Gandhi, T PModh, P RShah, G FPatel, V C1978-07-012009-06-011978-07-012009-06-011978-07-01Gandhi TP, Modh PR, Shah GF, Patel VC. Local anaesthetic activity of some sec-amino-N-(aryl-aralkyl)-ethyl acetamides. Indian Journal of Physiology and Pharmacology. 1978 Jul-Sep; 22(3): 317-20http://imsear.searo.who.int/handle/123456789/108636Six basic amides were screened for local anaesthetic activity and compared with procaine and lignocaine. Amongst the basic amides screened, piperidino-N-(alpha-4-ethoxy phenyl- beta-phenyl) ethyl and Diethylamino-N (alpha-4-ethoxy- beta-phenyl) ethyl acetamide were found to be more effective as compared to lignocaine. They were found to be non-irritant, and non-toxic even in high doses.engAcetamides --pharmacologyAnesthetics, LocalAnimalsGuinea PigsLethal Dose 50Lidocaine --pharmacologyProcaine --pharmacologyRabbitsComparative Study