Alkhowailed, Mohammad S.2020-04-092020-04-092019-11Alkhowailed Mohammad S.. A case of urticaria multiforme with unusual presentation. International Journal of Advances in Medicine. 2019 Nov; 6(6): 1946-19492349-39252349-3933http://imsear.searo.who.int/handle/123456789/194434Urticaria multiforme is a condition which manifests as acute, polycyclic, annular oedematous pink plaques with an ecchymosis hue that is associated with acral edema. The condition is often misdiagnosed as erythema multiforme, serum-sickness-like reactions, or urticarial vasculitis. Author present a case of acute annular urticaria in a 3-year-old girl who presented with unusual clinical manifestations of the condition. Through this case report, Author aim to emphasize the wide range of morphologic manifestations that can be seen in urticaria multiforme. This can assist pediatric physicians to differentiate urticaria multiforme from other clinical dermatologic conditions and prevent misdiagnosis. A detailed case history and physical examination, along with relevant diagnostic tests can enable prompt and effective management of the condition.Acute annular urticariaChildhood hypersensitivity reactionErythema multiformeHypersensitivitySerum sickness reactionUrticariaUrticaria multiformeJournal ArticleIndiaDepartment of Dermatology, College of Medicine, Qassim University Buraydah, Qassim, Saudi Arabia