Mukhopadhyay, R PChandra, A L2009-05-282009-05-281990-06-01Mukhopadhyay RP, Chandra AL. Keratinase of a streptomycete. Indian Journal of Experimental Biology. 1990 Jun; 28(6): 575-7http://imsear.searo.who.int/handle/123456789/56770Keratinase produced from Streptomyces Sp.A11 decomposed human hair, chicken feather, wool, silk and pure keratin extracted from human epidermis. Purification of the enzyme by DEAE-cellulose column chromatography resulted in 7.5-fold increase in activity relative to the activity of the culture filtrate. The enzyme was inducible, extracellular, homogeneous with a molecular weight of 49,000. The enzyme activity was inhibited by reduced glutathione, phenylmethyl sulphonyl fluoride and 2-mercaptoethanol.engAnimalsChickensFeathers --metabolismGlutathione --pharmacologyHumansKeratins --metabolismMercaptoethanol --pharmacologyMolecular WeightPeptide Hydrolases --isolation & purificationPhenylmethylsulfonyl Fluoride --pharmacologyStreptomyces --enzymologyJournal Article