Srivastava, SSeth, P KSrivastava, S P2009-05-282009-05-281992-05-01Srivastava S, Seth PK, Srivastava SP. Effect of styrene on testicular enzymes of growing rat. Indian Journal of Experimental Biology. 1992 May; 30(5): 399-401http://imsear.searo.who.int/handle/123456789/62877Effect of styrene (100 or 200 mg/kg body wt/day) for 60 days was observed on testicular enzymes of postnatally maturing rats. A significant decrease in epididymal spermatozoa count was observed only at 200 mg/kg body weight dose. Activities of testicular sorbitol dehydrogenase and acid phosphatase decreased while activities of lactate dehydrogenase, beta-glucuronidase, glucose-6-phosphate dehydrogenase, and gamma-glutamyl transpeptidase significantly increased only in animals exposed to styrene at a dose of 200 mg/kg body weight. The results suggest that exposure to high dose of styrene during developmental period alters the activities of enzymes associated with specific cell type of testis.engAnimalsDose-Response Relationship, DrugMaleRatsRats, Wistar --growth & developmentSperm Count --drug effectsStyreneStyrenes --administration & dosageTestis --drug effectsJournal Article