Chakravarty, NilotpalSuhag, VirenderBs, Sunita2019-11-252019-11-252019-09Chakravarty Nilotpal, Suhag Virender, Bs Sunita. Clinico-epidemiological Profile Of Patients With Gynaecological Malignancies Being Followed-up At A Radiation Oncology Department Of A Tertiary Care Government Institute Of India. Indian Journal of Applied Research. 2019 Sep; 9(9): 9-112249-555Xhttp://imsear.searo.who.int/handle/123456789/185155Background: Gynaecological malignancies constitute a major burden of cancer-related morbidity and mortality amongst females in developing countries including India. Aims and objectives: The study was conducted to study the clinical and morphological characteristics of patients having gynaecological malignancies and treated by radiotherapy with or without chemotherapy, now under follow-up. Study design: Aretrospective observational study in a tertiary care hospital of government set-up over 2 year period. Observations: A total of 3120 patients who reported for follow-up were included, of which 394 patients were of gynaecological malignancies. Carcinoma (Ca) Cervix followed by Ca endometrium were the most common sites (76% and 16% respectively). The most common age group was 7th decade. 33% patients with locally advanced cervical cancer were found to have paraaortic lymphadenopathy on presentation warranting extended field radiotherapy (RT). 73% of locally advanced ca cervix patients received 5 or more cycles of weekly chemotherapy (CT) with Cisplatin. 68% patients were disease-free at the time of follow-up. 11% patients were referred for palliative chemotherapy. 17% patients required hospitalization for symptomatic care during followup. Conclusion: Concurrent chemoradiation is an acceptable and well-tolerated modality of treatment for locally advanced gynaecological malignancies. Multimodal treatment and good collaboration between allied specialists is recommended.Gynaecological malignanciescancer cervixradiotherapy (RT)chemoradiotherapy (CTRT)toxicitiesJournal ArticleIndiaMD DNB Radiation Oncology, HOD Radiation Oncology, Army Hospital (R&R), Delhi Cantt, Delhi-110010, IndiaMD DNB Radiation Oncology, HOD Radiation Oncology, Command Hospital (SC) Pune-411040, IndiaMD DNB Pathology, Professor Pathology, Armed Forces Medical College (AFMC), Pune-411040