van der Zanden, Adri G MRahim, ZeaurFedder, GuidoVos-van Adrichem, JanineSebens, Fré WHeilmann, Frank G Cvan Soolingen, Dick2009-05-272009-05-272007-07-22van der Zanden AG, Rahim Z, Fedder G, Vos-van Adrichem J, Sebens FW, Heilmann FG, van Soolingen D. Multiple Mycobacterium tuberculosis infections in an HIV-infected patient. The Southeast Asian Journal of Tropical Medicine and Public Health. 2007 Jul; 38(4): 704-5http://imsear.searo.who.int/handle/123456789/34538The Southeast Asian Journal of Tropical Medicine and Public Health.Mycobacterial colonies of two different morphologies were isolated from one sputum sample of a HIV-positive patient. One morphological type was resistant to streptomycin (STR) and susceptible to isoniazid (INH), while the other isolate with different colony morphology was resistant to both of these anti-TB drugs. A mycobacterial isolate of one pus from a lymph node sample was resistant to these two anti-TB drugs, while the other isolate from another pus sample was resistant to STR but susceptible INH. IS6110 RFLP based finger printing revealed that the HIV-positive patient was infected with different strains of Mycobacterium tuberculosis. A subculture of isolates on solid medium is useful to examine mixed infection.engAIDS-Related Opportunistic Infections --microbiologyAdultAntitubercular Agents --pharmacologyDNA FingerprintingDrug Resistance, Multiple, BacterialHumansLymph Nodes --microbiologyMaleMycobacterium tuberculosis --drug effectsNetherlandsSputum --microbiologyTuberculosis, Multidrug-Resistant --geneticsCase Reports