Agboatwalla, MIsomura, SAkram, D SIsihara, YSakae, KYamashita, TNishuo, O1995-05-012009-05-301995-05-012009-05-301995-05-01Agboatwalla M, Isomura S, Akram DS, Isihara Y, Sakae K, Yamashita T, Nishuo O. Enteric viral infections in pre-school children in Karachi, Pakistan. Indian Journal of Pediatrics. 1995 May-Jun; 62(3): 345-51http://imsear.searo.who.int/handle/123456789/81570A prospective study was conducted in Karachi, Pakistan on the virology of enteropathogens excreted by children with acute gastroenteritis and the results were compared with a control group of healthy children. Rotavirus and Adenovirus detection was done using ELISA techniques, while enterovirus isolation was done by virus culture. In 1990, 12.3% children with acute watery diarrhoea excreted rotavirus, as compared to 24.4% children in 1991. None of the healthy children excreted adenovirus 40 and 41. Preliminary results of 1992 revealed that rotavirus was seen in 13% of children with acute watery diarrhoea and adenovirus in 10% of children. Enteroviruses were isolated in the same frequency in all three groups i.e. children with acute watery diarrhoea, children with poliomyelitis and healthy children. Non-polio enteroviruses were excreted in 50-52% in all the 3 groups. The rate of enterovirus excretion is much higher than seen in other developed countries and is the same in children with diarrhoea and healthy children.engAcute DiseaseAdenovirus Infections, Human --epidemiologyCase-Control StudiesChild, PreschoolDiarrhea --epidemiologyEnterovirus Infections --epidemiologyHumansInfantInfant, NewbornPakistan --epidemiologyPoliomyelitis --virologyProspective StudiesRotavirus Infections --epidemiologyJournal Article