopt the diagnosis and management of depression, anxiety, and stress levels in diabetic patients.
A cross-sectional study to assess hypothyroid status of pregnant women at 12–16 weeks of gestation
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Kulkarni, RR; Marulasiddappa, PK; Patil, P; Goudar, SS.
Background: Physiological changes occur during pregnancy. These changes include metabolic, hematologic, cardiovascular, renal, and respiratory changes. In some cases, these changes may alter and lead to complications which result in adverse pregnancy outcomes. In India, hypothyroidism in pregnancy has a prevalence of 4.8–11%. Aims and Objectives: The aim of this study was to estimate the prevalence of hypothyroidism in pregnant women at 12–16 weeks of gestation. Materials and Methods: A cross-sectional study was planned on pregnant women attending the ANC clinic of Outpatient Department of Obstetrics and Gynecology at K.L. E’S Dr Prabhakar Kore Hospital and Medical Research Center Belagavi. Serum thyroid stimulating hormone (TSH) was estimated in the study participants. Serum TSH levels >4.5 ?IU/ml were labeled as hypothyroid pregnant women. Results: In our study, the prevalence of hypothyroidism was observed to be 8.68%. Conclusion: Hence, we conclude that all pregnant women should be screened for hypothyroidism at earlier weeks of gestation.
Quality of life in children with cerebral palsy
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Nanjundappa, N; Krishna, P; B, S; Ghosh, R; K, T.
Background: Cerebral palsy (CP) is the most common motor disability in childhood. Quality of life (QOL) has emerged as an important concept in childhood, especially for children with disabilities. CP has an impact on a child’s capacity to do activities of daily living thus affecting QOL of patients and their families. Aims and Objectives: The objective of present study was to assess the QOL in children with CP. Materials and Methods: In this study, 29 children with CP in the age group of 4–12 years were evaluated for QOL was assessed using CPQOL-Child Primary Caregiver Questionnaire (4–12 years). The questionnaire was completed by one of the parents or their caregiver. Scores for each domain of QOL were converted to a scale ranging from 0 to 100 and analyzed. Results: The scores as reported by the parents were low for each of the domains with maximum effect seen in functioning domain and least in pain domain. Girls had better QOL than boys. The QOL scores were negatively related to the severity of CP which was assessed by gross motor function classification system suggesting that severity of disability had negative impact on QOL. Conclusion: QOL of children with CP was found to be poor and was influenced by age, sex and motor functioning
Pulmonary function tests in compressed natural gas pump workers in Surat city
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Desai, M; Desai, H
Background: Various studies have known abatements in lung function and several other health problems associated with longstanding air pollution exposure. One of the most cost-effective and environmental alternative of conventional fuels (petrol and diesel) is compressed natural gas (CNG). The increasing use of CNG as a fuel (as it is safe and cheap as compare to the conventional fuels) can add one more bug to the list of work-related disease. Aims and Objectives: This study is to evaluate the respiratory functions of CNG pump workers. Materials and Methods: The present study was held on 82 male subjects. The study group included of non-smoking healthy adult males, age group of 20–40 years working in different CNG stations in Surat city for >6 months and 8 h per day. The control group included of non-smoking healthy adult males, age group of 20–30 years working or studying in the Surat Municipal Institute of Medical Education and Research (SMIMER). Results: Out of 82 male subjects, 30 subjects were control and 52 subjects were CNG station workers. The study group comprised of 52 healthy non-smokers in the age group of 20–40 years working in different CNG station in Surat city for >6 months and 8 h/day. The control group comprised of 30 healthy non-smokers males between the age group of 20–30 years working or studying in the SMIMER. Conclusion: In this study, we have not found statistically significant deterioration in pulmonary functions of CNG pump workers when compared to controls.
Wave V threshold among children with delayed speech and language, using brainstem evoked response audiometry – A cross-sectional study
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Mondal, T; Bhattacharya, H; (Das), SM.
