Sunanchaikarn, SrunthronTheamboonlers, ApiradeeChongsrisawat, VoranushYoocharoen, PornsakTharmaphornpilas, PiyanitWarinsathien, PorpitSinlaparatsamee, SupakarnPaupunwatana, SirirajChaiear, KasempornKhwanjaipanich, SawanPoovorawan, Yong2009-05-272009-05-272007-12-27Sunanchaikarn S, Theamboonlers A, Chongsrisawat V, Yoocharoen P, Tharmaphornpilas P, Warinsathien P, Sinlaparatsamee S, Paupunwatana S, Chaiear K, Khwanjaipanich S, Poovorawan Y. Seroepidemiology and genotypes of hepatitis C virus in Thailand. Asian Pacific Journal of Allergy and Immunology. 2007 Jun-Sep; 25(2-3): 175-82http://imsear.searo.who.int/handle/123456789/36810Published by the Allergy and Immunology Society of Thailand.HCV can be classified into 6 major genotypes based on the phylogenetic analysis of the genomic sequences. The 3 major genotypes found in Thailand are 3, 1 and 6, respectively. In 2004, an epidemiological survey was carried out to evaluate the seroprevalence of HCV infections among populations aged 2-60 years in four provinces of Thailand, representing the North, Northeast, Center and South of the country, respectively. One hundred and twenty five out of 5,825 serum samples (2.15%) were positive for anti-HCV by ELISA. Fifty eight out of 100 anti-HCV positive samples (58.0%) were positive by RT-PCR of the 5'UTR. The core region of 45 representative samples was sequenced allowing classification into genotype variants 1a (6.7%), 1b (26.7%), 2a (2.2%), 2c (2.2%), 3a (51.1%), 3b (2.2%) and 6 (8.9%). This information might be crucial for public health surveillance and prevention of HCV infection.engAdolescentAdultChildChild, PreschoolFemaleGenotypeHepacivirus --geneticsHepatitis C --epidemiologyHepatitis C Antibodies --bloodHumansInfantMaleMiddle AgedMolecular Sequence DataPhylogenySeroepidemiologic StudiesThailand --epidemiologyJournal Article