Chotigeat, UraiwanJaratwashirakul, Santiwan2009-05-272009-05-272007-01-12Chotigeat U, Jaratwashirakul S. Inhaled iloprost for severe persistent pulmonary hypertension of the newborn. Journal of the Medical Association of Thailand. 2007 Jan; 90(1): 167-70http://imsear.searo.who.int/handle/123456789/44481Chotmaihet Thangphaet.The authors report one case of persistent pulmonary hypertension that had hypoxia although receiving treatment with high frequency oscillation, inotropic drugs, blood transfusion, and oral sildenafil for pulmonary vasodilatation. The patient developed hypotension after two doses of oral sildenafil and no response to high dose of inotropic drugs. So aerosolized iloprost was given via endotracheal tube and oxygen saturation improved within 10 minutes. Oxygen was weaned at 36 hours after treatment with this drug and no any side effect was found.engFemaleHigh-Frequency VentilationHumansHypotension --chemically inducedIloprost --administration & dosageInfant, NewbornIntubation, IntratrachealPersistent Fetal Circulation Syndrome --drug therapyPiperazines --adverse effectsPurines --adverse effectsSulfones --adverse effectsTreatment FailureVasodilator Agents --administration & dosageCase Reports