Kandalkar, BShah, VShet, T2001-07-252009-05-292001-07-252009-05-292001-07-25Kandalkar B, Shah V, Shet T. Desmoplastic astrocytoma of infancy--a case report. Indian Journal of Pathology & Microbiology. 2001 Jul; 44(3): 329-32http://imsear.searo.who.int/handle/123456789/75888Desmoplastic cerebral astrocytoma of infancy (DCAI) is a rare tumor which shows spindle cells embedded in an extremely desmoplastic stroma. We describe a case of DCAI seen in the frontoparietal region of brain in a three-month-old infant. Microscopically classic histology of DCAI was seen. On immunohistochemistty the tumor showed strong Vimentin, S-100 and Glial Fibrillary Acidic Protein (GFAP) positivity. The brain adjacent to the tumor-showed multi-cystic transformation and the tumor formed a solid area in the wall of this cystic structure. This adjacent brain showed mild disarray of architecture and gliosis. Three months after surgery this infant was alive and well.engAstrocytoma --metabolismBrain Neoplasms --metabolismGlial Fibrillary Acidic Protein --metabolismHumansInfantS100 Proteins --metabolismVimentin --metabolismCase Reports