Background: Brainstem Evoked Response Audiometry (BERA) is an objective test for audiometric assessment of children. As deprived linguistic skill is often associated with auditory impairment in initial years of life; early diagnosis and interventions are much needed. Aim and Objective: To detect Wave V, in the lowest intensity, as it is a reliable parameter to assess BERA threshold for hearing among different age group of children. Materials and Methods: This cross-sectional study included 250 children (n = 250) with impaired speech and 120 normal children. The case population was divided into four groups according to age – Group 1 (<1 year); Group 2 (1–3 years); Group3 (3–6 years); and Group 4 (6–12 years). Wave V threshold was determined by BERA (measure brainstem auditory evoked potential). Cases were also divided into two categories depending on unilateral or bilateral involvement of ear. Mean threshold of each group was compared with corresponding control group of similar age. The test of significance used was Mann–Whitney U-test. Intragroup comparison was done by Kruskal–Wallis test. Results: In Group 1, 91.7%; Group 2, 100%; Group 3; 88.6%, and Group 4; 85% of children were suffering from bilateral hearing loss. In all the groups, mean threshold was statistically significantly increased in comparison with control group. In intragroup comparison, there was no statistically significant difference of threshold among all the groups of cases in both of the ears. Conclusions: This study identified increased wave V threshold in children with impaired speech of all four groups. Thereby, it indicates the necessity of BERA as screening method.
A study on smart phone use and its perceived health effects among the adolescents attending Medical College and Hospital, Kolkata
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Manna, N; Marak, M; Mukherjee, A; Banerjee, A.
Background: Smartphone usage is gradually escalating among Indian adolescents, which is having adverse consequences on their health and well-being. Awareness regarding adverse health impacts of smartphone usage among adolescents is thus necessary. Aims and Objectives: This study assessed the smartphone usage pattern and perception regarding its health effects among adolescents attending adolescent friendly health clinic (AFHC) at Medical College and Hospital, Kolkata. Materials and Methods: This cross-sectional study was conducted among 187 adolescents from January to March 2023 at AFHC of Medical College and Hospital, Kolkata selected by systematic random sampling technique. Pre-designed self-administered questionnaire was utilized for data collection. Data were analyzed using SPSS software. Factors associated with the duration of smartphone usage were analyzed using the Chi-square test. Results: Smartphone was used by all the study participants (n = 187). A significant proportion has utilized smartphones for >3-year duration, whereas 114 (60.9%) used them for 1–2 h per day and 56 (29.9%) used them for ?3 h per day. The major adverse health impacts of smartphone usage perceived by the participants were eye symptoms (64.2%), headache (50.8%), and neck pain (46.5%). Gender (?2=12.98, df = 2, P = 0.0012), type of residence (?2 = 7.98, df = 2, P = 0.018), and socioeconomic status (?2 = 34.96, df = 2, P < 0.001) were factors significantly associated with the duration of smartphone usage per day. Conclusion: Smartphone should be optimized to protect the physical and mental well-being of adolescents. Motivation and counselling regarding the adverse effects of smartphone usage is should be given the utmost priority. Generating awareness among parents at the community level through field health workers is also the need of the hour.
Pharmacovigilance: How aware are the prescribers?
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) R, SN; S, S.
