Ramzan, MohammedYadav, Satya Prakash2016-01-192016-01-192014-05Ramzan Mohammed, Yadav Satya Prakash. Langerhans Cell Histiocytosis Presenting as Isolated Mediastinal Mass in an Infant. Indian Pediatrics. 2014 May; 51(5): 397-398.http://imsear.searo.who.int/handle/123456789/170620Background: Isolated mediastinal involvement in Langerhans cell histiocytosis (LCH) has been rarely reported. Case characteristics: A 3-month-old boy presented with history of low grade intermittent fever, cough and noisy breathing for 2 weeks. Observation: A chest X-ray showed massive mediastinal widening. Biopsy of the mass confirmed LCH. Outcome: Patient is doing well after one year of treatment with LCH III protocol. Message: Langerhans cell histiocytosis should be considered in differential diagnosis of mediastinal mass in infants.enCancer chemotherapyHistiocytosisMediastinal wideningArticle