Chandrashekaran, M KMarimuthu, GSubbaraj, RKumarasamy, PRamkumar, M SSripathi, K2015-07-282015-07-281991-09Chandrashekaran M K, Marimuthu G, Subbaraj R, Kumarasamy P, Ramkumar M S, Sripathi K. Direct correlation between the circadian sleep-wakefulness rhythm and time estimation in humans under social and temporal isolation. Journal of Biosciences. 1991 Sept; 16(3): 97-101.http://imsear.searo.who.int/handle/123456789/160758Several bodily functions in humans vary on a 24 h pattern and most of these variations persist with a circadian period of ca 25 h when subjects are studied under conditions of social and temporal isolation. We report in this paper that the estimates of short time intervals (TE) of 2 h are strongly coupled to the circadian rhythm in sleepwakefulness. There is a linear correlation between the number of hours humans stay awake (α) and their estimation of 2 h intervals. The coupling of TE to α appears to obtain only under conditions of physical well-being.enHuman circadian rhythmssleep-wakefulnesstemperaturefreerunsdissociationbiological oscillators and modelsArticle