Dutta, HSengupta, MGhosh, ASengupta, CDe, A U1991-06-012009-05-271991-06-012009-05-271991-06-01Dutta H, Sengupta M, Ghosh A, Sengupta C, De AU. Effect of lignocaine on blood lipid in relation to partition coefficient and biological activity. Indian Journal of Biochemistry & Biophysics. 1991 Jun; 28(3): 210-3http://imsear.searo.who.int/handle/123456789/26591To correlate lipophilicity of lignocaine with changes in lipid composition of blood as a result of in vitro incubation with the drug, phosphorus content and fatty acid compositions of blood lipids before and after lignocaine treatment have been compared with those of a standard phospholipid, lecithin, under similar conditions of drug treatment. The change in fatty acid constituents has been correlated with the biological activity (both therapeutic and toxic) of lignocaine.engAnimalsChromatography, GasChromatography, Thin LayerFatty Acids --analysisFatty Acids, Nonesterified --bloodGoatsLidocaine --pharmacologyLipids --bloodPhospholipids --bloodJournal Article