Background: Adverse drug reactions (ADRs) is one of the important factors contributing to morbidity and mortality among patients and is a major public health burden. Spontaneous ADR reporting plays an important role in detection of ADRs, reducing their incidence and improving patient safety. India has one of the lowest ADR reporting rates in the world. Aim and Objective: The aim of the study was to assess the knowledge, attitude and practice (KAP) of doctors towards pharmacovigilance. Materials and Methods: A KAP questionnaire validated by subject experts was given to the doctors outside the teaching profession within 50 km of Government TD Medical College, Alappuzha, who consented to be a part of the study. The questions were structured to obtain the demographic details of the doctors, their KAP toward pharmacovigilance. No identifiable information regarding the participants was collected and the participants were assured of their confidentiality. A week’s time was given to the participants to answer the questions. Results: During the period of 1 year from June 2019 to May 2020, a total of 121 doctors responded to the questionnaire. The respondents aged from 26 to 67 years with the mean age being 37.31 ± 14.15 years. 94 (77.7%) thought that anyone could report an ADR while 16 (13.2%) thought that only doctors could report ADRs. Only 76 (62.8%) were aware of the existence of National Pharmacovigilance Centre in India. Ninety-eight (81%) did not know how to submit the ADR form to the nearest pharmacovigilance center. A vast majority 99 (81.8%) thought that ADRs to drugs of any system of medicine could be reported, while 20(16.5%) felt that only ADRs to modern medicines need to be reported. Among the factors discouraging doctors from reporting ADRs, lack of training to report an ADR 99 (81.8%) and lack of time during practice 83 (68.5%) were cited as the common reasons. A vast majority 116 (95.9%) had not received any formal training on ADR reporting and 114 (94.2%) opined that they would like to receive a formal training on the same. Conclusion: Doctors were largely aware of pharmacovigilance but had lack of KAP of reporting ADRs and filling up an ADR form. It emphasizes the need for regular mandatory education and training on ADR reporting among healthcare workers, and also the need to run continuous awareness campaigns on spontaneous reporting of ADRs to enhance reporting rate.
Clinicopathological correlation of various prostatic lesions with serum prostate-specific antigen level – A hospital-based cross-sectional study
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Mishra, SKC; Sahu, BK; Kar, SS; Dixit, S; Dash, AP.
Background: The prostate is a male reproductive accessory gland which gives rise to several pathological conditions. The present study aims to study the correlation of histopathology of prostatic diseases with the clinical profile of the patient coming to VSS Medical College (VSSMC), Burla for histopathological reporting of prostatic biopsies. Aim and Objectives: The objectives of this study were as follows: (1) To correlate serum prostate-specific antigen (PSA) level with various clinical and pathological lesions of the prostrate gland, in a Hospital-based sample of Western Odisha population. (2) As the male gender represents almost half of the entire population, to find out different clinicopathological lesions, percentage-wise, so as to know the frequency of occurrence of such lesions. Materials and Methods: Fifty-seven cases of prostatic diseases were recorded in the Department of Pathology, VSSMC, Burla for histopathological examination of prostatic tissue for 2 years from September 2017 to August 2019. All the samples were fixed in 5 ? sections with 10% neutral buffered formalin. Then Hematoxylin and Eosin stain (H and E stain) was used for staining. Appropriate clinical data comprising signs and symptoms, laboratory findings, and serum PSA levels were recorded. Results: The present study, in the beginning, consisted of 64 patients, out of which seven patients were excluded by exclusion criteria, and finally, 57 cases were analyzed. The most prevalent age group for all prostatic diseases was 61–70 years with a mean of 67 years. The majority of the cases (73.67%) were benign mostly benign prostatic hyperplasia (BPH). Prostatic intraepithelial neoplasia (PIN) was 12.29% and malignant cases (all adenocarcinoma) were also 12.29%. All patients showed prostatomegaly. About 50% of cases suggestive of malignancy by digital rectal examination (DRE) were confirmed to be carcinoma by histopathological study. Serum creatinine level was raised in 16.27% of benign and 21.42% of premalignant and malignant conditions. Serum PSA level below 4 ng/mL were all benign and above 10 ng/mL were majority malignant conditions. However, at level 4–10 ng/mL, BPH and PIN cases were overlapped with cases of carcinoma. Conclusion: Benign prostatic hyperplasia is the most commonly encountered prostatic lesion. Serum PSA level <4 ng/mL is associated with benign conditions and more than 10 ng/mL is associated more with carcinomas. Although, investigations such as DRE and serum PSA estimation aid in diagnosis, a definitive diagnosis of benign and malignant lesions of prostate can be made by histopathological study of prostatic biopsies.
Door-to-door health camps versus traditional health camps in rural areas of Himachal Pradesh – A comparative analysis
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Nanda, MS; Chadha, S; Chadha, SC.
