KUMARI, RUCHIKUSHWAH, ANJALIKHARAT, AVINAVIGNAN, NARLAPATIOJHA, SIDDHARTHMISHRA, AKASHMISHRA, PAROMA2024-09-242024-09-242024-04KUMARI RUCHI, KUSHWAH ANJALI, KHARAT AVINA, VIGNAN NARLAPATI, OJHA SIDDHARTH, MISHRA AKASH, MISHRA PAROMA. SICKLE CELL DISEASE IN JHABUA AND KHARGONE DISTRICT: UNVEILING PREVALENCE AND SEVERITY . International Journal of Pharmacy and Pharmaceutical Sciences . 2024 Apr; 16(4): 57-600975-14912656-0097https://imsear.searo.who.int/handle/123456789/231171Objective: To assess the prevalence among Sickle cell disease (SCD) affected individuals emphasizing the neglected health challenges in various tribes.Methods: Cross-sectional, observational study was conducted during the district residency program for 9 mo. The data has been collected from the record room of patients diagnosed with Sickle cell Anemia. Statistical analysis was done using Microsoft Excel.Results: A total of 295 patients’ data revealed demographic skew toward Jhabua (50%), with Sickle cell anemia diagnosed at the mean age of 23±3.9. Most patients (72.3%) were Hindu, with Bhil and Bhilaya tribes having higher frequencies. Symptoms varied; 94% had Sickle cell trait, 16.3% had sickle cell disease, and 60% experienced painful crises. Treatment included prophylactic care for all, 37.57% required blood transfusions and 29.7% were on hydroxyurea.Conclusion: The study underscores the significant SCD burden and the need for heightened awareness and targeted interventions in socio-economically disadvantaged tribal regions to mitigate the impact of SCD.Sickle cell diseasePrevalenceTribal populationTreatment patternDisease burdenJournal ArticleIndiaDepartment of Pharmacology, Mahatma Gandhi Memorial Medical College, Indore, Madhya Pradesh 452001, IndiaDepartment of Pharmacology, Mahatma Gandhi Memorial Medical College, Indore, Madhya Pradesh 452001, IndiaDepartment of Pharmacology, Mahatma Gandhi Memorial Medical College, Indore, Madhya Pradesh 452001, IndiaDepartment of Pharmacology, Mahatma Gandhi Memorial Medical College, Indore, Madhya Pradesh 452001, IndiaDepartment of Pharmacology, Mahatma Gandhi Memorial Medical College, Indore, Madhya Pradesh 452001, IndiaDepartment of Pharmacology, Mahatma Gandhi Memorial Medical College, Indore, Madhya Pradesh 452001, IndiaDepartment of Pharmacology, Mahatma Gandhi Memorial Medical College, Indore, Madhya Pradesh 452001, India