Reddy, D NageshwarRao, G VSriram, P V J2002-11-282009-05-292002-11-282009-05-292002-11-28Reddy DN, Rao GV, Sriram PV. Efficacy and safety of oral sodium phosphate versus polyethylene glycol solution for bowel preparation for colonoscopy. Indian Journal of Gastroenterology. 2002 Nov-Dec; 21(6): 219-21http://imsear.searo.who.int/handle/123456789/64889OBJECTIVE: To assess the acceptability, safety and effectiveness of an oral sodium phosphate solution (Exelyte) for colon preparation prior to colonoscopy, compared with a polyethylene glycol solution (Peglec). METHOD: A colonoscopist-blinded, prospective, randomized, observational clinical study. PATIENTS: One hundred patients undergoing colonoscopy for various indications were randomized (n = 50 each) to receive either 90 mL of oral sodium phosphate mixed with 300 mL clear liquid and then consume about 4-5 glasses of water, or 2 liters of polyethylene glycol solution. RESULT: Sodium phosphate showed a safety profile similar to that of polyethylene glycol. However, patients tolerated it better. The colonoscopist reported similar cleansing of bowel in both groups. CONCLUSION: Oral sodium phosphate is well tolerated, is safe and provides bowel cleansing similar to that with a polyethylene glycol solution.engAdministration, OralAdultAgedAged, 80 and overColonic Diseases --diagnosisColonoscopyEnema --methodsHumansMaleMiddle AgedPhosphates --administration & dosagePolyethylene Glycols --administration & dosageProspective StudiesClinical Trial