Singh, MohkamGupta, Rakesh Kumar2019-11-162019-11-162019-04Singh Mohkam, Gupta Rakesh Kumar. Importance of Synovial Biopsy of Knee Joint in the Diagnosis of Various Joint Disorders. International Archives of BioMedical and Clinical Research. 2019 Apr-Jun; 5(2): 48-512454-98942454-9886http://imsear.searo.who.int/handle/123456789/184181Background: Rheumatoid arthritis hardly causes diagnostic problems when presented typically. Generally, difficulties arise when atypical clinical presentation is related with non-contributory preliminary investigations. Arthritis is an important cause of morbidity. Methods: In this study 60 total numbers of cases were included. This study was conducted in the Department of Orthopedics in K M Medical College & Hospital, Mathura. The duration of study was over a period of one year. Result: This result revealed that 40% cases were suffering from Chronic non -specific synovitis, 31.6% Rheumatoid arthritis, 6.7% Septic Arthritis & Osteoarthritis, 5% Gout & Synovial (osteo) chondro mitosis,3.3% Synovial sarcoma, 1.6% Giant cell tumor of tendon sheath Conclusion: This study concludes that Diagnostic method like immune-histological methods can be used to eliminate the “non-specificity”. It is also useful in achieving a better specific diagnosis.Synovial BiopsyHisto-pathologial FindingsRheumatoid FactorJournal ArticleIndiaAssistant Professor, Dept. of Orthopaedics, Krishna Mohan Medical College & Hospital, Mathura, U.P, India.Assistant Professor, Dept. of Orthopaedics, Krishna Mohan Medical College & Hospital, Mathura, U.P, India.