Chattopadhyay, SBiswas, TChakraborty, BMukherjee, TGhosh, PMondal, R2019-11-042019-11-042019-07Chattopadhyay S, Biswas T, Chakraborty B, Mukherjee T, Ghosh P, Mondal R. Sero-prevalence of Rubella Antibodies in Pregnant Women with Bad Obstetric History Attending A Rural Tertiary Care Hospital in West Bengal, India. International Journal of Medical and Dental Sciences. 2019 Jul; 8(2): 1749-17532454-89522320-1118http://imsear.searo.who.int/handle/123456789/183631Background: Rubella infection in pregnant mothers is of great concern as it acts as a teratogen causing abortions, still births, intra-uterine foetal deaths and multiple birth defects. In India, rubella causes significant bad obstetric pregnancy outcome including congenital deformities due to lack of proper surveillance and immunization coverage with rubella vaccination. Aim: To determine Sero-prevalence of rubella IgM and IgG antibodies in Bad Obstetric History (BOH) pregnant women in Tertiary Rural Medical College in Eastern India. Materials and Methods: Cross sectional study was conducted from 1st January 2017 to 31st March 2017 on sera of 100 antenatal mothers with bad obstetric history aged between 20-40 years of age group with pregnancy of ≥18 wks. Rubella IgM and IgG antibodies were assessed by ELISA. Statistical Analysis: Percentage, proportions and ᵡ2 test were applied. Results: Eleven per cent (11%) sero-prevalence for IgM antibodies and 54% for IgG antibodies was observed with maximum sero-positivity among 20-25 years mothers. Repeated abortions were the commonest pregnancy outcome. Conclusion: All antenatal cases should be routinely screened for rubella, so that early diagnosis will help in proper management and foetal outcome and strong recommendation for universal coverage of MMR in early age group of children.Antenatal MothersBad Obstetric HistoryIgM & IgG AntibodiesRecurrent AbortionRubellaMedical MicrobiologyJournal ArticleIndiaAssistant Professor, Department of Microbiology, Burdwan Medical College and Hospital, Purba Barddhaman – 713104, West Bengal, India; dr.saswatichattopadhyay@gmail.comAssociate Professor, Department of Microbiology, IPGME&R, Kolkata – 700020, West Bengal, India; dr.tanusribiswas@rediffmail.comAssistant Professor, Department of Microbiology, R. G. Kar Medical College, Kolkata – 700004, West Bengal, India; bipasa_doc@yahoo.co.inAssistant Professor, Department of Microbiology, Burdwan Medical College and Hospital, Purba Barddhaman – 713104, West Bengal, India; tmukherjee2008@gmail.comAssistant Professor, Department of Microbiology, Burdwan Medical College and Hospital, Purba Barddhaman – 713104, West Bengal, India; purbashaghosh02@gmail.comAssistant Professor, Department of Community Medicine, Burdwan Medical College, Purba Bardhaman 713104, West Bengal, India; rastonmondal@rediffmail.com