Bansod, RChandak, RGotekar, SSathawane, ROokalkar, DLanjekar, A.2025-08-132025-08-132025-06Bansod R, Chandak R, Gotekar S, Sathawane R, Ookalkar D, Lanjekar A.. Marring effects of chronic kidney disease on the oral cabinet: a case control study . International Journal of Clinical Trials. 2025 Jun; 12(2): 87-932349-32402349-3259https://imsear.searo.who.int/handle/123456789/253744Background: Patients with kidney diseases are an extremely delicate group of patients. Hence a cooperation between a dentist and a nephrologist is very imperative for a suitable dental treatment of such patients. This would lead to avoidance of severe complications of kidney diseases rendering early diagnosis of the disease. To study the effect of chronic kidney disease on the oral mucosa and inspecting the wide spectrum of oral manifestations in patients with chronic kidney disease. Methods: The study group consisting of 57 participants including the control group above the age group of 20 years was selected. Patients were selected from a private dialysis center. The study population was divided randomly into three groups, each group consisting of 19 participants. Group I consisted of 19 recently diagnosed chronic renal failure patients who were not on dialysis. Group II consisted of 19 chronic renal failure patients who were on dialysis and Group III consisted of 19 normal subjects as control group. Results: Various oral manifestations are peculiar of chronic kidney disease and thus the oral cavity should be thoroughly examined in order to inspect these oral findings and treat them accordingly. In the present study oral manifestations such as drug induced melanosis, periodontitis, gingival enlargement, leukoplakia, angular cheilitis, mucosal pallor and oral ulcerations were seen in the study subjects Conclusions: The oral cavity of chronic kidney disease patients may display a number of oral manifestations which at right time if treated properly may reduce the risk of spread of infections.Chronic kidney diseaseCKDOral manifestationsPeriodontitisJournal ArticleIndiaDepartment of Oral Medicine & Radiology, SDKS Dental College & Hospital, Nagpur, Maharashtra, IndiaSAHS, DMIHER, Wanadongri, Nagpur, Maharashtra, IndiaDepartment of Ophthalmology, Government Medical College, Bhandara, Maharashtra, IndiaDepartment of Oral Medicine & Radiology, SDKS Dental College & Hospital, Nagpur, Maharashtra, IndiaAshwini Kidney Dialysis Centre, Nagpur, Maharashtra, IndiaAshwini Kidney Dialysis Centre, Nagpur, Maharashtra, India