Yadav, J SSeth, N2009-05-282009-05-282000-01-10Yadav JS, Seth N. Effect of diagnostic X-rays on somatic chromosomes of occupationally exposed workers. Indian Journal of Experimental Biology. 2000 Jan; 38(1): 46-50http://imsear.searo.who.int/handle/123456789/61931Investigations were carried out to estimate the level of radiation exposure effect of X-ray machines on 40 male personnel handling diagnostic X-ray machines and compared to 38 matched, unexposed, normal controls. The actual accumulated radiation doses were not disclosed. As compared to controls the exposed persons showed highly significantly increased levels (P < 0.01) of chromosome aberrations (0.68%-2.67%). Frequencies of sister chromatid exchanges (5.80-6.20) and the levels of aneuploidy (2.27-2.37) were also increased a little, but did not show statistically significant effect of exposure. Satellite associations (7.84-16.25) and mitotic index (5.14-6.07) showed a significant increase (P < 0.05) in exposed individuals. The statistically significant increase in the frequencies of chromosomal aberrations and satellite associations in X-ray personnel underscores the need of adopting measures to avoid or at least minimiZe overexposure to X-irradiation.engAdultAneuploidyCase-Control StudiesChromosome AberrationsChromosomes, Human --radiation effectsDose-Response Relationship, RadiationHumansMaleMitotic IndexMutagenicity TestsObserver VariationOccupational ExposureRadiation DosageRadiographySingle-Blind MethodSister Chromatid Exchange --radiation effectsTechnology, RadiologicJournal Article