Singh, Vipul KumarPathak, Manoj KumarBihari, VipinJyotiPatel, Devendra KumarMathur, NeerajKesavachandran, C NSiddiqui, Mohd Kaleem Javed2013-05-062013-05-062011-01Singh Vipul Kumar, Pathak Manoj Kumar, Bihari Vipin, Jyoti, Patel Devendra Kumar, Mathur Neeraj, Kesavachandran C N, Siddiqui Mohd Kaleem Javed. Studies on oxidative stress induced nerve conduction deficits in cigarette smokers. Journal of Environmental Biology. 2011 Jan; 32(1): 39-42.http://imsear.searo.who.int/handle/123456789/146540An important role of oxidative stress for the development of vascular and neurological complications has encouraged us to undertake a study to assess the oxidative stress induced nerve conduction deficits among cigarette smokers. Eighteen regular male cigarette smokers and twenty nine male non - smokers were diagnosed for clinical neuro-physiological tests viz., motor and sensory nerve conduction velocity (MNCV and SNCV) and redox status. Significant depletion of reduced glutathione (GSH) level (p < 0.05) and significant increase in malondialdehyde (MDA) level (p < 0.01) was found in smokers compared to non - smokers. Motor and sensory nerve conduction velocity showed no significant difference among smokers compared to non - smokers. The present study shows that smoking can induce oxidative stress among smokers but could not exacerbate to nerve conduction deficits.enCigarette smokersOxidative stressNerve conduction deficitArticle