Background: Health camps are effective medical intervention, especially in inaccessible terrains. However, because of age, health, and COVID-19 fear, many patients avoid visiting these camps because of crowding. Door-to-door health camps could be a solution to this. National Medical Commission has also introduced early clinical exposure and family adoption for medical undergraduate students. Aim and Objectives: The authors had planned to conduct this research to study the advantage of door-to-door health camps involving medical undergraduate students as camp team members as compared to traditional health camps regarding patient satisfaction and student satisfaction. Material and Methods: This study was done in rural hilly areas of Himachal Pradesh. There were 8 traditional health camps and 8 door-to-door health camps also involving medical undergraduate students organized between August 2022 and November 2022. These camps were analyzed for patients’ satisfaction and students’ satisfaction. Results: Patient satisfaction was much higher in door-to-door camps as compared to traditional health camps. More patients attending door-to-door camps visited our hospital for follow-up. Students were also satisfied participating in door-to-door camps. It also improved their interest in studying medicine. Conclusion: Door-to-door health camps are more beneficial for patients, especially in hilly inaccessible terrain. Involving students in these camps improves their interest in studying medicine and can be beneficial.
Correlation between Bath Ankylosing Spondylitis Disease Activity Index Score and body mass index in the patients suffering with ankylosing spondylitis
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Roy, A; Jayanthi, A; Jaiswal, R; Singh, SK.
Background: Ankylosing spondylitis (AS) is a chronic inflammatory disease of the axial spine that can manifest with various clinical signs and symptoms. Chronic back pain and progressive spinal stiffness are the most common features of this disease. It is an autoimmune disease which also leads to the involvement of skeletal, cardiac, nervous tissues, and other systemic organs. Aim and Objectives: This study was conducted to assess the correlation between the Bath AS Disease Activity Index (BASDAI) score/visual analog scale (VAS) and various age groups in the patients suffering with AS using standard questionnaire. Materials and Methods: Forty-eight AS patients having BASDAI scores of ?4 were included in this study. The height and weight were taken and responses to the standard questionnaire were recorded. BASDAI Score, body mass index (BMI), and VAS were computed. The patients with history of chronic diseases such as hyper/hypothyroidism, diabetes mellitus, and hypertension or the use of any medication such as ?/? blockers, calcium channel blockers, and antiepileptics were excluded from the study. Results: The patients were divided into six different age groups, i.e., 15–20 years, 21–25 years, 26–30 years, 31–35 years, 36–40 years, and 41–45 years. The mean ± SEM values of the BASDAI score in various age groups were 6.8 ± 0.34, 6.3 ± 0.33, 6.2 ± 0.26, 7.1 ± 0.41, 6.5 ± 0.30, and 5.8 ± 0.48, respectively. The mean ± SEM values of VAS are shown in relation to the various age groups, i.e., 15–20 years, 21–25 years, 26–30 years, 31–35 years, 36–40 years, and 41–45 years and the values were 6.88 ± 0.312, 6.58 ± 0.22, 6.55 ± 0.66, 6.00 ± 0.23, 6.72 ± 0.25, and 6.0 ± 0.50, respectively. Conclusion: This study indicates that in the young age group, patients BASDAI score is higher and BMI is lower, and in the older age group, patients BASDAI score is lower and BMI is higher than each other indicating higher disease activity in the younger patients than older patients. An inverse correlation between VAS and age further substantiates our previous finding.
Perception of first MBBS students toward online formative assessment in biochemistry
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Talikoti, P; Vadivel, K; Ansari, MWF; Khubya, D; Vaddadi, V.
