Bajaj, GRattan, AAhmad, P1989-10-012009-05-271989-10-012009-05-271989-10-01Bajaj G, Rattan A, Ahmad P. Prognostic value of 'C' reactive protein in tuberculosis. Indian Pediatrics. 1989 Oct; 26(10): 1010-3http://imsear.searo.who.int/handle/123456789/12448'C' reactive protein (CRP) levels were determined in 100 cases of tuberculosis and 30 age and sex matched children. Serial estimations, one and 3 to 6 months after initiation of therapy was done in 81 and 41 of these patients, respectively. Mean initial levels of CRP in tuberculosis group was 18.52 micrograms/ml while in the control group it was 2.77 micrograms/ml (p less than 0.001). The elevated CRP levels fell significantly to 5.93 micrograms/ml after one month of treatment (p less than 0.001) and by 3 to 6 months of treatment had fallen to normal values. The fall in CRP levels correlated with clinical response. It is concluded that CRP can serve as a sensitive indicator of activity of the disease and the return to normal values of initially elevated CRP levels may indicate a good therapeutic response.engC-Reactive Protein --analysisChildHumansPrognosisTuberculosis --bloodJournal Article