Goyal, RohitChalamalasetty, Sreenivasa BabaMadan, KaushalPaul, Shashi BalaArora, RamanSafaya, RajniAcharya, Subrat K2007-11-242009-05-292007-11-242009-05-292007-11-24Goyal R, Chalamalasetty SB, Madan K, Paul SB, Arora R, Safaya R, Acharya SK. Acral and palmo-plantar hyperpigmentation in a patient with disseminated hepatocellular carcinoma. Indian Journal of Gastroenterology. 2007 Nov-Dec; 26(6): 292-3http://imsear.searo.who.int/handle/123456789/64428Capecitabine (5-fluorouracil prodrug) is being evaluated for the management of hepatocellular carcinoma, and is associated with a peculiar skin reaction called hand and foot syndrome (HFS). We describe one patient with HCC and drug-induced HFS.engAdministration, OralAntimetabolites, Antineoplastic --administration & dosageCarcinoma, Hepatocellular --drug therapyDeoxycytidine --administration & dosageDiagnosis, DifferentialFluorouracil --administration & dosageFoot Dermatoses --chemically inducedHand Dermatoses --chemically inducedHumansLiver Neoplasms --drug therapyMaleMiddle AgedAcral and palmo-plantar hyperpigmentation in a patient with disseminated hepatocellular carcinoma.Case Reports