Engiz, OzlemBerberoglu, MerihSiklar, ZeynepBilir, PelinOcal, Gonul2012-10-232012-10-232009-09Engiz Ozlem, Berberoglu Merih, Siklar Zeynep, Bilir Pelin, Ocal Gonul. Treatment of autonomous ovarian follicular cyst with long-term anastrozole therapy. Indian Journal of Pediatrics. 2009 Sept; 76(9): 950-951.http://imsear.searo.who.int/handle/123456789/142378Functional follicular ovarian cysts are frequently reported in girls with peripheral precocious puberty (PP). These cysts are usually self-limiting and resolve spontaneously. Several drugs like antiestrogens (tamoxifen) and new aromatase inhibitors are seldom used for treatment. Here we report a girl with peripheral PP who presented with unilateral enlargement of the ovary and a recurrent autonomous ovarian cyst. No skin pigmentation or bone anomaly was noted. The patient was successfully treated with anastrozole, a highly selective aromatase inhibitor. No adverse reaction was noted. Anastrozole is a safe and tolerable drug especially used to suppress estrogen action.enPeripheral precocious pubertyAutonomous ovarian cystAnastrozoleMcCune Albright syndromeAromatase Inhibitors --therapeutic useChildFemaleHumansNitriles --therapeutic useOvarian Cysts --drug therapyPuberty, Precocious --drug therapyRecurrenceTriazoles --therapeutic useArticle