Mutreja, DeeptiSivasami, KartikTewari, VanmaliniNandi, BhaskarNair, G LakhsmiPatil, Sunita D2016-01-182016-01-182015-10Mutreja Deepti, Sivasami Kartik, Tewari Vanmalini, Nandi Bhaskar, Nair G Lakhsmi, Patil Sunita D. A 36-year-old man with vomiting, pain abdomen, significant weight loss, hyponatremia, and hypoglycemia. Indian Journal of Pathology & Microbiology. 2015 Oct-Dec 58(4): 500-505.http://imsear.searo.who.int/handle/123456789/170508Diagnosis of Strongyloides stercoralis hyperinfection can be a challenge. The key to a timely diagnosis is to have a high index of suspicion. We present a rare case of a 36-year-old human immunodeficiency virus negative male patient, who was on multidrug therapy for lepromatous leprosy and was treated for type 2 lepra reactions with steroids in the past. The patient presented with vomiting and pain abdomen, persistent hyponatremia, and terminal hypoglycemia. He had features of malnutrition and had a rapid downhill course following admission. A diagnosis of S. stercoralis hyperinfection with sepsis and multiorgan failure, adrenal hemorrhage, and syndrome of inappropriate antidiuretic hormone secretion was established on a postmortem examination.enAdrenal crisishyponatremialeprosyStrongyloides stercoralis hyperinfectionArticle