Aravinda, Voleti Sri SrujanaKrishna, K BalaRam, K ChaitanyaShekhar, M RaviMalleswarao, I Naga2023-07-142023-07-142022-06Aravinda Voleti Sri Srujana, Krishna K Bala, Ram K Chaitanya, Shekhar M Ravi, Malleswarao I Naga. Aggressive Central Giant Cell Granuloma in a Child: A Case Report and Review. Oral and Maxillofacial Pathology Journal. 2022 Jun; 13(1): 51-542322-03840976-1225http://imsear.searo.who.int/handle/123456789/218460Introduction: An aggressive variant of central giant cell granuloma in a paediatric patient is a localized benign osteolytic prolif- eration. The lesion consist of fibrous tissue with haemorrhage, hemosiderin deposits and presence of osteoclast-like giant cells with reactive bone formation. Clinically shown with rapid growth, resorption of roots, displacement of teeth and thinning or perforation of cortical bone, and marked recurrence. Case presentation: A 9-year-old boy reported with a 3 days history of asymptomatic soft tissue swelling in left mandibular pos- terior region which was diagnosed as central giant cell granuloma based on clinical, radiological and histopathological features. Management and Prognosis: Surgical resection was performed without any signs of recurrence on 9 months follow up. Conclusion: Prompt diagnosis and treatment of Central giant cell granuloma can significantly improve morbidity and long- term outcomes.Aggressive giant cell granulomaCentral giant cell granuloma.Journal ArticleIndiaDepartment of Paediatric and Preventive Dentistry, Anil Neeru- konda Institute of Dental Sciences, Visakhapatnam, Andhra Pradesh, India; Department of Oral and Maxillofacial Surgery, Anil Neerukonda Institute of Dental Sciences, Visakhapatnam, Andhra Pradesh, India.