Darakshan, AnjumAmitava, Abadan K2011-12-262011-12-262010-09Darakshan Anjum, Amitava Abadan K. Cut and paste: A novel method of re-attaching rectus muscles with cyanoacrylate during recessions in strabismus. Indian Journal of Ophthalmology. 2010 Sept; 58(5): 395-398.http://imsear.searo.who.int/handle/123456789/136095Aim: Bio-adhesives like cyanoacrylate offer an alternative to sutures to attach tissues, including in ophthalmology. This prospective trial evaluated the suitability and bio-tolerance of iso-amyl cyanoacrylate in rectus muscle recession surgery for strabismus. Materials and Methods: We randomized one eye in each of 10 cases of bilateral horizontal rectus recessions to 6/0 polyglactin and the other to iso-amyl-cyanoacrylate. We compared time to reattachment (from disinsertion), complications and inflammatory scores (0 to +3: nil, mild, moderate and severe) on Day One, at two and at four to six weeks post surgery. Results: There were no significant group differences in inflammatory scores (Wilcoxon, all values of P>0.05). All attachments held firm. Gluing took significantly longer by 5.24±1.91 min (95% CI for difference: 3.87-6.61). There were no complications. Conclusion: We feel that although it takes marginally longer, iso-amyl cyanoacrylate offers an effective and safe alternative to sutures for muscle recession in strabismus surgery. Since it is cheaper (vs. polyglactin) and offers multi-use possibility it may also prove to be cost-effective.enBioadhesivescyanoacrylatepolyglactinrecessionstrabismusAdolescentAdultChildCyanoacrylates --therapeutic useHumansInflammation --etiologyIntraoperative CareOculomotor Muscles --surgeryOphthalmologic Surgical Procedures --adverse effectsPolyglactin 910 --therapeutic usePostoperative ComplicationsStrabismus --drug therapyStrabismus --surgerySuturesTime FactorsTreatment OutcomeYoung AdultCut and paste: A novel method of re-attaching rectus muscles with cyanoacrylate during recessions in strabismus.Article