Background: The COVID-19 pandemic affected all the educational activities including medical education and there is a substantial shift from direct classes to online platforms.In competency-based medical education (CBME), the formative assessment orchestrates a prominent role in increasing the student’s capacity of learning. This method of teaching guides the students to measure the performance over a period of time and also improves the students’ knowledge gap. Aim and Objectives: The present study was carried to evaluate the perception and attitude of students toward online assessment during the formative assessment in 1st year MBBS degree in biochemistry subject. The study also aimed to assess practical difficulty and feasibility of conducting online assessment as a part of formative assessment as per CBME curriculum. Materials and Methods: The study was conducted on 124 1st year MBBS students and the students were informed about the assessment in 15 days advance. The perception and attitude of the students toward online assessment was done using 20 items structured questionnaire administered through Google forms. The students’ response was measured using 5-point Likert scale. Results: Among the 124 students, 42 (39.6%) were aware about online assessment. About 57.5% of students preferred any type of gadgets such as desktops, laptops, and smart phones. Most of the students 84.5% obtained 50–75% for a total score of 25. Around, 51.9% of students responded that online teaching is more feasible, and 74.5% reported that there is connectivity problem during online platform. In this study, 46.2% online assessment is safe and 41.5% strongly disagree that distraction from home environment did not affect the online assessment. Conclusion: The present study concludes that the students are more interested in MCQ-based question assessment for the knowledge assessment. Further, they opined in favor of online education but with some demerits.
Third trimester HbA1c as a prognostic indicator in the prediction of large-for-gestational age babies in South Indian women with gestational diabetes mellitus: A cross-sectional study
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Pari, N; Devanand, V; S, S; M, VK; S, V.
Background: The prevalence of hyperglycemia first detected during pregnancy is showing an escalating increase in recent years contributed by the increasing obesity prevalence, advanced maternal age at delivery, and the universal screening protocol during the first antenatal visit. There exists a very little data on the role of HbA1c in pregnancy and the results remain inconsistent. There is a need to define diagnostic criteria to predict the adverse perinatal outcomes in gestational diabetes mellitus (GDM). Aims and Objectives: This study was aimed to assess the role of HbA1c as a prognostic indicator of third trimester mean blood glucose in GDM pregnancies and in predicting the birth of large for gestational age (LGA) babies. Materials and Methods: 200 pregnant women with GDM and 200 pregnant women without GDM and their neonates participated in this analytical cross-sectional study. Maternal age, height, weight, BMI, and neonatal birth weight were recorded. Third trimester maternal HbA1c level was analyzed by high-performance liquid chromatography. The association between HbA1c and LGA births was analyzed. Results: The mean HbA1c levels and percentage of LGA births were high in GDM group. Multiple logistic regression analysis showed association between high HbA1c values and LGA births in GDM. A Receiver operating characteristic curve was drawn to derive the optimal cut-off value, sensitivity, and specificity of HbA1c in predicting birth of LGA neonates in GDM. Conclusion: This study shows that high third trimester HbA1c levels in GDM increase the risk of LGA births. Further studies are needed to define standard cut-off values of glycated Hb in each trimester of pregnancy.
Risk factors for extended-spectrum beta-lactamase- and carbapenem- resistant Enterobacteriaceae in patients with urinary tract infection from a tertiary care hospital
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Jadeja, BJ; Khokhar, N; Shrimali, G.
Background: Urinary tract infection (UTI) is a common health problem in both community and nosocomial settings. However, the predisposing factors which are responsible for production of extended spectrum beta-lactamase (ESBL) and carbapenem-resistant Enterobacteriaceae makes the treatment option narrow and cause multidrug resistance. Aim and Objectives: This study demonstrate various risk factors associated with multidrug resistance in Enterobacteriaceae from UTI at tertiary care center in Gujarat. Material and Methods: A retrospective observational study was conducted at a tertiary-care hospital. Urine samples were received from various departments and outpatient department (OPD). Organisms from Enterobacteriaceae group were isolated and identified by various biochemical methods. ESBL and Carbapenemase producing organisms were then processed for Antibiotic susceptibility test as per CLSI guideline. Results: A total of 196 Enterobacteriaceae organisms were isolated from processed urine samples of tertiary care Hospitals. The most prevalent in people aged 45–65 years (36%) followed by those aged 17–30 (22%) years. UTI due to ESBL and Carbapenemase producer are more isolated in female (28%, 11%) as compare to male (16%, 6%). Indoor patients had higher prevalence of ESBL (29%) and carbapenemases (10%) isolation compare to OPD patient (ESBL-15%, Carbapenemases-7%) and among them most common ward was medicine department. The most common predisposing factor was catheterization followed by diabetes mellitus and obstructive uropathy. Conclusion: High prevalence of ESBL and Carbapenemase producing Enterobacteriaceae is found in Indoor patients than OPD patients. Most of these patients are from Medicine department. Catheterization is the most common risk factor associated with ESBL and carbapenemase producing organism.
