Browsing by Author "Pandey, Vivek"
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Item Localized Pigmented Villonodular Synovitis of Knee: A Mimicker.(2016-06) Senthil, Vishnu; Madi, Sandesh; Pandey, Vivek; Acharya, KiranPigmented villonodular synovitis is a benign neoplastic condition arising from the synovium. The synovium is pigmented (loaded with increased mitochondria siderosomes), metaplatic, pedicled or non-pedicled, and hypertrophied. It commonly arises from mensicocapsular junction. It presents as a localized or diffuse variety. Localized variety presents with locking, effusion, pain, reduced range of motion, palpable mass, or pain over the joint line which mimics different pathological conditions. We present a case of localized pigmented villonodular synovitis which led to diagnostic dilemma and mimicked common pathological conditions. Very few case reports are reported in which the lesion is only diagnosed with arthroscopy when other imaging and clinical findings are misleading.Item Uterine Fibroid: Isolation, Culture and Characterization(SB Publications, 2019-07) Pandey, Vivek; Rani, Anjali; Dubey, Pawan K.Present study was carried out to establish uterine fibroid primary culturesystem for screening of natural/synthetic compounds against uterine fibroid. For invitro culture, enzymatic isolation method was used. To characterize, histochemistry (H& E, Masson’s Trichrome and Periodic Acid Schiff) staining and immunocytochemistryusing marker antibodies (Versican) were performed in vitro. Uterine fibroid tissueshowed much intense staining of Masson’s Trichrome and Periodic Acid Schiff stain ascompared to adjacent myometrium tissue. The primary cultured cells showedsignificantly higher proliferation, sub-culture efficiency and expression of Versicanprotein. In conclusion, our results suggest that in vitro cultured uterine fibroid cells mayoffer a suitable alternative model to evaluate natural or synthetic compounds havingantitumor properties for uterine fibroid treatment.