Functional outcomes of patients with comminuted radial head fracture undergoing radial head arthroplasty
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Ajrawat, SS; Mal, JJB; Talwar, K; Goyal, C.
Background: The functional stability of the elbow joint can be effectively restored in acute care for comminuted radial head fractures (RHFs) complicated with secondary ligamentous or bony injuries through the use of a metallic radial head implant. Aims and Objectives: This study aimed to evaluate the efficiency of modular metallic radial head implant EVOLVE® prosthesis in restoring the functional range of motion and elbow joint stability in acute care. Materials and Methods: A prospective observational study was conducted in the department of orthopedics at a tertiary-level care hospital in North India from April 2021 till March 2022. All consecutive patients above 18 years of age, with comminuted closed RHF, were included in the study. All underwent modular metallic head radial head implantation. The Mayo Elbow Performance Score (MEPS) was used to measure functional outcomes. Results: We observed that MEPS at 1-month follow-up was 81.54 ± 11.18, which improved significantly at the 3rd-month follow-up to 87.24 ± 12.42 (P < 0.001). On the next follow-up at the 6th month, MEPS increased further to 92.14 ± 7.36, P < 0.001. At the final follow-up at the 6th month, MEPS was graded as excellent for 80%, good for 12%, fair for 4%, and poor for 4%. One patient had complex regional pain syndrome and one had joint stiffness. Conclusion: The use of a modular radial head prosthesis has shown promise in treating comminuted RHF by re-establishing elbow joint stability in acute setting. This study demonstrated promising short-to-midterm results for the modular radial head arthroplasty.
Assessment of risk of diabetes in medical students using the Indian diabetes risk score
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Gakhar, A; B, S; N, N.
Background: Diabetes is one of the most common causes for morbidity and mortality. Among which type 2 diabetes is the most rampant in which body does not make synthesize or utilize insulin effectively insulin is a hormone that helps the body cells to utilize glucose for energy production. Deficiency of insulin leads to high level of glucose in the plasma. Sustained high blood glucose level for a longer duration can lead to serious problems in heart, eyes, kidneys, and nerves. This may lead to complications such as neuropathy, retinopathy, nephropathy, and atherosclerosis. Aim and Objectives: The aim of this study was to identify the risk of diabetes in medical students. Materials and Methods: One hundred medical students in the age group of 18–21 years were screened for prediabetic state using the diabetic risk score and were statically analyzed. Results: Out of 100 students, 57 were found to have low risk, 41 moderate risk, and only two had high risk of diabetes. The results of the present study showed that 49% of students were indulged in mild activity and 25% of the students were not involved in any kind of physical activity. Conclusion: Lack of physical exercise was found to be the major risk factor for diabetes among medical students, and hence, it is suggested that medical students should also stress on physical exercise along with studies.
Assessment of mental health status in male and female medical students of 1st-year MBBS
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) N, KM; Devulapally, Y; S, P; J, S.
Background: There is an increase in mental health issues throughout the globe. The major age group that was affected is young adults. Although from the outside, it appears that college life is very happy and enjoyable. However, the actual scenario is different. Aims and Objectives: The present study was undertaken to assess the mental health status of male and female medical students in the 1st year. Materials and Methods: A total of 150 male and female young adults, studying 1st-year MBBS, were part of the study after obtaining informed consent. Standard questionnaires were used to assess the mental health of the students. Results: Out of 150 students, 140 students responded to the study. Anxiety scores were significantly higher in females when compared to males (P < 0.05). Insomnia was significantly higher in females when compared to males (P < 0.01). Eating disorder scores were higher in females when compared to males (P < 0.0001). Depression, anxiety, and stress scores were significantly higher in females when compared with males. Distress was significantly higher in females when compared to males (P < 0.0001). Conclusion: The study results explain that female students’ mental health was in borderline and there is a strong need to counsel them and train them with coping methods. The study highlights a strong need for the future studies.
Omeprazole-induced cardiac arrhythmia – A case report
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Bhandari, V; Singh, N; Dureja, S.
Omeprazole, a Proton pump inhibitor, is widely prescribed in patients with chronic gastroesophageal reflux. Patients continue to use omeprazole for long period of time even without the supervision of the doctor. The authors report a 50-year-old male patient with a 5-year history of omeprazole use, who complained of chest discomfort. ECG on admission showed atrial fibrillation. Laboratory findings showed hypomagnesaemia, hypocalcaemia, and hypokalemia. The case report emphasizes the importance of patient education regarding the use and adverse drug reactions of the prescribed medications.
Assessment of depression, anxiety, and stress in COVID-19-positive patients with chronic illness – A comparative study
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Sukumaran, S; Achambattu, S.
Background: The physical, social, and emotional difficulties posed by chronic illnesses can result in depression, anxiety, and stress, which are common mental health conditions. The severe acute respiratory syndrome-CoV-2 virus, which causes the novel respiratory illness COVID-19, has had a significant impact on the global population, especially those who already have underlying chronic illnesses. In this study, we tried to evaluate the psychological stress, depression, and anxiety experienced by COVID-positive patients with and without chronic health conditions, while they are quarantined as a result of the COVID-19 pandemic. Aim and Objectives: The objectives of this study were to assess the prevalence of depression, anxiety, and stress among COVID-positive patients and to compare the prevalence of depression, anxiety, and stress among COVID-positive patients with and without chronic illness in a district in North Kerala. Materials and Methods: This observational and cross-sectional study was carried out in a district in the northern state of Kerala, India. A study population of 251 individuals who had positive COVID tests participated in the study. Out of this group, 117 people had chronic health problems such as high blood pressure, diabetes, and heart disease, while the remaining 134 people were without any chronic illness. An online questionnaire including sociodemographics and depression, anxiety, and stress scale -21 was used to evaluate depression, anxiety, and stress among the participants. Results: COVID patients with chronic illnesses experienced severe depression at a rate of 77.8% compared to 20.1% in those without any chronic illness. Patients with chronic illnesses who tested positive for COVID-19 also experienced severe anxiety in 77.8% of cases, compared to the 23.8% of really severe cases of anxiety among COVID patients who do not have any chronic illnesses. Moderate stress levels were observed in 76.06% of COVID patients with chronic illness when compared to 22.4% in those with no comorbidities. Conclusion: According to the study’s findings, people with chronic illnesses experience higher levels of stress, anxiety, and depression than those who do not have those conditions. The existence of such a high prevalence and severity of psychological issues among quarantined patients with COVID-19 underscores the need for serious attention to the mental health status of these patients.
Prevalence of internet gaming disorder among medical students at medical college in Jamnagar, Gujarat
(Mrs Dipika Charan of MedScience (India) Publications, 2023-06) Vala, NH; Kataria, AN; Sorani, AM.
Background: Smartphone usage became drastically increased in the past two decades. Spending abnormally more time playing games can lead to development of internet gaming disorder (IGD) which leads to negative impact on health and lifestyle. Aim and Objectives: The aim of this study was to find out the prevalence of IGD and smartphone usage patterns in medical students. Materials and Methods: The study was held in M. P. Shah Government Medical College in Jamnagar. Total 206 1st year medical students were included for this study. Pre-validated self-made questionnaire and pre-structured IGD-20 questionnaire were used in this study. Results: The prevalence of IGD in medical students is 1.46%. In male population, the prevalence of IGD was higher (1.6%) compared to female population (1.23%). Conclusion: IGD can be a great disaster if remain unnoticed. It can change one’s lifestyle gradually. Preventive measures such as parental locking system and strong rules for mobile phone use in university hours should be implied.

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